XU Zheng, YAN Xiaoqian, SHANG Xiuyang, et al. Clinical characteristics and long-term prognosis of type 2 cardiorenal syndrome patients with blood-stasis pattern[J]. Journal of Beijing University of traditional Chinese Medicine, 2016, 39(8): 690-695.
XU Zheng, YAN Xiaoqian, SHANG Xiuyang, et al. Clinical characteristics and long-term prognosis of type 2 cardiorenal syndrome patients with blood-stasis pattern[J]. Journal of Beijing University of traditional Chinese Medicine, 2016, 39(8): 690-695.DOI: 10.3969/j.issn.1006-2157.2016.08.015.
Clinical characteristics and long-term prognosis of type 2 cardiorenal syndrome patients with blood-stasis pattern
Objective To explore the clinical characteristics and the long-term prognosis of type 2 cardiorenal syndrome( CRS) patients with blood-stasis pattern. Methods 390 cases eligible were divided into CRS group and non-CRS group. After comparing TCM pattern elements between the two groups
we collected the related clinical data. Then all patients were followed-up for 1 810 days to get their final events( survive or dead). Using ROC curves plotted based on the relationship between renal function and long-term prognosis
patients were re-assigned into renal function level groups to try to find out the distribution of TCM pattern and the relationship of blood-stasis pattern with renal function or with modern medical indices. Results Blood-stasis pattern was positive correlated with renal function of chronic heart failure( CHF) patients( P = 0. 027)
but was negative correlated with qi deficiency pattern or yang deficiency pattern
maybe due to the progression of CRS. Conclusion The important effect of blood-stasis pattern on the occurrence and development was proved
and the blood-stasis pattern may indicate the deterioration
dysfunction of heart leading to dysfunction of kidney.