Distribution and characteristics of traditional Chinese medicine patterns in 165 patients with fibromyalgia syndrome

Yang LI; Yuruo SUN; Jingsi FU; Yanting LI; Juan JIAO

doi:10.3969/j.issn.1006-2157.2022.06.013

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Distribution and characteristics of traditional Chinese medicine patterns in 165 patients with fibromyalgia syndrome

Clinical Studies | 更新时间：2022-07-11

- Distribution and characteristics of traditional Chinese medicine patterns in 165 patients with fibromyalgia syndrome
- Journal of Beijing University of Traditional Chinese Medicine Vol. 45, Issue 6, Pages: 630-636(2022)
- 作者机构：
  
  中国中医科学院广安门医院风湿病科　北京　100053
- 作者简介：
  
  Prof. JIAO Juan, Ph.D., Chief Physician, Master’s Supervisor. Rheumatology Department, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, No. 5 Beixiange Street, Xicheng District, Beijing 100053. E-mail: jiao.juan@hotmail.com
- 基金信息：
  
  Special Research Project of Capital Clinical Innovation Application(Z181100001718153)
- DOI：10.3969/j.issn.1006-2157.2022.06.013
  CLC： R259
- Received：08 November 2021，
  
  Published：30 June 2022
- 稿件说明：
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Yang LI, Yuruo SUN, Jingsi FU, et al. Distribution and characteristics of traditional Chinese medicine patterns in 165 patients with fibromyalgia syndrome[J]. Journal of Beijing University of Traditional Chinese Medicine, 2022, 45(6): 630-636.
DOI：

Yang LI, Yuruo SUN, Jingsi FU, et al. Distribution and characteristics of traditional Chinese medicine patterns in 165 patients with fibromyalgia syndrome[J]. Journal of Beijing University of Traditional Chinese Medicine, 2022, 45(6): 630-636. DOI： 10.3969/j.issn.1006-2157.2022.06.013.

摘要

目的

调查纤维肌痛综合征(FMS)中医证候分布情况及不同证候患者的人口学特点和病情轻重程度。

方法

采用横断面调查研究方法，将中医证候分为寒湿痹阻证、肝郁气滞证、气滞血瘀证、肝胆湿热证、肝血亏虚证、肝肾不足证及复合证候(同时具有以上2种证候)，制定“纤维肌痛综合征中医证候调查问卷”。根据患者的应答进行数据分析，得到FMS中医证候分布情况，比较不同证候的人口学特点，并采用《视觉模拟评分法》《修订版纤维肌痛影响问卷》《匹兹堡睡眠质量指数》《多维疲劳量表》《贝克忧郁量表》《压力知觉量表》对患者病情进行评估。

结果

共165例患者参与调查。单一证候97例，分别为肝肾不足证27例(16.4%)、肝郁气滞证25例(15.2%)、气滞血瘀证17例(10.3%)、肝胆湿热证14例(8.5%)、寒湿痹阻证7例(4.2%)和肝血亏虚证7例(4.2%)，复合证候中肝郁气滞合肝血亏虚证最多，为34例(20.6%)，其他复合证候共34例(20.6%)。不同证候患者在性别、年龄、吸烟、教育程度、收入方面存在差异，肝血亏虚证患者病程较长，肝郁气滞证患者抑郁程度较高，寒湿痹阻证患者总体病情较轻。

结论

在FMS证候分布以实证及虚实夹杂证为主，少数为虚证。邪实主要见于气滞、血瘀、寒湿，正虚主要见于血虚、阴虚，阳虚者较少，病变脏腑主要在肝。FMS证候可能与人口学特点和病情程度有关。

Abstract

Objective

To investigate the distribution of traditional Chinese medicine (TCM) patterns of fibromyalgia syndrome (FMS) and compare the demographic characteristics and the severity of patients with different TCM patterns.

Methods

Using a cross-sectional survey

TCM patterns were divided into the cold dampness obstruction pattern

liver qi stagnation pattern

qi-blood stagnation pattern

liver-gall bladder damp-heat pattern

deficiency of liver and kidney pattern

deficiency of liver blood pattern

and combination patterns (two patterns involved at the same time). By administering the "FMS TCM Pattern Questionnaire"

we investigated the TCM pattern distribution of FMS patients and compared their demographic characteristics. Then

five internationally recognized evaluation scales of FMS were used to assess the severity of the condition

including the Visual Analogue Scale

Revised Fibromyalgia Impact Questionnaire

Pittsburgh Sleep Quality Index

Multidimensional Fatigue Inventory

Beck Depression Inventory

and Perceived Stress Scale.

Results

A total of 165 patients’ clinical information was collected; 97 FMS patients had a single TCM pattern

including 27 cases of the deficiency of liver and kidney pattern (16.4%)

25 cases of the liver qi stagnation pattern (15.2%)

17 cases of the qi-blood stagnation stasis pattern (10.3%)

14 cases of liver-gallbladder damp-heat pattern (8.5%)

7 cases of the cold dampness obstruction pattern (4.2%)

and 7 cases of the liver blood deficiency pattern (4.2%). Moreover

there were 34 cases of the combined liver qi stagnation pattern with liver blood deficiency pattern (20.6%) and 34 cases of other combined patterns (20.6%). Patients with different patterns had differences in gender

age

smoking

education level

and income. Patients with the liver blood deficiency pattern had a relatively long course of the disease. Patients with the liver qi stagnation pattern had a relatively high degree of depression. Finally

patients with the cold dampness obstruction pattern had a relatively mild overall condition.

Conclusion

In the distribution of FMS patterns

excess pattern and pattern of intermingled deficiency and excess are major

while deficiency pattern is only a small part. The excessive pathogens mainly include qi stagnation

blood stasis

and cold dampness

while the vital qi deficiency mainly includes blood deficiency and yin deficiency. The yang deficiency is relatively rare

and the pathological changes of viscera are mainly in the liver. Thus

TCM pattern typing may be related to demographic characteristics and the severity of disease.

关键词

Keywords

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