Discuss the etiology and pathogenesis of diabetic cardiomyopathy from the angle of blood stasis and poison

YANG Deshuang; HUANG Li; YAO Ruiqi; GUO Shuzhen

doi:10.3969/j.issn.1006-2157.2023.02.007

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Discuss the etiology and pathogenesis of diabetic cardiomyopathy from the angle of blood stasis and poison

Theoretical Studies | 更新时间：2023-03-07

- Discuss the etiology and pathogenesis of diabetic cardiomyopathy from the angle of blood stasis and poison
- Journal of Beijing University of Traditional Chinese Medicine Vol. 46, Issue 2, Pages: 181-185(2023)
- 作者机构：
  
  1.北京中医药大学研究生院　北京　100029
  2.中日友好医院中西医结合心内科
  3.北京中医药大学中医学院
- 作者简介：
  
  Prof. GUO Shuzhen, Ph.D., Doctoral Supervisor. Beijing University of Chinese Medicine, No. 11, Beisanhuan Donglu Road, Chaoyang District, Beijing 100029. E-mail: guoshz@ bucm.edu.cn
- 基金信息：
  
  National Natural Science Foundation of China(81922075)
- DOI：10.3969/j.issn.1006-2157.2023.02.007
  CLC： R246
- Received：06 July 2022，
  
  Published：28 February 2023
- 稿件说明：
移动端阅览
YANG Deshuang, HUANG Li, YAO Ruiqi, et al. Discuss the etiology and pathogenesis of diabetic cardiomyopathy from the angle of blood stasis and poison[J]. Journal of beijing university of traditional chinese medicine, 2023, 46(2): 181-185.
DOI：

YANG Deshuang, HUANG Li, YAO Ruiqi, et al. Discuss the etiology and pathogenesis of diabetic cardiomyopathy from the angle of blood stasis and poison[J]. Journal of beijing university of traditional chinese medicine, 2023, 46(2): 181-185. DOI： 10.3969/j.issn.1006-2157.2023.02.007.

摘要

糖尿病心肌病是糖尿病的并发症之一。中医学认为，其发病过程为胃纳太过，脾运不及，以致水谷壅滞于中焦，生成“糖毒”，“糖毒”入脉，毒随脉行，积于心中，血滞成瘀，久而化热为毒，瘀毒互结，久羁于心，毒损心之络脉，败伤心之正气，损伤功能，破坏形质。西医学认为，中医所谓的瘀毒是由体内异常代谢物质堆积所致。本团队基于中医学经典理论，结合现代临床及基础研究，从瘀毒角度出发，系统阐述糖尿病心肌病的病因病机，并提出根据瘀毒的程度，从整体与局部论治，合理运用化浊解毒、活血化瘀方药，同时根据瘀毒存在的时空节点进行分期论治，以期对糖尿病心肌病的基础研究和临床实践提供一定的借鉴。

Abstract

Diabetic cardiomyopathy (DCM) is one of the complications of diabetes. According to traditional Chinese medicine (TCM)

the pathogenesis of DCM is likely that

due to the overeating and the deficiency of spleen’s transport and transformation functions

water and grain are stuck in the middle jiao. The "sugar poison" is generated. The "sugar poison" enters the pulse

travels with the pulse

and accumulates in the heart. The blood stagnation becomes the blood stasis

the blood stasis produces heat and then turns into poison over time

and then blood stasis and poison intersect together. The blood stasis and the poison are confined in the heart for a long time

the poison damages the heart’s veins

defeats the vital qi of the heart

and then damages its function and body. According to Western medicine

blood stasis and poison in TCM are caused by accumulation of abnormal metabolic substances in the body. Based on the classical theory of TCM

combined with modern clinical and basic research

our team systematically expounds the etiology and pathogenesis of DCM from the perspective of blood stasis and poison. And our team proposes that according to the degree of blood stasis and poison

the prescriptions for removing turbidity and detoxification

promoting blood circulation and removing blood stasis could put forward from the whole and local perspectives. According to the spatio-temporal node of blood stasis and poison in the DCM and treat it by stages according to the nodes

so as to provide some experience for basic and clinical research.

关键词

Keywords

references

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