The similarities and differences in the pathogenesis of dampness attacking different parts of the body and the understanding of western medicine

CHEN Haoyin; LI Yifan; TANG Qinqi; WANG Lina; LUO Jie; LIAO Liting; GU Yueyu; LIU Xusheng; LU Chuanjian

doi:10.3969/j.issn.1006-2157.2023.07.011

您当前的位置：

首页 >

文章列表页 >

The similarities and differences in the pathogenesis of dampness attacking different parts of the body and the understanding of western medicine

Theoretical Studies | 更新时间：2023-08-07

- The similarities and differences in the pathogenesis of dampness attacking different parts of the body and the understanding of western medicine
- Journal of Beijing University of Traditional Chinese Medicine Vol. 46, Issue 7, Pages: 954-959(2023)
- 作者机构：
  
  1.广州中医药大学第二临床医学院　广州　510405
  2.广州中医药大学第二临床医学院　省部共建中医湿证国家重点实验室
- 作者简介：
  
  GU Yueyu, Ph. D., Associate Researcher. The Second Clinical College of Guangzhou University of Chinese Medicine, No.111, Dade Road, Yuexiu District, Guangzhou 510120. E-mail: guyy@gzucm.edu.cn
- 基金信息：
  
  China Postdoctoral Science Foundation(2021M690042;2022T150148);Guangzhou Basic and Applied Basic Research Foundation(202102020011);The Program of the State Key Laboratory of Dampness Syndrome of Chinese Medicine(BJ2022KY03)
- DOI：10.3969/j.issn.1006-2157.2023.07.011
  CLC： R228
- Received：10 October 2022，
  
  Published Online：16 March 2023，
  
  Published：30 July 2023
- 稿件说明：
移动端阅览
CHEN Haoyin, LI Yifan, TANG Qinqi, et al. The similarities and differences in the pathogenesis of dampness attacking different parts of the body and the understanding of western medicine[J]. Journal of beijing university of traditional chinese medicine, 2023, 46(7): 954-959.
DOI：

CHEN Haoyin, LI Yifan, TANG Qinqi, et al. The similarities and differences in the pathogenesis of dampness attacking different parts of the body and the understanding of western medicine[J]. Journal of beijing university of traditional chinese medicine, 2023, 46(7): 954-959. DOI： 10.3969/j.issn.1006-2157.2023.07.011.

摘要

湿邪是一种具有黏滞重浊、趋下特性的致病外邪，随着人们生活习惯的变化，湿证愈加多见。由于机体不同部位的特点、功能不一，湿邪侵袭时的病机也不一致，对其进行梳理，有利于临床诊疗。湿邪分内湿与外湿，本文拟以外湿由表入里的侵袭途径为线索，结合湿邪致病的特点，论述湿邪在机体各部位致病的临床表现，并比较其致病病机的异同。此外，本文还结合西医学的研究成果阐释湿邪的致病机理，更好地为中西医融合、提高临床诊疗效果和精准用药提供研究证据。

Abstract

Dampness is one of the important external pathogens in Chinese medicine

and with the changes in peoples living habits

dampness syndrome is becoming more and more common. Due to the different characteristics and functions of different parts of the body

the pathogenesis of dampness is not the same when it attacks

so it is helpful to examine it before clinical treatment. Dampness forms through inner unbalance or invades through external environment. This paper discusses the clinical manifestations of dampness in various parts of the body and highlights the similarities and differences in the pathogenic mechanisms of dampness

taking into account the pathogenic characteristics of dampness as a clue for the external dampness invasion pathway from the surface to the inside. In addition

this paper also explains the disease mechanism of dampness syndrome in the context of western medical research

so as to provide research evidence for the integration of Chinese and western medicine and to improve medical treatment in clinical practice.

关键词

Keywords

references

王良，黄秀深，杨成，等．湿阻中焦证动物模型胃肠水通道蛋白1的病理特征分布研究 [J]. 时珍国医国药， 2011 ， 22 ( 9 ): 2279 - 2281 .

王文竹，杨忠华．湿邪层次病机证治探讨 [J]. 中国中医药现代远程教育， 2021 ， 19 ( 5 ): 131 - 133 .

路志正，路洁．北方亦多湿续论 [J]. 中华中医药杂志， 2006 ， 21 ( 9 ): 515 - 518 .

王琦，朱燕波．中国一般人群中医体质流行病学调查：基于全国9省市21 948例流行病学调查数据 [J]. 中华中医药杂志， 2009 ， 24 ( 1 ): 7 - 12 .

JAIN A , AGGARWAL A , ADAMS J , et al . Delay in seeking medical help in patients with rheumatoid arthritis in India: A qualitative study [J]. Int J Rheum Dis , 2020 , 23 ( 12 ): 1707 - 1718 .

肖森茂．再论“湿邪致病”特性 [J]. 陕西中医， 2000 ， 21 ( 11 ): 508 - 509 .

叶惠珍，黄水霞，张丽霞．中药健脾渗湿汤对脾虚湿盛泄泻患者肠道微生态及舌象变化的影响 [J]. 中国民间疗法， 2020 ， 28 ( 9 ): 55 - 58 .

李广瑞，杨嗣福，欧阳恒．湿疹治疗的难点及中医对策 [J]. 中国中西医结合皮肤性病学杂志， 2010 ， 9 ( 4 ): 253 - 255 .

吴先林，陈孝银．从中西医免疫观探讨“湿性黏滞”的本质 [J]. 辽宁中医杂志， 2010 ， 37 ( 5 ): 832 - 833 .

呼永河，田卫卫，钟梁． “久湿入络”理论初探 [J]. 西南国防医药， 2011 ， 21 ( 1 ): 75 - 76 .

呼永河，钟梁，李静，等．湿与脏腑相关性之刍议 [J]. 西南国防医药， 2013 ， 23 ( 6 ): 680 - 681 .

刘宗莲，路洁，王秋风，等．国医大师路志正从湿辨治冠心病学术思想初探 [J]. 中华中医药杂志， 2010 ， 25 ( 3 ): 379 - 381 .

施学丽，郭超峰，范丽丽，等．肝失疏泄与五脏生湿关系的机理辨析 [J]. 广西中医药， 2019 ， 42 ( 1 ): 33 - 35 .

林颖．陈达灿“中土为枢，从脾论治”疑难皮肤病学术思想 [J]. 中华中医药杂志， 2022 ， 37 ( 1 ): 239 - 242 .

张晓红．湿疹病因病机及其临床研究 [J]. 中国临床医生， 2011 ， 39 ( 2 ): 14 - 16 .

朱聪聪，潘会君，朱全刚． Th2相关炎症因子在湿疹发病中的作用机制 [J]. 药学实践杂志， 2019 ， 37 ( 1 ): 9 - 13 .

张建中．银屑病的流行病学与危险因素 [J]. 实用医院临床杂志， 2013 ， 10 ( 1 ): 4 - 6 .

闫雪柔，纪越，尚懿纯． “地之湿气，感则害皮肉筋脉”之探讨 [J]. 中国中医基础医学杂志， 2017 ， 23 ( 6 ): 758 - 759 .

李柱一，张巍．重症肌无力发病机制和治疗的回顾与展望 [J]. 中国现代神经疾病杂志， 2012 ， 12 ( 2 ): 113 - 116 .

刘哲君，林新锋，赵馥，等． ICU获得性肌无力的发病与中医“痿证”相关性的探讨 [J]. 中医药导报， 2018 ， 24 ( 11 ): 33 - 35 .

武晏屹，白明，田硕，等．基于中西医临床病症特点的膝骨关节炎动物模型分析 [J]. 中国中药杂志， 2020 ， 45 ( 11 ): 2481 - 2485 .

袁普卫，何辉，康武林，等．膝骨性关节炎患者滑膜水通道蛋白－1表达与血管生成的相关性研究 [J]. 中国矫形外科杂志， 2015 ， 23 ( 11 ): 1025 - 1032 .

张声生，李乾构，魏玮，等．肠易激综合征中医诊疗共识意见 [J]. 中华中医药杂志， 2010 ， 25 ( 7 ): 1062 - 1065 .

FORD AC , SPERBER AD , CORSETTI M , et al . Irritable bowel syndrome [J]. Lancet , 2020 , 396 ( 10263 ): 1675 - 1688 .

周正华．肠道微环境与溃疡性结肠炎 [J]. 世界华人消化杂志， 2016 ， 24 ( 11 ): 1695 - 1700 .

孙荣．宣肺乃治湿之要法 [J]. 吉林中医药， 2011 ， 31 ( 3 ): 191 - 192 .

张迪，张冬梅，陆瑞敏，等．基于“肺主行水”理论探究小青龙汤调节肺水转运蛋白的作用机制 [J]. 中国实验方剂学杂志， 2022 ， 28 ( 8 ): 1 - 11 .

MILANZI EB , KOPPELMAN GH , SMIT HA , et al . Timing of secondhand smoke, pet, dampness or mould exposure and lung function in adolescence [J]. Thorax , 2020 ， 75 ( 2 ): 153 - 163 .

DUAN JF , XIE J , DENG T , et al . Exposure to both formaldehyde and high relative humidity exacerbates allergic asthma by activating the TRPV4－p38 MAPK pathway in Balb/c mice [J/OL]. Environ Pollut , 2020 ， 256 : 113375 [ 2022-09-01 ]. https://www.sciencedirect.com/science/article/abs/pii/S026974911933814X?via%3Dihub .

王梓楠，李磊．高仲山从肝脾肾论治带下病经验 [J]. 吉林中医药， 2020 ， 40 ( 5 ): 607 - 609 .

WANG YL , FENG Y , LI MM , et al . Traditional Chinese Medicine in the Treatment of Chronic Kidney Diseases: Theories, Applications, and Mechanisms [J/OL]. Front Pharmacol , 2022 , 13 : 917975 [ 2022-09-01 ]. https://www.frontiersin.org/articles/10.3389/fphar.2022.917975/full .

陈继红，高坤．孙伟以肾虚湿瘀立论揭示慢性肾脏病发病机制 [J]. 辽宁中医杂志， 2007 ， 34 ( 4 ): 420 .

沈金峰，胡芳，黄伟，等．肾纤维化中医病机与Wnt/β－catenin信号通路的关系 [J]. 中国中医基础医学杂志， 2018 ， 24 ( 11 ): 1548 - 1549 .

刘西洋．基于“肠－肝”轴探讨非酒精性脂肪性肝病湿热证的发病机制 [D]. 成都：成都中医药大学， 2020 .

刘彤，刘悦，陈莹，等．从脾主运化水湿理论探讨冠心病的发病机制 [J]. 中医杂志， 2017 ， 58 ( 6 ): 455 - 459 .

LAN TH , ZENG QH , JIANG W , et al . Metabolism disorder promotes isoproterenol-induced myocardial injury in mice with high temperature and high humidity and high-fat diet [J/OL]. BMC Cardiovasc Disord , 2022 , 22 ( 1 ): 133 [ 2022-09-01 ]. https://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-022-02583-z .

ABRIGNANI MG , LOMBARDO A , BRASCHI A , et al . Climatic influences on cardiovascular diseases [J]. World J Cardiol , 2022 , 14 ( 3 ): 152 - 169 .

黄韶华，沈义庆．高温高湿环境对人情绪的影响 [J]. 中国医药科学， 2016 ， 6 ( 4 ): 221 - 222 .

张昕贤，吴锋，林日阳，等．从肺脾肾不同组织水通道蛋白变化研究中医“水液代谢理论”的实验基础 [J]. 南方医科大学学报， 2012 ， 32 ( 10 ): 1507 - 1510 .

Views

450

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Pathogenesis and treatment strategies of cancer-related cognitive impairment from the perspective of " toxin damaging brain collaterals"

Analysis of the treatment method of chronic cough in children from the perspective of "xuanfu loss of function"

Between "analogy" and "definition" : the denotation of TCM terminology of etiology and pathogenesis in traditional Chinese medicine

Discussion on the etiology, pathogenesis and treatment of symptomatic intracranial atherosclerotic stenosis from "collateral deficiency and toxin damage"

Discussion of "unblocking and supplementing extraordinary vessels and treating them separately" in tumor pattern differentiation and treatment based on the theory of innateness from Huangdi Neijing

Related Author

ZHANG Mei

WU Yue

WANG Mingqi

WANG Miaomiao

CHEN Jie

SU Li

YU Junhao

LIU Miaomiao

Related Institution

Graduate School of Anhui University of Traditional Chinese Medicine

Graduate School of Beijing University of Chinese Medicine

Oncology Center of Integrated Traditional Chinese and Western Medicine, Anhui Medical University

Department of Oncology of Integrated Traditional Chinese and Western Medicine, The First Affiliated Hospital of Anhui Medical University

Dongzhimen Hospital, Beijing University of Chinese Medicine

AI问答

Postal code：100029
Tel：(010)53911857 Email：jbutcm@bucm.edu.cn
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰