Exploring traditional Chinese medicine-based diagnosis and treatment of breast cancer based on molecular typing
Hematology and Oncology|更新时间:2023-08-07
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Exploring traditional Chinese medicine-based diagnosis and treatment of breast cancer based on molecular typing
Journal of Beijing University of Traditional Chinese MedicineVol. 46, Issue 7, Pages: 1025-1031(2023)
作者机构:
1.济宁市第一人民医院 济宁 272002
2.山东大学齐鲁医学院
3.济宁医学院临床医学院
4.浙江中医药大学附属杭州市中医院
5.北京中医药大学东直门医院
作者简介:
JIANG Shulong, Ph.D., Chief Physician, Doctoral Supervisor. Jining First People's Hospital, No.6, Health Road, Rencheng District, Jining 272002. E-mail: jnsljiang@163.com
基金信息:
National Natural Science Foundation of China(82074360);Shandong Taishan Scholars Young Experts Project(tsqn201909200);Construction Project of National Famous Chinese Medicine Expert Inheritance Studio of State Administration of Traditional Chinese Medicine(2022YXNS170);Construction Project of National Famous Old Chinese Medicine Experts Inheritance Studio of State Administration of Traditional Chinese Medicine(国中医药人教函〔2022〕75号)
ZHANG Yiming, TIAN Xinchen, WANG Yufei, et al. Exploring traditional Chinese medicine-based diagnosis and treatment of breast cancer based on molecular typing[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023, 46(7): 1025-1031.
DOI:
ZHANG Yiming, TIAN Xinchen, WANG Yufei, et al. Exploring traditional Chinese medicine-based diagnosis and treatment of breast cancer based on molecular typing[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023, 46(7): 1025-1031.DOI: 10.3969/j.issn.1006-2157.2023.07.022.
Exploring traditional Chinese medicine-based diagnosis and treatment of breast cancer based on molecular typing
breast cancer is classified into four molecular types: Luminal A
Luminal B
human epidermal growth factor receptor 2 (HER-2)-positive
and triple negative. By summarizing and analyzing the studies published in the past decade
including the correlation between molecular types of breast cancer and traditional Chinese medicine(TCM) patterns
as well as the connection between the TCM constitution and clinical characteristics of different molecular types of breast cancer
this study reveals that there are differences in TCM patterns between different types of breast cancer. Notably
the pattern of liver depression and qi stagnation and the pattern of thoroughfare-controlling vessel disharmony are common contributors to the development of Luminal A and B breast cancer. In patients with HER-2-positive breast cancer
the main pathogenic mechanism is that wind
an exterior pathogen in Chinese medicine
complicated with phlegm and static blood
flows through the channels. In patients with triple-negative breast cancer
toxin
phlegm
and static blood are cemented in the channels. Therefore
in TCM-based diagnosis and treatment of breast cancer
it is necessary to make targeted changes according to the pathogenesis characteristics of different molecular types based on the core treatment principle of soothing the liver and invigorating the spleen
paying attention to the balance of qi
blood
and yin and yang and achieving accurate TCM differentiation and treatment with the integration of disease differentiation
molecular typing
and pattern differentiation.
关键词
Keywords
references
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Analysis of traditional Chinese medicine syndromes and constitution characteristics in patients with angina pectoris of coronary heart disease across different metabolic-weight types
Full-cycle management,syndrome differentiation,and treatment of breast cancer from the perspective of "six differentiation" thinking in traditional Chinese medicine clinical practice∗
Correlation between traditional Chinese medicine Constitution types,fluid intelligence,and functional connectivity in brain regions among 96 college students
Dynamic mutual damage between breast cancer and mixed anxiety and depressive disorder:a traditional Chinese medicine analysis of "earth stagnation and wood depression" theory
Pathogenesis and treatment of breast cancer from the perspective of " blood cold accumulation at the uterine ostium"
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