Using the principle of critical slowing down to discuss the pre-disease status of glucose homeostasis imbalance

SHI Kangle; LIU Xiaoyu; HU Ying; WANG Xiaocong; YANG Fangyan; LEI Cong; WANG Shiyao; YU Xinping; WANG Juan; YU Yuefan; MENG Qinggang

doi:10.3969/j.issn.1006-2157.2023.08.001

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Using the principle of critical slowing down to discuss the pre-disease status of glucose homeostasis imbalance

Special Theme: Preventive Treatment of Disease | 更新时间：2023-09-08

- Using the principle of critical slowing down to discuss the pre-disease status of glucose homeostasis imbalance
- Journal of Beijing University of Traditional Chinese Medicine Vol. 46, Issue 8, Pages: 1037-1047(2023)
- 作者机构：
  
  1.中国科学院大学　北京　100049
  2.北京中医药大学
  3.黑龙江中医药大学
- 作者简介：
  
  Prof. MENG Qinggang, Ph. D., Chief Physician, Doctoral Supervisor. Beijing University of Chinese Medicine, No. 11, Beisanhuan Donglu Road, Chaoyang District, Beijing 100029. E-mail: mqgangzy@126.com
- 基金信息：
  
  National Natural Science Foundation of China(82174530)
- DOI：10.3969/j.issn.1006-2157.2023.08.001
  CLC： R211
- Received：22 February 2023，
  
  Online First：02 June 2023，
  
  Published：30 August 2023
- 稿件说明：
移动端阅览
SHI Kangle, LIU Xiaoyu, HU Ying, et al. Using the principle of critical slowing down to discuss the pre-disease status of glucose homeostasis imbalance[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023, 46(8): 1037-1047.
DOI：

SHI Kangle, LIU Xiaoyu, HU Ying, et al. Using the principle of critical slowing down to discuss the pre-disease status of glucose homeostasis imbalance[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023, 46(8): 1037-1047. DOI： 10.3969/j.issn.1006-2157.2023.08.001.

摘要

中医学使用阴平阳秘的相对平衡状态界定人的健康，即健康是人体这个开放复杂巨系统整体动态平衡的稳态。稳态失衡则进入狭义的未病状态，邪正相争，存在向愈与向疾的两种演化趋势，一旦扰动过强或干预不力，则系统持续失稳，突变形成疾病稳态。治未病理论作为一种重要的实践原则，贯穿中医预防、诊断、治疗、康复的临床过程始终，对于多种疾病未病人群的筛查与早期干预具有重要的指导意义。本文围绕生理意义巨大、病理影响广泛的血糖失稳态，详述其防治意义、筛查现状与干预方式，系统分析其作为多种重大疾病未病状态的临界慢化原理，阐释中医治未病方法论所蕴含的基于系统整体性与开放性的藏－象映射模型思维、基于系统动态发展的临界慢化模型思维，探讨基于中医四诊合参的未病状态识别与干预路径，以期为复杂性科学视域下的中医诊疗模式研究提供参考。

Abstract

Traditional Chinese medicine uses the relative balance of yin and yang to define human health

that is

the steady-state of the overall dynamic balance of the entire open complex system. Steady-state disequilibrium means that the human body enters a narrow pre-disease state

where healthy qi and pathogenic factors compete

and there are two evolutionary trends

namely

healing and disease. Once the disturbance is too strong or the intervention is not effective

the system will continue to lose stability

and the mutation will form a stable disease state. As an important practical principle

the theory of "prevention of disease" runs through the clinical process of prevention

diagnosis

treatment

and rehabilitation of traditional Chinese medicine

and has important guiding significance for the screening and early intervention of the pre-disease population. This article focuses on blood glucose instability

which has great physiological significance and extensive pathological effects

elaborates its prevention and treatment significance

screening status

and intervention method

systematically analyzes its critical slowing principle as a pre-disease state of many major diseases

and explains the "viscera-state" mapping model based on system integrity and openness and the critical slowing model based on the dynamic development of the system contained in the disease prevention methodology of traditional Chinese medicine. This paper discusses the identification and intervention path of pre-disease status based on the "fourfold diagnosis combined with participation" of traditional Chinese medicine

with the aim to provide a reference for the diagnostic and treatment research of traditional Chinese medicine in view of complexity science.

关键词

Keywords

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School of Traditional Chinese Medicine, Beijing University of Chinese Medicine

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