The pathogenesis of pan-vascular disease explored from the perspective of "yin fire causes collateral disease"

SHEN Xinhui; YANG Yufeng; YU Chenghao; SHI Yan

doi:10.3969/j.issn.1006-2157.2023.09.015

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The pathogenesis of pan-vascular disease explored from the perspective of "yin fire causes collateral disease"

Clinical Studies | 更新时间：2023-10-09

- The pathogenesis of pan-vascular disease explored from the perspective of "yin fire causes collateral disease"
- Journal of Beijing University of Traditional Chinese Medicine Vol. 46, Issue 9, Pages: 1296-1300(2023)
- 作者机构：
  
  辽宁中医药大学　沈阳　110847
- 作者简介：
  
  Prof .SHI Yan, Ph.D.. Liaoning University of Traditional Chinese Medicine, Huanggu District, No. 79, Chongshan East Road, Shenyang 110847. E-mail: 446196375@163.com
- 基金信息：
  
  National Leading Talent Support Program for Traditional Chinese Medicine-Qihuang Scholar;Key Laboratory of Diabetes of Integrating Traditional Chinese Medicine with Diseases and Syndromes in Liaoning Province(2019JH6/10100009)
- DOI：10.3969/j.issn.1006-2157.2023.09.015
  CLC： R259.43
- Received：22 February 2023，
  
  Online First：20 July 2023，
  
  Published：30 September 2023
- 稿件说明：
移动端阅览
SHEN Xinhui, YANG Yufeng, YU Chenghao, et al. The pathogenesis of pan-vascular disease explored from the perspective of "yin fire causes collateral disease"[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023, 46(9): 1296-1300.
DOI：

SHEN Xinhui, YANG Yufeng, YU Chenghao, et al. The pathogenesis of pan-vascular disease explored from the perspective of "yin fire causes collateral disease"[J]. Journal of Beijing University of Traditional Chinese Medicine, 2023, 46(9): 1296-1300. DOI： 10.3969/j.issn.1006-2157.2023.09.015.

摘要

泛血管医学是近年来的新兴学科，泛血管疾病是以动脉粥样硬化为共同病理特征的系统性血管疾病。目前，泛血管疾病研究存在病机认识不全面、作用机制阐述不清晰等问题。中医药在泛血管疾病的防治中具有一定优势。阴火理论是李东垣的重要思想，认为机体因脾胃受损，元气匮乏，气火失衡，阴火内生。络病理论是中医理论体系的重要组成部分，慢性疾病随着病程演变最终会发展成络病。阴火是络病的关键病理环节，络病是阴火发生发展的必然结果。本文在阴火理论与络病理论指导下，以创新理论推动中医药发展为出发点，从阴火病络角度提出泛血管疾病“气火失衡、浊瘀毒络”的病机，并对其进行理论探析。

Abstract

Pan-vascular medicine is a new idea and concept proposed to crack the discipline division and focus on target organs that has emerged as a medical discipline in recent years. Pan-vascular disease is a systemic vascular disease with atherosclerosis as a common pathological feature. At present

researches on pan-vascular diseases have problems such as an incomplete understanding of pathogenesis and unclear elaboration of the mechanism of action. However

traditional Chinese medicine has certain advantages in the prevention and treatment of pan-vascular diseases. Yin fire theory is an important idea of LI Dongyuan. When the spleen and stomach are damaged

there is a lack of original qi and an imbalance of qi and fire

leading to internal yin fire is endogenous. The theory of collateral diseases is an important component of the theoretical system of traditional Chinese medicine

and chronic diseases will eventually develop into collateral diseases as the course of the disease evolves. Yin fire is a key pathological link in collateral diseases

and collateral diseases are an inevitable result of the occurrence and development of yin fire. Under the guidance of yin fire theory and collateral disease theory

this paper adopts an innovative theory to promote the development of traditional Chinese medicine as the starting point

then advances the new pathogenesis of pan-vascular disease

"qi and fire imbalance resulting in turbidity

and poisonous collateral" from the perspective of "yin fire causes collateral disease" and theoretically explores it.

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Keywords

references

ZHOU MG , WANG HD , ZENG XY , et al . Mortality, morbidity, and risk factors in China and its provinces, 1990－2017: a systematic analysis for the Global Burden of Disease Study 2017 [J]. Lancet , 2019 ， 394 ： 1145 － 1158 .

LANZER P , TOPOL EJ . Panvascular medicine: integrated clinical management [M]. Berlin ： Springer ， 2002 ： 1939 .

杨靖，王克强，霍勇，等．泛血管疾病综合防治科学声明 [J]. 中国循环杂志， 2019 ， 34 ( 11 )： 1041 － 1046 .

符伟国，杨靖，葛均波．如何认识泛血管医学 [J]. 中华医学信息导报， 2020 ， 35 ( 17 )： 20 － 20 .

葛均波．深化系统生物学理念推进泛血管医学学科发展 [J]. 中华心血管病杂志， 2016 ， 44 ( 5 )： 373 － 374 .

杨靖，张英梅，葛均波．泛血管疾病的筛查和早期发现 [J]. 上海医学， 2022 ， 45 ( 5 )： 293 － 297 .

曾倩倩，蔡佳蔚，岳仁宋．糖尿病合并骨质疏松症与阴火因机证治的相关性探讨 [J]. 四川中医， 2021 ， 39 ( 4 )： 35 － 37 .

程革．《金匮要略》络病理论探讨 [J]. 中医药学刊， 2004 ， 22 ( 12 )： 2308 － 2309 .

张亚萍，唐振宇，李永亮 . 论叶天士对张仲景通络法的继承与发挥 [J]. 上海中医药杂志， 2017 ， 51 ( 9 )： 37 － 39 .

王永炎，常富业，杨宝琴．病络与络病对比研究 [J]. 北京中医药大学学报， 2005 ， 28， ( 3 )： 1 － 6 .

吴以岭．脉络学说构建及其指导血管病变防治研究 [J]. 中国中西医结合杂志， 2017 ， 37 ( 2 )： 147 － 148 .

LIBBY P , BURING JE , BADIMON L , et al . Atherosclerosis [J]. Nat Rev Dis Primers ， 2019 ， 5 ( 1 )： 56 [ 2023－01－20 ]. https：//www.nature.com/articles/s41572－019－0106－z https：//www.nature.com/articles/s41572－019－0106－z .

VAN WOUDENBERGH GJ , THEOFYLAKTOPOULOU D , KUIJSTEN A , et al . Adapted dietary inflammatory index and its association with a summary score for low-grade inflammation and markers of glucose metabolism: the Cohort study on Diabetes and Atherosclerosis Maastricht(CODAM) and the Hoorn study [J]. Am J Clin Nutr , 2013 , 98 ( 6 )： 1533 － 1542 .

王丽英，张红敏，谢春光，等．中医释义动脉粥样硬化及2型糖尿病低度炎症的发生条件 [J]. 时珍国医国药， 2005 ， 16 ( 7 )： 662 － 663 .

冯桂贞，曾谷兰，吕崇山．低度炎症病理状态的中医病机分析 [J]. 中华中医药学刊， 2013 ， 31 ( 8 )： 1768 － 1770 .

张红敏，谢春光，陈世伟．低度炎症的中医病因探讨 [J]. 新中医， 2005 ， 37 ( 1 )： 14 － 16 .

叶招娣，孙倩倩，刘中勇．基于阴火理论探讨冠心病的治疗思路 [J]. 中医药通报， 2022 ， 21 ( 1 )： 22 － 25 .

陈学习，张英杰，李美霞，等．脾虚证与免疫系统关系研究概况与思考 [J]. 中国当代医药， 2010 ， 17 ( 34 )： 6 － 8 .

孙璐，黄水清，马文静，等．当归补血汤对RAW264.7细胞的TNF－α、ICAM－1表达的作用 [J]. 北京中医药大学学报， 2010 ， 33 ( 1 )： 33 － 35 .

彭许金．补中益气汤治疗脑动脉粥样硬化的效果 [J]. 中国当代医药， 2019 ， 26 ( 9 )： 133 － 135 .

黄琦，万强，刘言薇，等．基于“阴火”理论试析动脉粥样硬化炎症机制的中医内涵 [J]. 世界科学技术—中医药现代化， 2020 ， 22 ( 8 )： 2942 － 2947 .

吴以岭． “脉络—血管系统病”新概念及其治疗探讨 [J]. 疑难病杂志， 2005 ， 4 ( 5 )： 285 － 287 .

常成成，魏聪，吴以岭．脉络学说“孙络－微血管”概念及其临床指导意义 [J]. 中医杂志， 2016 ， 57 ( 1 )： 7 － 11 .

吴以岭 . 络病学概要 [ J ] . 疑难病杂志， 2004 ， 3 ( 1 )： 37 － 39 .

尤良震，赵晨，张晓雨，等 . 病络理论下泛血管疾病中西医结合防治理论基础及实施思路 [J]. 中国中西医结合杂志， 2022 ， 42 ( 11 )： 1392 － 1395 .

冯玮，陈志刚．络病学说的历程及现状 [J]. 北京中医药， 2009 ， 28 ( 8 )： 603 － 606 .

张浩洋，庞立健，刘创，等．基于慢性复杂性疾病“络虚邪瘀”理论探讨器官纤维化共性病机及治疗 [J]. 中医杂志， 2017 ， 58 ( 18 )： 1562 － 1565 .

孙文东．从阴火论治糖尿病下肢血管病变临床研究 [J]. 中医学报， 2017 ， 32 ( 8 )： 1420 － 1422 .

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