Exploring the relationship between intestinal flora and postmenopausal osteoporosis based on the theory of "earth restricting water"

LI Tongtong; MA Weiwei; XIONG Yong; ZHOU Guangwen; WEN Feng

doi:10.3969/j.issn.1006-2157.2023.10.007

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Exploring the relationship between intestinal flora and postmenopausal osteoporosis based on the theory of "earth restricting water"

Theoretical Studies | 更新时间：2023-11-06

- Exploring the relationship between intestinal flora and postmenopausal osteoporosis based on the theory of "earth restricting water"
- Journal of Beijing University of Traditional Chinese Medicine Vol. 46, Issue 10, Pages: 1367-1373(2023)
- 作者机构：
  
  1.湖北中医药大学针灸骨伤学院　武汉　430061
  2.湖北中医药大学附属医院
- 作者简介：
  
  A/Prof. XIONG Yong, Ph.D., Associate Physician, Master’s Supervisor. School of Acupuncture-Moxibustion and Orthopedics, Hubei University of Chinese Medicine, No.188, Tanhualin, Wuchang District, Wuhan 430061. E-mail: xiongyong1978@163.com
- 基金信息：
  
  National Natural Science Foundation of China(81904267);Scientific Research Plan Guiding Project of Hubei Provincial Department of Education in 2022(B2022107);Traditional Chinese Medicine Scientific Research Project of Hubei Provincial Administration of Traditional Chinese Medicine in 2023-2024(ZY2023Q005)
- DOI：10.3969/j.issn.1006-2157.2023.10.007
  CLC： R271.9
- Received：16 April 2023，
  
  Published Online：14 August 2023，
  
  Published：30 October 2023
- 稿件说明：
移动端阅览
LI Tongtong, MA Weiwei, XIONG Yong, et al. Exploring the relationship between intestinal flora and postmenopausal osteoporosis based on the theory of "earth restricting water"[J]. Journal of beijing university of traditional chinese medicine, 2023, 46(10): 1367-1373.
DOI：

LI Tongtong, MA Weiwei, XIONG Yong, et al. Exploring the relationship between intestinal flora and postmenopausal osteoporosis based on the theory of "earth restricting water"[J]. Journal of beijing university of traditional chinese medicine, 2023, 46(10): 1367-1373. DOI： 10.3969/j.issn.1006-2157.2023.10.007.

摘要

绝经后骨质疏松症是一种女性在绝经期后发生的骨代谢疾病，中医学将其归属为“骨痿”“骨蚀”等范畴。近年来，绝经后骨质疏松症与肠道菌群关联的研究逐渐深入。本文以中医学五行生克思想为基础，引用李东垣《脾胃论》中的“脾病则下流乘肾，土克水，则骨乏无力，是为骨蚀”观点，提出“土克水”致痿的理论。基于该理论基础，本文探讨脾虚、肾虚、痰浊三者在绝经后骨质疏松症病理过程中所起的作用，并阐释肠道菌群在其中的媒介角色。由此提出“脾土－肠道菌群－肾水－绝经后骨质疏松症”完整治疗链，为临床治疗绝经后骨质疏松症提供新的思路。

Abstract

Postmenopausal osteoporosis is a bone metabolism disease that occurs in women after menopause and is categorized in Chinese medicine as "bone flaccidity" and "bone erosion". In recent years

postmenopausal osteoporosis has been closely associated with studies on intestinal flora. Based on the generating-restricting relationship between the five elements in Chinese medicine and LI Dongyuan’s view that "when the spleen is sick

water-dampness flows downward to the kidney

and when the earth restricts water

the bones become weak and feeble

resulting in bone erosion" in

Piwei Lun

this article puts forward the theory that "earth restricting water" causes flaccidity. Building upon this theoretical foundation

we explore the roles of spleen deficiency

kidney deficiency

and phlegm turbidity in the pathologic process of postmenopausal osteoporosis

while highlighting the role of intestinal flora as a mediator in this process. We propose a comprehensive therapeutic approach involving the interplay of "spleen earth-intestinal flora-kidney water-postmenopausal osteoporosis"

which offers a new perspective for the clinical treatment of postmenopausal osteoporosis.

关键词

Keywords

references

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