

浏览全部资源
扫码关注微信
中国中医科学院广安门医院 北京 100053
Prof.HAN Fei, Chief Physician, Doctoral Supervisor. Guang ’anmen Hospital, China Academy of Chinese Medical Sciences.No.5, Beixiange, Xicheng District, Beijing 100053. E-mail: hanfei@gamyy.cn
Received:22 April 2023,
Published Online:24 October 2023,
Published:30 November 2023
移动端阅览
CUI Yuehua, HAN Fei. Discussion on treatment of childhood autism based on "kidney timidity and aphasia"[J]. Journal of beijing university of traditional chinese medicine, 2023, 46(11): 1587-1591.
CUI Yuehua, HAN Fei. Discussion on treatment of childhood autism based on "kidney timidity and aphasia"[J]. Journal of beijing university of traditional chinese medicine, 2023, 46(11): 1587-1591. DOI: 10.3969/j.issn.1006-2157.2023.11.014.
儿童孤独症是儿童常见的一种精神及行为障碍疾病。钱乙《小儿药证直诀》提出“虽有声而不能言,又能咽药,此非失音,为肾怯”。本文基于钱乙“肾怯失音”理论,试将其引入儿童孤独症的证治探究,结合儿童生理病理特点及儿童孤独症相关症状,基于中医学异病同治、整体观念等思维,提出儿童孤独症病机为肾阴不足、肾精亏虚,病位在脑,与心、肝、脾、肾有关。钱乙在肾气丸的基础上创立六味地黄丸,用以治疗小儿肾怯相关疾病。本文根据儿童孤独症病机并结合钱乙六味地黄丸分析探讨儿童孤独症的治则治法,从中医学角度更深入地了解儿童孤独症,期望寻找切实有效的治疗方法,开拓中医药治疗儿童孤独症的思路。
Childhood autism is a common mental and behavioral disorder in children. In the
Key to Therapeutics of Children
’
s Diseases
Qian Yi suggested that "although children have a voice and can swallow medicine
but can not speak
this is not aphasia
for the kidney timidity". Based on the theory of "kidney timidity and aphasia"
combined with the physiological and pathological characteristics of childhood autism
this paper tries to introduce it into the syndrome treatment of childhood autism. Through divergent thinking of the same treatment of different diseases and the holistic concept in traditional Chinese medicine(TCM)
it is proposed here that the pathogenesis of childhood autism is kidney yin and essence deficiency
and the disease is located in the brain
and related to the heart
liver
spleen and kidney. Qian Yi created
Liuwei Dihuang
Pill on the basis of
Shenqi
Pill to treat children’s diseases related to kidney timidity.According to the pathogenesis of childhood autism combined with the analysis of Qian Yi
Liuwei Dihuang
Pill
this paper analyzed and discussed the treatment for childhood autism
increasing our understanding of childhood autism from the perspective of TCM and in the hope of bringing therapies closer to clinical application and finding practical and effective treatment methods for this disorder to explore the methods of TCM treatment of autism.
American Psychiatric Association . Diagnostic and statistical manual of mental disorders, fifth edition, text revision [M]. Washington : American Psychiatric Association Publishing , 2022 : 218 .
杨友 , 金星明 . 美国精神障碍诊断和统计手册第五版对儿童孤独症谱系障碍诊治的影响 [J]. 中国儿童保健杂志 , 2015 , 23 ( 12 ): 1278 - 1280 .
ZHOU H , XU X , YAN WL , et al . Prevalence of Autism Spectrum Disorder in China: A Nationwide Multi-center Population-based Study Among Children Aged 6 to 12 Years [J]. Neurosci Bull , 2020 , 36 ( 9 ): 961 - 971 .
HIROTA T , KING BH . Autism Spectrum Disorder: A Review [J]. JAMA , 2023 , 329 ( 2 ): 157 - 168 .
陆超元 , 赵鋆 . 唐为勇辨治小儿自闭症经验 [J]. 上海中医药杂志 , 2012 , 46 ( 8 ): 23 - 24 .
唐艳鹏 , 王晓聪 , 张莎莎 , 等 . 王素梅教授从脾肾不足论治小儿自闭症经验 [J]. 现代中西医结合杂志 , 2021 , 30 ( 23 ): 2572 - 2575 .
魏槃 , 付国兵 , 戴晓晖 . 从“五脏藏神”论振腹推拿治疗小儿自闭症 [J]. 环球中医药 , 2020 , 13 ( 1 ): 77 - 79 .
钱乙 . 小儿药证直诀 [M]. 北京 : 人民卫生出版社 , 2006 .
MANOLI DS , STATE MW . Autism Spectrum Disorder Genetics and the Search for Pathological Mechanisms [J]. Am J Psychiatry , 2021 , 178 ( 1 ): 30 - 38 .
胥利娟 . 浅谈小儿自闭症的病因症状及干预措施 [J]. 医药前沿 , 2015 ( 34 ): 63 - 64 .
朱力立 , 陈栋 , 张怡颖 , 等 . 基于肠道菌群理论探讨针刺在孤独症谱系障碍中的作用机制 [J]. 上海针灸杂志 , 2020 , 39 ( 10 ): 1351 - 1356 .
KWON CS , WIRRELL EC , JETTÉ N . Autism Spectrum Disorder and Epilepsy [J]. Neurol Clin , 2022 , 40 ( 4 ): 831 - 847 .
MCWILLIAMS A , REILLY C , GUPTA J , et al . Autism spectrum disorder in children and young people with non-epileptic seizures [J]. Seizure , 2019 , 73 : 51 - 55 .
ZHANG YH , XIANG Z , JIA YJ , et al . The Notch signaling pathway inhibitor Dapt alleviates autism-like behavior, autophagy and dendritic spine density abnormalities in a valproic acid-induced animal model of autism [J/OL]. Prog Neuropsychopharmacol Biol Psychiatry , 2019 , 94 : 109644 [ 2023-04-10 ]. https://www.sciencedirect.com/science/article/abs/pii/S0278584618308212?via%3Dihub .
PAGANI M , BARSOTTI N , BERTERO A , et al . mTOR-related synaptic pathology causes autism spectrum disorder-associated functional hyperconnectivity [J/OL]. Nat Commun , 2021 , 12 ( 1 ): 6084 [ 2023-04-10 ]. https://www.nature.com/articles/s41467-021-26131-z .
CARACCI MO , AVILA ME , ESPINOZA-CAVIERES FA , et al . Wnt/β-Catenin-Dependent Transcription in Autism Spectrum Disorders [J/OL]. Front Mol Neurosci , 2021 , 14 : 764756 [ 2023-04-10 ]. https://www.frontiersin.org/articles/10.3389/fnmol.2021.764756/full .
陈思刚 , 陈鲁 . 浅议小儿“肾常虚” [J]. 中国民间疗法 , 2021 , 29 ( 3 ): 4 - 5 .
宋璞 . 孕期环境因素对儿童孤独症影响的临床研究 [D]. 大连 : 大连医科大学 , 2020 .
李帅 , 张启明 . 肾为先天之本的历史轨迹 [J]. 世界最新医学信息文摘 , 2019 , 19 ( 35 ): 216 - 217 .
孙帅帅 . 六味地黄丸在老年痴呆症辅佐治疗中的应用效果 [J]. 中国医药指南 , 2020 , 18 ( 21 ): 169 - 170 .
吴玉晶 , 晏雨军 , 徐荣谦 . 六味地黄汤治疗小儿脑发育迟缓1例报道 [J]. 中国中西医结合儿科学 , 2013 , 5 ( 6 ): 574 - 575 .
赵任杰 , 王学明 , 陈芳民 , 等 . 六味地黄丸治疗小儿脑瘫的疗效及其基于网络药理学的机制研究 [J]. 世界科学技术—中医药现代化 , 2022 , 24 ( 6 ): 2283 - 2293 .
贾亚泉 , 宋军营 , 曾华辉 , 等 . 六味地黄丸和通络救脑滴丸对2种痴呆模型小鼠脑组织Aβ降解的影响 [J]. 世界中医药 , 2023 , 18 ( 14 ): 1966 - 1973 .
ZHOU WX , CHENG XR , ZHANG YX . Effect of Liuwei Dihuang decoction, a traditional Chinese medicinal prescription, on the neuroendocrine immunomodulation network [J]. Pharmacol Ther , 2016 , 162 : 170 - 178 .
0
Views
213
下载量
0
CSCD
Publicity Resources
Related Articles
Related Author
Related Institution
京公网安备11010802024621