Exploring the characteristics of six climatic exopathogens causing intestinal flora dysregulation based on etiological theory

WANG Yuhua; LIANG Xiaoyan; CHEN Haoyu; REN Xuetong; YANG Tianxiao; LIU Shaowei; WANG Yangang

doi:10.3969/j.issn.1006-2157.2023.12.006

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Exploring the characteristics of six climatic exopathogens causing intestinal flora dysregulation based on etiological theory

Theoretical Studies | 更新时间：2024-01-03

- Exploring the characteristics of six climatic exopathogens causing intestinal flora dysregulation based on etiological theory
- Journal of Beijing University of Traditional Chinese Medicine Vol. 46, Issue 12, Pages: 1658-1664(2023)
- 作者机构：
  
  1.河北中医药大学第一附属医院　石家庄　050091
  2.广州中医药大学第八临床医学院
  3.北京中医药大学第三附属医院
- 作者简介：
  
  Prof.WANG Yangang, Ph. D., Chief Physician, Doctoral Supervisor. Beijing University of Chinese Medicine Third Affiliated Hospital, No.51, Xiaoguan Street, Qutside Anding Gate, Chaoyang District, Beijing, 100029. E-mail: piwei001@163.com
- 基金信息：
  
  Hebei Province Natural Science Foundation of China(H2020423207);Beijing Natural Science Foundation of China(7232281);Scientific research project of Hebei Provincial Administration of Traditional Chinese Medicine(2024097;2024012)
- DOI：10.3969/j.issn.1006-2157.2023.12.006
  CLC： R223
- Received：03 July 2023，
  
  Published Online：26 October 2023，
  
  Published：30 December 2023
- 稿件说明：
移动端阅览
WANG Yuhua, LIANG Xiaoyan, CHEN Haoyu, et al. Exploring the characteristics of six climatic exopathogens causing intestinal flora dysregulation based on etiological theory[J]. Journal of beijing university of traditional chinese medicine, 2023, 46(12): 1658-1664.
DOI：

WANG Yuhua, LIANG Xiaoyan, CHEN Haoyu, et al. Exploring the characteristics of six climatic exopathogens causing intestinal flora dysregulation based on etiological theory[J]. Journal of beijing university of traditional chinese medicine, 2023, 46(12): 1658-1664. DOI： 10.3969/j.issn.1006-2157.2023.12.006.

摘要

肠道菌群与疾病之间的关系是目前的研究热点，但多倾向于对其因果关系及发病机制的阐述，尚缺乏病因学视角下肠道微生态紊乱的中医特色探讨，混杂菌群的中医致病特点亟待进一步厘清。肠道菌群是机体内部与外界环境沟通的重要桥梁，在疾病的诊断、预后、治疗中扮演重要且复杂的角色。本文基于中医病因学理论，从肠道微生态紊乱的基本概念、形成原因、致病性质与特点等方面，结合神经系统、免疫系统、腺体分泌及营养代谢理论，以临床表现为依据，运用审症求因的方法，探讨肠道微生态紊乱导致风、火、燥、湿、寒变化的科学内涵。希望本文能为肠道菌群的中医学研究提供新的思路，补充、丰富病因学说内容，同时为肠道微生态紊乱可以促进各种复杂疾病的发生、发展的理解与研究提供新的理论依据。

Abstract

The relationship between intestinal flora and diseases is currently a hot topic of research

but most studies tend to explain causality and pathogenesis

and there is still a lack of studies of the traditional Chinese medicine (TCM) characteristics of intestinal microecological disorders from the perspective of etiology. The TCM pathogenic characteristics of hybrid flora need to be further clarified. The intestinal flora is an important bridge between the internal and the external environment of body

and plays an important and complex role in the diagnosis

prognosis

and treatment of diseases. Based on the etiology theory of TCM

this paper discusses the scientific connotation of changes of wind

fire

dryness

dampness

and cold caused by intestinal microecological disorder from the aspects of basic concepts

formation causes

and pathogenic nature and characteristics

combined with the nervous system

immune system

gland secretion

and nutritional metabolism

based on clinical manifestations

using the method of examining symptoms and seeking causes. This paper provides a new idea for the study of intestinal flora in TCM

and supplements and enriches the theory of etiology. At the same time

it provides an innovative theoretical basis for the understanding and research that intestinal microecological disorders can promote the occurrence and development of various complex diseases.

关键词

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references

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