Mechanism of tall gastrodia tuber-rose root medicinal pair on the regulation of TNF-α/NF-κB to protect the endothelial cell barrier in mice with hypoperfused-cerebral small vessel disease model
Special Theme: TCM Prevention and Treatment of Cerebrovascular Diseases|更新时间:2024-06-03
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Mechanism of tall gastrodia tuber-rose root medicinal pair on the regulation of TNF-α/NF-κB to protect the endothelial cell barrier in mice with hypoperfused-cerebral small vessel disease model
“The latest research has found that the "Tianma Hongjingtian" medicine can increase cerebral blood flow, improve gait abnormalities, alleviate brain tissue pathological damage, and protect the function and structure of endothelial cell barrier in mice with hypoperfusion cerebral small vessel disease by regulating TNF - α/NF - κ B. Its mechanism may be related to reducing the expression of inflammatory factors.”
Journal of Beijing University of Traditional Chinese MedicineVol. 47, Issue 5, Pages: 611-624(2024)
作者机构:
1.首都医科大学中医药学院中医临床基础学学系 北京 100069
2.中医络病研究北京市重点实验室
3.首都医科大学基础医学院
作者简介:
Prof. ZHANG Qiuxia, Ph.D., Doctoral Supervisor.School of Traditional Chinese Medicine, Capital Medical University, No.10, You′anmen West, Fengtai District, Beijing 100069. E-mail: 20000005@ccmu.edu.cn
基金信息:
National Natural Science Foundation of China(81873224)
ZHANG Ying, CHENG Hongfa, LIU Shiqi, et al. Mechanism of tall gastrodia tuber-rose root medicinal pair on the regulation of TNF-α/NF-κB to protect the endothelial cell barrier in mice with hypoperfused-cerebral small vessel disease model[J]. Journal of beijing university of traditional chinese medicine, 2024, 47(5): 611-624.
DOI:
ZHANG Ying, CHENG Hongfa, LIU Shiqi, et al. Mechanism of tall gastrodia tuber-rose root medicinal pair on the regulation of TNF-α/NF-κB to protect the endothelial cell barrier in mice with hypoperfused-cerebral small vessel disease model[J]. Journal of beijing university of traditional chinese medicine, 2024, 47(5): 611-624. DOI: 10.3969/j.issn.1006-2157.2024.05.004.
Mechanism of tall gastrodia tuber-rose root medicinal pair on the regulation of TNF-α/NF-κB to protect the endothelial cell barrier in mice with hypoperfused-cerebral small vessel disease model
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