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Mechanism of tall gastrodia tuber-rose root medicinal pair on the regulation of TNF-α/NF-κB to protect the endothelial cell barrier in mice with hypoperfused-cerebral small vessel disease model
Special Theme: TCM Prevention and Treatment of Cerebrovascular Diseases | 更新时间:2024-06-03
    • Mechanism of tall gastrodia tuber-rose root medicinal pair on the regulation of TNF-α/NF-κB to protect the endothelial cell barrier in mice with hypoperfused-cerebral small vessel disease model

    • The latest research has found that the "Tianma Hongjingtian" medicine can increase cerebral blood flow, improve gait abnormalities, alleviate brain tissue pathological damage, and protect the function and structure of endothelial cell barrier in mice with hypoperfusion cerebral small vessel disease by regulating TNF - α/NF - κ B. Its mechanism may be related to reducing the expression of inflammatory factors.
    • Journal of Beijing University of Traditional Chinese Medicine   Vol. 47, Issue 5, Pages: 611-624(2024)
    • DOI:10.3969/j.issn.1006-2157.2024.05.004    

      CLC: R285.5
    • Received:12 December 2023

      Published Online:28 April 2024

      Published:30 May 2024

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  • ZHANG Ying, CHENG Hongfa, LIU Shiqi, et al. Mechanism of tall gastrodia tuber-rose root medicinal pair on the regulation of TNF-α/NF-κB to protect the endothelial cell barrier in mice with hypoperfused-cerebral small vessel disease model[J]. Journal of beijing university of traditional chinese medicine, 2024, 47(5): 611-624. DOI: 10.3969/j.issn.1006-2157.2024.05.004.

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