Exploring the seasonal onset of allergic diseases from the perspective of the " the spleen serves as the guard" theory

SHENG Yuhan; LI Yuhang; LIU Yuqing; TANG Yang; WANG Jiarou; ZHENG Fengjie

doi:10.3969/j.issn.1006-2157.2024.11.013

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Exploring the seasonal onset of allergic diseases from the perspective of the " the spleen serves as the guard" theory

Clinical Studies | 更新时间：2024-12-02

- Exploring the seasonal onset of allergic diseases from the perspective of the " the spleen serves as the guard" theory
- Journal of Beijing University of Traditional Chinese Medicine Vol. 47, Issue 11, Pages: 1585-1590(2024)
- 作者机构：
  
  1.北京中医药大学中医学院　北京　100029
  2.北京中医药大学第二临床医学院
- 作者简介：
  
  Prof. ZHENG Fengjie, Ph. D., Doctoral Supervisor. School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, No.11 Beisanhuan Donglu Road, Chaoyang District, Beijing 100029. E-mail: zhengfengjie@bucm.edu.cn
- 基金信息：
  
  National Natural Science Foundation of China(82374321)
- DOI：10.3969/j.issn.1006-2157.2024.11.013
  CLC： R229
- Received：02 April 2024，
  
  Published Online：12 October 2024，
  
  Published：30 November 2024
- 稿件说明：
移动端阅览
SHENG Yuhan, LI Yuhang, LIU Yuqing, et al. Exploring the seasonal onset of allergic diseases from the perspective of the " the spleen serves as the guard" theory[J]. Journal of beijing university of traditional chinese medicine, 2024, 47(11): 1585-1590.
DOI：

SHENG Yuhan, LI Yuhang, LIU Yuqing, et al. Exploring the seasonal onset of allergic diseases from the perspective of the " the spleen serves as the guard" theory[J]. Journal of beijing university of traditional chinese medicine, 2024, 47(11): 1585-1590. DOI： 10.3969/j.issn.1006-2157.2024.11.013.

摘要

人禀天地之气生，人体生理病理功能受四时寒暑更替的影响。流行病学显示过敏性疾病常于季节交替时发作或加重，这与中医学“脾主四时之末”理论对应。脾功能失调导致季节交替时机体的时间自稳系统被破坏而无法适应外界气候变化，是引发或加重某些过敏性症状的内在原因。“脾为之卫”理论起源于《黄帝内经》，是对脾防御外邪、护卫机体功能的高度概括，强调脾在内运化水谷以补足正气、在外调控卫气以护卫周身，与人体免疫功能的季节性变化有密切联系，从而影响过敏性疾病的季节性发作。本文从“脾为之卫”探讨脾在过敏性疾病季节性发作中发挥的时间自稳和免疫防御功能，提出“脾为之卫”功能失调引发营卫失调、痰湿内生、五脏六腑失养等是过敏性疾病在季节交替时反复发作、迁延难愈的重要原因，为探索过敏性疾病季节性发作的机制与防治提供思路与启发。

Abstract

Humans are born under the nourishment of heaven and earth qi. The physiological and pathological functions of the human body are influenced by the alternation of cold and heat in the four seasons. Allergic diseases often occur or worsen during seasonal transitions

corresponding to the theory of the spleen dominating the end of the four seasons in traditional Chinese medicine. Splenic dysfunction disrupts the body′s internal clock during seasonal transitions

making it unable to adapt to external climate changes

causing the onset or exacerbation of specific allergic symptoms. The theory of " the spleen serves as the guard" originated from

Huangdi Neijing

which is a succinct summary of the role of the spleen in defending the body against external pathogens. The theory emphasizes that the spleen transports drinks and foods internally to supplement healthy qi

and regulates defensive qi externally to protect the whole body. This theory is closely linked to the seasonal changes in immune function

thereby influencing the seasonal onset of allergic diseases. This paper explores the roles of the spleen in time-based self-regulation and immune defense against seasonal allergic diseases according to the theory of " spleen serves as the grard." The dysfunction of this protective mechanism

which leads to disharmony in nutritive qi and defensive qi

internal production of phlegm-dampness

and zang-fu organs malnutrition

are the key factors causing recurrent and persistent allergic diseases during seasonal transitions. This study provides insights for elucidating the mechanisms behind seasonal allergic disease outbreaks and their prevention.

关键词

Keywords

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