Effect of Zuogui Jiangtang Jieyu Formula on hippocampal H3K18la modification in a rat model of diabetes mellitus complicated with depression and prediction of related regulatory genes
Experimental Study|更新时间:2025-07-01
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Effect of Zuogui Jiangtang Jieyu Formula on hippocampal H3K18la modification in a rat model of diabetes mellitus complicated with depression and prediction of related regulatory genes
“The latest research found that Zuogui Jiangtang Jieyu Recipe can increase the content of lactic acid in the hippocampus of rats with diabetes and depression, and increase the level of H3K18la, which may affect the process of neural cell interaction, neural stem cell function regulation and other processes.”
Journal of Beijing University of Traditional Chinese MedicineVol. 48, Issue 6, Pages: 791-801(2025)
作者机构:
1.湖南中医药大学第一附属医院 长沙 410007
2.湖南省中医药研究院附属医院
3.湖南中医药大学科技创新中心
作者简介:
Prof. WANG Yuhong, Ph.D., Doctoral Supervisor. Hunan University of Chinese Medicine, No.300, Bachelor Road, Hanpu Science and Education Park, Yuelu District, Changsha 410208. E-mail: wyh107@126.com
基金信息:
National Natural Science Foundation of China(82474476;82104839)
YANG Hui, LI Wei, LEI Shihui, et al. Effect of Zuogui Jiangtang Jieyu Formula on hippocampal H3K18la modification in a rat model of diabetes mellitus complicated with depression and prediction of related regulatory genes[J]. Journal of beijing university of traditional chinese medicine, 2025, 48(6): 791-801.
DOI:
YANG Hui, LI Wei, LEI Shihui, et al. Effect of Zuogui Jiangtang Jieyu Formula on hippocampal H3K18la modification in a rat model of diabetes mellitus complicated with depression and prediction of related regulatory genes[J]. Journal of beijing university of traditional chinese medicine, 2025, 48(6): 791-801. DOI: 10.3969/j.issn.1006-2157.2025.06.009.
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