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Effects and mechanism of the Tiansui Tongluo Formula in treating cerebral small vessel disease model rats by regulating miR-143-3p/NRG-1 axis
Experimental Studies | 更新时间：2026-03-03

    • Effects and mechanism of the Tiansui Tongluo Formula in treating cerebral small vessel disease model rats by regulating miR-143-3p/NRG-1 axis

    • “The formula for filling marrow and unblocking collaterals may alleviate hippocampal neuronal cell damage, inhibit cell apoptosis, and reduce neuronal loss by regulating the miR-143-3p/NRG-1 axis and its downstream PI3K/Akt signaling pathway, thereby improving cognitive impairment in CSVD rats”
    • Journal of Beijing University of Traditional Chinese Medicine   Vol. 49, Issue 2, Pages: 217-230(2026)

    • DOI：10.3969/j.issn.1006-2157.2026.02.008    

      CLC： R285.5

    • Received：09 October 2025，

      Accepted：04 February 2026，

      Published：2026-02

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  • LIU Yuxuan, GUAN Dongsheng, ZHAO Huanghong. Effects and mechanism of the Tiansui Tongluo Formula in treating cerebral small vessel disease model rats by regulating miR-143-3p/NRG-1 axis[J]. Journal of Beijing University of Traditional Chinese Medicine, 2026, 49(2): 217-230. DOI： 10.3969/j.issn.1006-2157.2026.02.008.

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