“Rheumatoid arthritis (RA) is an autoimmune inflammatory disease that belongs to the category of "Bi syndrome" in traditional Chinese medicine. The joint pain, bone destruction, and multi system damage caused by RA pose a serious threat to the health of patients. Our team, based on the characteristics of the disease, combines the theory of "suppressing evil" with the theory of targeted treatment to divide RA into four stages: emitting evil, spreading evil, latent evil, and chronic evil. We analyze the evolution of the disease mechanism, anchor the treatment difficulties of recurrent attacks and difficult cure, and provide new ideas for the overall diagnosis and treatment of RA, forming a general principle for RA treatment that supports normal qi, disperses cold and dampness, clears blood stasis and heat, and promotes meridians. Our team summarizes the clinical manifestations of RA into five states: deficiency, cold, dampness, heat, and blood stasis. Guizhi Shaoyao Zhimu Tang is used as the main prescription for the disease target. On the basis of staged treatment, the most prominent state of the patient is added and modified, and target drugs targeting symptoms, physical and chemical indicators, and imaging targets are added to construct a staged and targeted RA diagnosis and treatment system to improve the clinical level of traditional Chinese medicine diagnosis and treatment of RA. Rewrite: Rheumatoid arthritis (RA) is an autoimmune inflammatory disease that belongs to the category of "Bi syndrome" in traditional Chinese medicine. The joint pain, bone destruction, and multi system damage caused by RA pose a serious threat to the health of patients. Our team, based on the characteristics of the disease, combines the theory of "suppressing evil" with the theory of targeted treatment to divide RA into four stages: emitting evil, spreading evil, latent evil, and chronic evil. We analyze the evolution of the disease mechanism, anchor the treatment difficulties of recurrent attacks and difficult cure, and provide new ideas for the overall diagnosis and treatment of RA, forming a general principle for RA treatment that supports normal qi, disperses cold and dampness, clears blood stasis and heat, and promotes meridians. Our team summarizes the clinical manifestations of RA into five states: deficiency, cold, dampness, heat, and blood stasis. Guizhi Shaoyao Zhimu Tang is used as the main prescription for the disease target. On the basis of staged treatment, the most prominent state of the patient is added and modified, and target drugs targeting symptoms, physical and chemical indicators, and imaging targets are added to construct a staged and targeted RA diagnosis and treatment system to improve the clinical level of traditional Chinese medicine diagnosis and treatment of RA.”