摘要:The author commented on the history, status quo and tendency of development in Pharmaclogy of Traditional Chinese Medical Formulae.It was indicated that the traditional academic mode is on going to modern formulae study mode with the achievements in many aspects of formulae which is Characterized by aiming at development of new drugs based on the theory of TCM with the help of computer & experimental method. The new formulae study is to demonstrate the mechanism of efficacy of ancient and modem formulae,to illustrate the reason of making prescription up and regular rule of applying formulae in clinic. Formulae study is facing on urgent problems to be resolved such as accelerating development in academic area, regulating specialty direction, extending the research to the region of practice and so on.
摘要:From syndrome,disease name,pathogenic factor and pathogenesis, treatment rules and drugs most in use,the author have discussed the current situation. advantages and problems of the research on prevention and treatment of myelodysplastic syndromes (MDS) with TCM.They suggested that these research works should be conducted with TCM theory and united with other associated disciplines. Based on the studies Of epidemic investigation of MDS,the pathogenic factor I pathogenesis and rules of differentiation of signs and symptom and treatment should be discussed. A clinical curative criterion,which would be confirmed with TCM, should be established, so that the research of MDS with TCM could be standardized. They thought it might be a penetrating point of research on MDS with TCM to establish animal model of MDS, improve the morbid hematopoiesis of marrow megakaryocytic series of these patients and increase their peripheral platelet numbers.
关键词:Myeledysplastic syndromes (MDS);TCM;Pathogenic factor and pathogenesis;Syndrome name;Treatment rules;Drug most in use;criterion of therapeutic effect;Epidemic investigation.
摘要:With immunohistochemical method, the influence of Xiaopiling Granule (XPL) on thechanges of Carcinoembruonic Antigen (CEA) of gastric mocosal S-100 positive cells of gastric mucosa and spleen in rat with gastric precancerous lesion (GPL) were observed. The results showed that the positive expression of CEA in gastric mucosa, the positive cell numbers of S-100 in gastric mucosa and spleen in pathological groups were found significantly higher than those of the control groups. The above mentioned indices were significantly decreased after prevented and treated with GPL. The results indicated that XPL could inhibit the expression of tumor associated antigen of GPL and influence the immune function of the body, and this might be one of the ways of XPL’s prevention and treatment effects on GPL.
摘要:In vitro, the antitumor effects of 6 alkaloids isolated from the seed of Sophora viciifolia on 11 kinds of human being tumor strains has been reported. The results showed that these kinds of alkaloids have stronger inhibiting effects on leukemia strain and a certain effect on epidermis tumor strain, mean while, these effects also have a better selectivity.
关键词:Sophora viciifolia;alkaloids;Antitumor effect;Human being tumor strain
摘要:Testing serum aPOA-1, aPOB of 93 cases with chronic viral hepatitis B. The results showed: The average level of serum aPOA-1, aPOB in all those patients were below normal, especially in patients with chronic active hepatitis B. According to TCM differemtoatopm of syndromes and types,the average level of serum aPOA-1, aPOB from low to high orderly was: the type of deficiency of liver -Yin and kidney -Yin; blood stasis in Luo Mat (collateral branch of the large channel); staganation of the liver -qi and deficiency of the spleen as well as the type of dampness and heat in the liver and the gallbladder. aPOA-1/aPOB in patients with chronic active hepatitis B and patients belonged to the type of deficiency of liver-yin and kidney Yin were obviously abnormal.