摘要:Pathomorphological lesions of the liver of endotoxin shock rats were studied with light and electron microscopy and quantitative analaysis of hepatic mitochondria. Light microscopic Iesions of the endotoxin shock group included the hepatic sinusoidal lumina and central vein dilation,blood stasis and leucocyte accuxnulation,and hepatic cell swelling,acidophilic change and even karyorrhexis. Electron microscopy revealed severe hepatocytic damages including karyopyknosis, mitochondria swelling and degeneration,dilation of endoplasmic reticulum, depletion of glycogen, etc.The results of quantitative analysis of mitochondria showed that the number density and surface density, the ratio Of surface area and volume of mitochondria were much reduced, compared with those in the normal control group, and the mean surface area and volume of mitochondria in the endotoxin shock group were much increased, with those in the normal control group.The Xinmailing Solution treatment group conformed with the normal control group concerning the above-mentioned results.The results suggest that Xinmailing Solution may play a role in preventing rats form liver injury caused by endotoxin shock.
摘要:The effects of Zhuyuhuatan Decoction,Sansheng Decoction and Didang Decoction on the frequency,wave amplitude and θindex in different phases of EEG were observed through the rat disease model induced by intracophalic blood infusion.The results showed that the extent of resisting ischemia and hypoxia of 3 drug-given coups was obviously greater than that of the normal saline-given model group.Concerning the effects on the frequency and wave amplitude,Sansheng Decoction and Zhuyuhuatan Decoction were better than Didang Decoctionwhile concerning the effect on the θindex,Zhuyuhuatan Decoction was better than Didang Decoction and SanshengDecoction.
摘要:on the basis of quantitative determination of LDH, MDH, G-6-PDH, AcP,ANAE, -SH and RNA in the epithelial cells of 7 common tongue coatings found in 117 patients, models for quantitative diagnosis were created by multivariate stepwise regression method,concerning the normal white thin,deficiency-cold White thin,deficiencycold white thick,yellow thin,yellow thick,partially missing,and entirely missing tongue coatings.The results of clinical tests of these models showed that the sensitivity was 93.2%,specificity was 81.4%,accuracy was 87.2%,and practicability was 75.7%
关键词:Diagnostic examination of the Tongue;tongue coating;Quantitative Diagnosis;Cytochemistry
摘要:This article reviews the modern experimental studies of physiology and pathology of the liver in TCM concepts,including the following respects: understanding of the liver,differentiation of the common liver syndromes,studies Of TCM liver diseases,and prospect of liver disease studies.There are some similarities and differences between TCM and Western medicine in understanding the liver.The modern medical techniques should combine with unique traditional Chinese ones,and medical workers should pay attention both to molecular and ultrastructural pathology of the liver and the traditional Chinese concepts about liver diseases.If so,the treatment of liver diseases will surely achieve better results.
摘要:Protective effects of Xingnaojianshen Capsules,Zhongfengnaodeping Granules and Qingkailing Injection on hippocampal neuron of the stroke-prone and spontaneously hypertensive rats(SHRsp)were observed and excitatory amino acids(EAA),Ca2+ content, neuronal density and ultrastructural changes were measured.The results showed that in the pathologic group the neuronal density of hippocamp was markedly decreased, hippocamp was with marked edema,cell internal organs were decreased in number and edematous,EAA content was increased and Ca2+ content was decreased, compared with the control group.Again,the results showed that in the treatment groups the neuronal density was increased, ultrastructural neuronal denaturation and necrosis were improved,the increase of EAA content and decrease of Ca2+ content were corrected.The intensity of protective effects of the drugs used in the treatment groups was:Xingnaojianshen Capsules>Qingkailing Injection>Zhongfengnaodeping Granules.
摘要:cases of cephalic wind syndrome were treated by the therapy of tranquilizing wind and removin stagnation.The total effective rate was 95.37% and the markedly effective rate was 77.78%.The author holds that the syndrome is due to liver wind and blood stasis with phlegm-fire or with cold-damp which block the encephalic orifices and lead to the obstruction of encephalic channels and collaterals The treating strategies should be tranquilizing wind and removing stagnation,along with the treatment of clearing heat and phlegm,and warming and removing cold and dampness.
关键词:Cephalic Wind;Angioneurotic Headache;Therapy of Removing Wind and Phlegm;Liver Wind;Blood Stasis
摘要:cases of nephrotic syndrome were divided into TCM drug plus hormone group and TCM drug alone group.The main symptoms and the criteria of urinary protein,blood creatinine,endogenous creatinine clearance rate and urea nitrogen of the two groups were observed before and after the treatment.The results showed that in the TCM drug plus hormone group,the symptoms of 49% of the patients were entirely relieved or generally relieved and the total effective rate was 90.7%.The author holds that although TCM drugs plus hormone are effective for treating nephrotic syndrome,to find the TCM drugs in a shorter time which can substitute for the hormone used in the treatment is an important subject to study at present.
关键词:Nephrotic Syndrome;TCM diagnosis and Treating Strategies;TCM Drugs;Prednisone