最新刊期
卷 0 ， 期 0 ， 2020
- 摘要：The studies of the integration of traditional Chinese and Western medicines （ITCWM） have made much headway. In the ITCWM practice the treatment of tumors, cardio cerebrovascular diseases, hematopathy, gynecopathy, pediatric diseases and surgical diseases has achieved satisfactory curative effects. In ITCWM experimental research field the animal models of various kinds of disease and TCM syndrome have been developed in order to understand the treating mechanisms of traditional Chinese drugs （TCD） and the pathogenic basis of TCM syndromes; the studies of TCD pharmacology have been carried out by the the methods of combining clinical pharmacology and experimental pharmacology and of combining the chemistry of all ingredients in a prescription and the chemistry of a single ingredient in the prescription,and by doing so, the innovation of TCD basic theory has been promoted.The author holds that, from now on, ITCWM clinical practice should carry out programs on the mutual supplement of diagnostic differentiation of TCM syndromes and diagnostic differentiation of diseases, on the establishment of microscopic criteria for macroscopic diagnostic differentiation of TCM syndroms, and on the application of the microscopic criteria under the guidance of the TCM concept of wholism. The author also holds that still deeper studies of basic TCM theories should be launched by fully utilizing modern scientific techniques and strengthening laboratory work.关键词：Integration of Traditional Chinese and Western Medicines;clinical study;Experimental Study;Traditional Chinese Drugs Study
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发布时间：2021-09-15 -
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- 摘要：Japan white rabbits were fed on l gram of cholesterol and 4 grams of lard per day for 2 months to induce atherosclerosis, Baoxin pills group was simultaneously given Baoxin pills 8 grams per kilogram of body weight, and the control group was given Gemfibrozil 80 milligrams per kilogram of body weight. The contents of blood lipid, apolipoprotein and lipid peroxide were determined in each phase of the experiment and rabbit aortas were stained with hematoxylin, oil red 0 and by a special stain method. The results showed that Baoxin pills could significantly lower serum TC, LDL c, TG, atherogenic index and apolipoprotein B 100 , increase the rates of HDL c/TC, and HDL c/LDL c, and significantly lower plasma LPO content. Pathological observation showed that Baoxin pills could protect vascular endothelial cells, inhibit proliferation and migration of smooth muscle cells, and reduce the formation of elastic fibers and collageneous fibers in media, which therefore evidently decreased atherosclerotic plaque area. The key of Baoxin pills in regulating blood lipid metabolism was lowering LDL c. The lowering of LDL c and LPO contents caused the decrease of oxidized LDL and MDA LDL, and therefore inhibited the development of atherosclerosis. Gemfibrozil could significantly decrease TC and increase apolipoprotein A 1, but had no any influences on other biological substances.关键词：Baoxin Pills;Gemfibrozil;atherosclerosis;blood lipid;Apolipoprotein;Lipid Peroxide;Rabbit
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发布时间：2021-09-15 - 摘要：The preventive and curative effects of Yishen Daozhuo oral solution on rat chronic renal failure model induced by adenine were observed. The results showed that this oral solution not only alleviated the symptoms of renal failure but also improved renal function and relieved hyperphospho hypocalcemia. After the treatment of the oral solution it was found that the intrarenal crystalline deposit evidently reduced,the appearance of some renal tubules became nearly normal, and there was an obvious protective effect on renal tubular mitochondria, and a promotive effect on renal tubular epithelial cell regeneration. The results suggested that the oral solution was markedly effective in the treatment of rat chronic renal failure and the curative effect was better than verapamil.关键词：Yishen Daozhuo Oral Solution;Disease Model Induced by Adenine;chronic renal failure;Renal Morphology;rat
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发布时间：2021-09-15 - 摘要：The experimental cerebral hematoma model was induced by injecting autogenous clot into rats. The influences of Zhongfeng Naodeping granules on cerebral index,the contents of water, Na +, K +,Ca 2+ and Mg 2+ of the brain tissue, and the cerebrovascular permeability, in 6 h, 12 h, 48 h, and 72 h after the induction of cerebral hematoma, were observed, and the results showed that in the model group, the cerebral index and the contents of water and Na + of the brain tissue had a progressive increase, and the cerebrovascular permeability, especially that of the right side of the brain （with hematoma） became evidently enhanced; Zhongfeng Naodeping granules could alleviate cerebral edema, and reduce cerebral index, the contents of water and Na + of the brain tissue, and lessen the cerebrovascular permeability. The results of the research suggest that Zhongfeng Naodeping granules are useful in the treatment of encephaledema induced by experimental cerebral hematoma.
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发布时间：2021-09-15 - 摘要：The methods used in experiments on behavioral genetics were adopted in this study,and the behavioral heredity was studied by using the microscopic criteria established for studying cerebral morphology. The model of renal damage by terror was induced by using a cat to threaten pregnant mice .The primary mice produced by the model group were compared with those produced by the control group, and the results showed that in the mice of the model group, the cerebral cortex was much thinner; in addition, the number of neurons of cerebral cortex showed a decrease of 10% with a decreased number of dendrites. These finds can be used as criteria for studying the TCM theory that terror damages the kidney and the kidney connects the brain on the basis of behavioral genetics.关键词：Kidney;Behavioral Genetics;Theory that Terror Damages the Kidney;Cerebral Cortex;Neuron
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发布时间：2021-09-15 - 摘要：The model of rat acute blood stasis （ABS） was induced with adrenaline and ice bath. The effects of Ephedra Sinica （ES）, Prunlla Vulgaris （PV） and cuttlefish bone （CB） on PT, ELT and hemorrheologic criteria were observed in ABS rats. The results showed that compared with those of ABS model group, the PT of ES and PV groups was prolonged （P<0.01）, and ELT of the two groups was shortened （P<0.05）; ES could decrease the blood viscosity and improve hemorrheologic criteria markedly, PV could only improve part of hemorrheologic criteria, and CB had no any effects on all the above mentioned criteria.关键词：Ephedra Sinica;Prunlla Vulgaris;Cuttlefish Bone;blood stasis;hemorrheology
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发布时间：2021-09-15 -
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