最新刊期
卷 0 ， 期 4 ， 1997
- 摘要：Vascular dementia （VD） is the Second commonest dementia after Alzheimer’s disease （AD） inEurope and USA. However, in Asia and many developing countries the Prevalence of VD exceeds that of AD. Epidemiological studies show that the prevalence of VD increases linearly with age and varies greatly from Country tocountry, ranging form 1.2% to 4.2% of people over 65 years old, even after adjustment for age and sex. The incidence of VD is more homogeneous than prevalence and is estimated at 6 12 cases per 1, 000 persons over 70 yearsper year. The mean duration of the disease is around 5 years and survival is less than for the general population andfor AD. The major risk factors for VD appear to be hypertension, diabetes, heart disease and stroke. Although someof these risk factors are modifiable, there is no study on the efficacy of prevention of VD. VD may be caed bymultiple infarcts, white matter ischemia, or a infarct in a strategical place. The site, size, number, and frequency ofcerebral infarct or lesion are relative to prevalence rate of VD. Evidence of focal neurological deficit on examinationand cerebrovascular disease on computed tomography or magnetic resonance imaging is helpful to determine diagnosisand differentiation of VD. Cognitive neuropsychological assessment is helpful to diagnose and differentiate AD andother types of dementia. The simultaneous determination of Ach and Ch concentrations in cerebrospinal fluid may beuseful for differentiating vascular dementia of the Binswanger type or multiple small infarct type from Alzheimer typedementia. The frequency of the ApoE epsilon 4 allele is significantly higher in the patients with AD and VD, but issighficantly different in the cerebrovascular disease without dementia; the skin fibroblast ApoE mRNA level in theAD and VD Patients is significantly lower than in control group, which indicates that ApoE4 allele and ApoE mRNAlevel might be of value for diagnosis of AD. All patients with possible VD need careful assessment to detect any underlying causes and risk factors that may be remediable. No breakout Progress of treatment is available until now.Early hopes that calcium channel blockers such as nimodipine would be of value have not been sustained. Several further strategies──for example, to protect neurones from excitoxins or reinforce other neuroprotective mechanisms──are under further evaluation, but it is too early to be certain of their potential in the clinical context.
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发布时间：2021-09-15 - 摘要：In TCM, the thoughts on doing researches shold not be only focused on diseases because TCMalways holds a holistic concept and takes patients as holistic superior organisms; the correspondence between formulas and syndromes, and between drugs and syndromes should be emphasized; if it is difficult to make breathroughsin researches on TCM theoretical aspect, the priority of TCM research should be turned to the verification of clincaleffects; it would be more practical to put equal emphases on both tradional Chinese and Western medicines.关键词：traditional Chinese medicine;Thought on hong Researches;holism;Correspondence Between Formulas and Syndromes;Correspondence Between Drugs and Syndromes;curative effect;Equal Emphaseson both Traditional Chinese and Western Medicines
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发布时间：2021-09-15 -
- 摘要：The author has made a literary research on the TCM term jingqi and points out that in ancientChinese philosophy, jingqi is used to stand for qi which is considered the origin of the universe, and the term is alsoused to stand for the essential part of qi, which is considered the origin of the mankind. In TCM, however, jingqi isused to stand for the vital essence including congenital and acquired vital substances;jingqi is different from qi whichis considered a kind of kinetic essential vital substance. TCM holds that the vital essence is the origin of qi and qi isthe functional reflection of the vital essence. Finally. the author said that although the definition of jingqi in TCM isdifferent from that in ancient Chinese philosophy, there is a certain relationship between them.关键词：Jingqi;Vital Essence;qi;Ancient Chinese Philosophy;traditional Chinese medicine;Doctrine of Five Zang-organs, Jingqi and Yin-Yang
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发布时间：2021-09-15 -
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- 摘要：By using the method of treadmill （with the slope at 0 degree） exercise with a long term （totally7 weeks） and high intensity （the speed was from 15 m/min gradually increased to 35 m/min, and the time was 20to 25 min/d）, the fatigue model was replicated in order to observe the changes of blood opioid peptides and to findout the therapeutic machanism of Tifukang. The results showed that blood lacate level of model group was significantly higher than that of control group, while the levels of plasma beta-endorphin and dynorphin A1-13 were obviously lower, without remarkable change of leucine-enkephalin level. Under the treatment of Tifukang, the abovecriteria were normalized in different degrees. This implies that the endogenous opioid peptides system of the fatiguerat was inhibited by such intensity of exercise, while Tifukang could activate the system and increase plasma betaendorphin level and eliminate blood lactate, which results in recovery from fatigue.
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发布时间：2021-09-15 -
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- 摘要：134 Patients of diabetic peripheral nervous lesion were randomly divided into treating group treated with Tangluoning Oral Solution （TOS）. and control group treated with Jisheng Shenqi Pills （JSP）. After 1course of treatment, the results showed that the marked effective rate of the treating group was 55.88% and theoverall effective rate was 93.14 %; the marked effective rate of the control group was 21.86% and the overall effective rate was 59.37%; and difference between the two groups was significant （P<0.05）. The results also showedthat TOS was better than JSP in reducing the symptoms such as limb numbness, melagra and muscular weakness;and TOS could, in different degrees, normalize certain laboratory criteria used in clinical observation on the diseaseswithout any toxic and side effects.
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发布时间：2021-09-15 -
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