摘要:The protective effects of the Weishu Granular on the gastric mucosa of rats were observed and the mechanism of action was discussed. The results show that the Weishu Granular has a markedly protection on the gastric mucosa injury induced by the indometacin, acidic ethanol and water immersion-enchaining. The protection correlates with enhancing the ability of the gastric mucosa to clear the oxygen free radical. It has no significant effects on the gastric content and the gastric folds bound mucus.
摘要:Collateral System is the functional network to keep the entatic state of the body. Collateral disease is characterized by the stagnation of the system. Pathogen invasion of the collateral signalized the development and intensification of the disease, which is mainly expressed by the pathological changes of blood stasis, stagnation by deficiency and toxic factor. The research was started with the vascular dementia and diabetes vascular lesion. It was discovered that the pathologic changes of pathogen invasion in the blood or the collateral not only existed in choronic cases but also in emergency cases. One of the pathophysiologic bases of collateral disease was inferred as the endothelial and the interaction disturbance between blood vessel and blood constituents.
摘要:Liansu Zhi’ou Capsule administered to the digestive canal can reduce the vomiting frequency of Canis familiaris induced by L-Dopa and prolong the vomiting formation time. It has the same effect on the columpa livia domestica induced by copper sulfate. Also, it can promote the gastric emptying of rat, and have bacteriostatic activity to some degree.
摘要:cases (for standard) were chosen out of 120 000 random cases of discharged patients in 1994 from 88 TCM hospitals in China. 475 TCM diagnosis names were found. Further analysis showed the TCM data distribution of inpatients all over the country. It was found that the chart is related with the TCM distinct. It proved the rationality and importance to build special centers and hospitals for the TCM development.
摘要:From the steam distilled oils of Myosurus Elsholzia, 72 constituents were separated and identified by the gas chromatographmass spectrometercomputer (GCMSCOM) method. The main constituents are 1,8 cineole (45.31%), terpiene (12.95%), pinene (4.81%), pinene (3.31%), limonene (5.52%), etc.
摘要:A rat model of KidneyYang deficiency was created by injection with hydrocortisone acetate (HCA). Study the diuresis of Zhenwu Tang (ZW). Results show that, ZW can adjust the osmotic regulation point, decrease the secretion of antidiuretic hormone (ADH); and promote the excretion of K+, Na+ so to keep the normal level of the fluid and electrolyte contents. It can also antagonize the exogenetic glucocorticoid which inhibit the secretion of adrenal cortex, promote the aldosterone(ALD) secretion to keep the normal level of K+ and Na+. Further, the ZW can excite the inhibited hypothalamicpituitaryadrenocortical (HPA), increase the effective circulating blood volume and promote the secretion of atrial natriuretic polypeptide (ANP) till normal level. Finally, ZW remarkably improved the kidney function of HCA induced KidneyYang deficiency rat model. It improved the permeability of glomerular filtration membrane, promoted the excretion of metabolite like BCr, BUN, and forestalled the massive loss of pla
摘要:cases of vascular dementia(VD) were chosen according to the diagnostic criteria. By systematically TCM syndrome investigation and followup observation, three phases were found with the development of VD. They were stable, fluctuating and aggravating phase respectively. Further analysis showed that Kidney Deficiency, Phlegm Obstruction and Blood Stasis in the collateral were the pathological basis. And the core TCM mechanism of VD could be further injury and destruction of collateral and brain marrow by turbid or toxic pathogenic factor. The study suggested that differentiation of phases and syndrome played important role in the TCM treatment of VD.
摘要:Continuously perfuse the mice stomach with white spirit Er Guotou for 100 days. Observe the pathomorphology of the liver and stomach and discuss effects of the Soberup" Oral Fluid (SOF). Results show that, liver pathologic change of the ethanolised mice was in accordance with the pathomorphology of the human body. SOF has a remarkably benign effect on the hepatocyte diffuse fatty degeneration, inflamatory celluar infiltration and the pericentral venous fibroplastic proliferation. It also has a protective effect on the pathological damaged gastric mucosa.
摘要:Being enraged for 3 weeks and then coloclyster with 5% acetic acid, a rat model of ulcerative colitis with the Depression of Liverenergy and Asthenia of Spleen was created. Put the mice to death respectively after 3612 days and check the experimental index. The results show that: The body weight decreased with loose stool, the weight of adrenal body increased while that of thymus gland decreased; By the lightmicroscope the colonic mucosa was shown inflammatory infiltration, hemorrhage, edema and mucosal ulceration, etc. The multiplicative reaction of T, B lymphocytes was remarkably decreased and the blood viscosity (map.s) (45s-1, 18s-1 and 11.25s-1) level were significantly increase. After 12 days, the hypothalamic, monoamine hormone, like norepinephrine, dopamine and 5hydroxytryptamine, were remarkably increased. The changes of all the indexes above were more obviously than those only acetic acid induced colitis models. Further, improvement was achieved by treatment with TCM prescription of disperse the depressed liverenergy and invigorate the spleen.
关键词:Depression of liverenergy;ulcerative colitis;TCM syndrome of Depression of Liverenergy and Asthenia of Spleen;rat model;Disperse the depressed liverenergy and invigorate the spleen
摘要:Clinical data of 216 bileregurgitational gastritis (BRG) cases were completely retrospected. The analysis was started with the distinct of the onset, clinical symptoms, condition of the tongue and the pulse, gastroscopic image, pathology, etc. Results show that: The main TCM syndrome is the invasion of stomach by the pathogen of gallbladder, so the relative treatment should depend on relieving hyperactive gallbladderqi and regulate the stomach. The TCM name of BRG, Dandan, also was discussed on the TCM syndrome distinct, etiology and pathogenesis.
摘要:The effects of Hejiang Oral Solution (HOS) on the changes of the serum gastrin and PGE2 of bile reflux gastritis (BRG) in rats were discussed. The results showed that intragastric feeding of the HOS at the dosage of 12g/kg and 3g/kg (20 & 5 times of the clinical dosage respectively) for 30 days can increase gastric secretory and promote the recovery of inflammation.
摘要:The theory of attributive channel means the selective action of medicine on certain Zang and Fu organ and channel, i.e. agent or target organ. It mainly depends on the viscerastate and channel theory,which is guiding Principle of Chenese herbal medicine. Modern research has found the attributive channel theory has close relation with the effective constituents’ distribution in the body, the microelements of the herbal medicine, the Chinese medicine pharmacology and the receptor theory. Future experiments research of the attributive channel theary should be conducted with modern hightech, in addition to strengthening the theoretical research.
摘要:Examine thymus and spleen index of the mice models, determine thymocyte multiplication by 3 HTdR incorporation, and phagocytic function of celiac macrophage by neutralred colorimetric method. Then calculate the tumor inhibitory rate. Results: Compare the group of Astragalus S4 (AS) and cyclophosphamide with the control group of cyclophosphamide, significant difference was showed. Using AS alone can also promote thymocyte multiplication of the tumorigenic mice and have some inhibitory action, the rate was 35.78%. Conclusion: AS combined with chemotherapy drugs can ameliorate the immunological suppression by chemotherapy and have tumor inhibitory action.