摘要:cases (for standard) were chosen out of 120 000 random cases of discharged patients in 1994 from 88 TCM hospitals in China. 1 027 TCM syndrome diagnoses names were found by statistic analysis. By chart we listed in sequence the numbers of the cases occupied by each diagnosis, then got a representative distribution data of the in patients TCM syndrome diagnoses from representative TCM hospitals in China. This is significant for academic and clinical practice to promote the TCM development.
摘要:Based on the principle of “syndrom therapeutic method formulae drug” that are closely linked to each other and “ principal assistant adjuvant guiding(PAAG)”as guide of forming prescription,the rule of choosing or composing prescription clinically was revealed in accordance with main links of forming prescription such as diffrentiating syndrom, establishing therapeutic method, choosing and modifying set formulae, deliberating drugs and the dosages, from the facts of applying set formulae in clinic. Choosing prescription directlly is conditioned by consiliency of pathogenesis between what indicated in the set formulae and the syndrom of present disease while based on principle of forming prescription such as PAAG and the experience about combining various drugs. It is very necessary for a doctor to recognize pathogenesis of set formula indication, especially progressive pattern of disease and latent pathogenesis of syndrome, comprehend the link of inherent connection among some set formulae and know well the research achivement of traditional Chinese medicine and Western medicine so as to raise the level of using set formula. It is also important to fully utilize the feature of drugs with more effective, specially functional drug matches , regularity of dosage changing and technique of producing supplemental effects by properly combining drugs opposited to each other in property to increase effect of prescription. Combining skillfully more than one foumula may be an effecient way to forming prescription too.
摘要:Divide 40 Japanese large-earring white rabbits randomly into model group, large, medium, and small dosage of Shenxianshengmaiye (SXSM) group and Xinbao group. Create the model with sick sinus syndrome by external application of 20% methanal on the sino-atrial node. Observe the changes of heart rate and electro-physiological index of sinoatrial node. The results show that SXSM can markedly increase the sinus rhythm, shorten the sino-atrial conduction time (SACT) and sino-atrial reserve time (SART). And the effect of large dosage group was more obvious than Xinbao group.
摘要:After repeated cerebral ischemia and reperfusion, 50 minutes later, the mouse intracerebral glutamic acid (Glu) and asparaginic acid (Asp) level increased, then the level of gamma aminobutyric acid (GABA) increased as well. Both large and small dose of Kangdaiheji (KDHJ) can inhibit the increase of Glu and Asp. A large dose of KDHJ can lower the GABA near to normal level. In 50 minutes to 7 days after creating the mouse model of which the acetylcholinesterase (AchE) activity was inhibited, KDHJ improved the AchE activity.
摘要:Using histochemical staining and quantitative technology, observe rat glycogen in the skeletal muscles, changes of the enzyme related with energy metabolism and effects of TCM compound prescription Xiaopiyishen oral fluid (XPYS) in the rat model. Results show that: the contents of rat glycogen and succinic dehydrogenase (SDH) were not remarkably changed, while the level of myoglobulin adenosine triphosphatase (M ATPase) decreased and LDH increased markedly. After the administration of XPYS and panaxoside, the content of glycogen and SDH was remarkably increased, which improved the decrease of M ATPase and increase of LDH caused by establishing the rat model. Compared with the effect of XPYS, panaxoside was more effective on increasing the content of M ATPase.
摘要:Observe 58 patients’ nail fold microcirculation conditions. It was discovered that there existed apparent abnormal changes in the nail fold microcirculation, which was mainly expressed in the blood flow rate decreasing, apparent sympexis, etc. After taking TCM drugs with function of invigorating the spleen and replenishing qi , the deficiency of spleen-qi syndrome disappeared and the abnormal changes was corrected. This proved that the nail fold microcirculation can be taken as an objective index to assess the drugs’ effectiveness and the state of illness.
关键词:Deficiency of spleen qi;Nail fold microcirculation;Invigorating the spleen and replenishing qi;Clinical study
摘要:Use orthogonal design Lg (3 4) to screen out the best extraction condition. Assaytheabsorbanceof icariin which is an ingredient of lonspur epimedium, the principal drug in the granule. The transference rate of icariin was 71.2%. It proved the rationality of the optimum seeked extraction technology.
摘要:To assay the contents of coptisine respectively in Huanglian and the medicinal pair Huanglian with Ejiao through high efficiency capillary electrophoresis. Taking 15 25 minutes as reserving time, strychnine as internal labeling, and 0.05M sodium tetraborate (ph=7.0): methanol (85:15) as balanced solution. Results showed that the content of coptisine in the medicinal pair decreased.
摘要:mice models with vascular dementia (VD) were divided into 4 groups and administered respectively with 0.9% NS, TongMaiYiZhi capsule (TMYZ) and hydergine. Observe their behaviors in step-down avoidance test and water-maze test. Results: The mouse’s performance in the water labyrinth was obviously affected. The whole distance swimming time was prolonged and mistakes increased. TMYZ can improve the above indice and there was remarkable difference in statistics. It proved that TMYZ could strengthen the mouse in learning and memory.
关键词:TongMaiYiZhi capsule;vascular dementia;Cerebral ischemic reperfusion;learning and memory;mouse
摘要:To discuss the two types of TCM syndrome of liver’s dysfunction in promoting the free movement of qi , which are stagnation of liver qi and adverse flow of liver qi , on the intestinal absorption of experimental animal model. By the enzyme histochemical and electric microscopic technique, it was proved that the intestinal myoelectric activity, enzyme activity and ultrastructure of absorptive cell of the TCM syndrome were all lower than the normal group, and the group of liver qi stagnation was markedly lower than the liver qi adverse flow group.
摘要:Using Fura Ⅱ technique, examine the concentration of free calcium in rat celiac polymorphonuclear neutrophile granulocyte (PMN) under aseptic inflammation condition and the effect of bitter principles B of the Chinese lantern plant on it. Results: In resting state, the [Ca 2+ ] in PMN was 319.43+189.05nmol/L, the activation by zymosan could increase the [Ca 2+ ] remarkably, P<0.05. The Chinese medicine can inhibit the increase of [Ca 2+ ]. Differences between the groups were apparent, P<0.05. The feasibility of using Fura Ⅱ to examine [Ca 2+ ] in PMN was discussed as well and it proved that the Chinese Medicine could inhibit [Ca 2+ ].
摘要:Through clinical observation on using Yinao granules on 32 cases of vascular dementia, it showed that the main symptoms were improved markedly, treatment excellent effective rate was 20%, effective rate was 54% and total effective rate was 74%. The hemerheology was remarkably improved compared with pre treatment condition. There were not obvious changes in the routine analysis of blood, liver and renal function after the treatment. The clinical study initially proved the Yinao granules’ safety and reliable effect.
关键词:Yinao grnules;vascular dementia;clinical study
摘要:To make a new method of content assay of the berberine hydrochloride tablet, take spectrophotometric method and HPLC assay and compare with iodometric method at the same time. Results: The specificity of spectrophotometric mehtod and HPLC assay is stronger and can check out the forged product, so they are more accurate and reliable.
摘要:Dividing the experimental nephrolytic serum rat models into 3 groups: treatment group with cooling the blood and dissipating blood stasis method, group with kidney tonifying method and the blank control group, after filling for 8 weeks put them to death and then assay the hemorrheology indices of each group. The results show the hemorrheology indices of treatment group with cooling the blood and dissipating blood stasis method, which include whole blood viscosity, plasma comparing viscosity, hematocrit and fibrinogen content, are all markedly better than pathological group. The inter group comparison also differs greatly. But there is no obvious difference between the group with kidney tonifying method and the blank control group. It indicates that the TCM method of cooling the blood and dissipating blood stasis is more effective than the kidney tonifying method on improving the rat hemorrheology indices with experimental glomerulonephritis.
关键词:Cooling the blood and dissipating blood stasis;Kidney tonifying;Glomerulonephritis;hemorrheology;rat
摘要:A diabetes rat model was establisbed by intraperitoneal injection of streptozotocin. Observe the effects of Zhixiaotongmaining on the glomerular morphologic changes. The results show that: Compared to the normal control group, there are markedly increase of glomerular basement membrane width (GBMW), average mesentery area , average glomeruluar sectional area, , glomerular diameter and volume in the deabetes group, among which the model group is most remarkable, the western medicine group is second to it and the Chinese medicine group is the lest remarkable. So controlling nephrohypertrophy, modifying GBM widening and inhibiting mesentery proliferation are the main mechanism of action.
摘要:To study the anatrophic function of TCM compound prescription Wushenfang , a rat model under fatigue and stress condition was created by forced running and plantar electrostimulation. Treatment group was administered with Wushenfang decoction by stomach perfusion, the juvenile group, blank group with the same age and Vitamin E group as the control groups. Observe the erythrocyte deformability and the change of platelet aggregation rate. Results: in the model group, the erythrocyte deformability decreased and the platelet aggregation rate increased markedly, which was apparently distinct from the blank group, while in the Wushenfang group the changes above ameliorated. It suggested that Wushenfang can markedly improve the hemorrheological changes of presenium rat under fatigue and stress condition.
摘要:To observe the improvement by XiaoPiYiShen oral fluid (XPYS) on symptoms of 43 patients with chronic fatigue syndrome (CFS), take normal people as control group. Assess the patients and the normal people with measuring scales of fatigue, anxiety, depress and living event. Results:The patients compared with the normal people were in obvious depress and anxious state, the accumulative grades of the living event measuring scale was markedly higher as well. XPYS can improve the depressive and anxious state of CFS patients markedly, the total effective rate of clinical treatment reached 86.05%.
关键词:XiaoPiYiShen oral fluid;chronic fatigue syndrome;TCM Syndrome of stagnation of the liver-qi with deficiency of the spleen;clinical study