摘要:Western traditional medicine lays its foundation upon Four Element Humor Theory, while Chinese medicine takes Yin Yang Five Element theory as its basis. The holistic frames of the two medical systems coming from different cultures share many similarities and distinctions. The Comparative study was focused on these two theories, in order to make analysis of eastern and western sources of cosmology, natural philosophy, epistemology and methodology resulting in medicines, and to lead a new way to understand and carry out the radical task of integrating Chinese medicine to modern bio sciences.
摘要:Whether LiujingBianzheng (the differential diagnosis in accordance with the theory of six channels) fits for many a kind of febrile diseases due to external affection, or fits for exogenous febrile disease? Or, whether it fits for all diseases of internal medicine, not only those caused by exogenous pathogenic agents? These questions are correlated with how to look at the method of LiujingBianzheng and system of LiujingBianzhenglunzhi (determination of treatment based on the differential diagnosis in accordance with the theory of six channels) in the Treatise on Febrile Diseases . Through a discussion on the essence of this classic, it was thought in the Treatise on Febrile Diseases , the method and system of LiujingBianzheng fit for only exogenous febrile disease in a narrow sense.
摘要:Observe the effect of Yishenhuoxuexiezhuo and LPS on the expression of transforming growth factor β 1(TGF β 1) in rat mesangial cells. Methods: Rat mesangial cells were cultivated in vitro and divided into three groups, serum group with the decoction, LPS group and control group. The RT PCR technique was adopted to show the expression of TGF β 1 in these three groups. Results: LPS could markedly increase the expression of TGF β 1 compared with the control group, while the serum group could suppress this expression significantly. Conclusion: It revealed that Yishenhuoxuexiezhuo decoction could decrease the expression of TGF β 1 in rat mesangial cells.
摘要:Zhong Yan Ⅱ is an efficient antiviral complex TCM prescription, but the mechanisms of its action have not been identified. Such an understanding would be of vital importance and potentially useful for its application in clinical practice. Aim of this study was to assess the efficacy of Zhong Yan Ⅱ in antiviral activity against Simian Immunodeficiency Virus (SIV) and to examine its immunoregulatory effects on T cell function. The in vitro efficacy of antiviral activity was evaluated in a CEM SIVmac screening assay system. Ex vivo the cell cycle analysis and the IL 2 level by Con A-stimulated PBMCs from SIVmac251 infected monkey were performed. Results suggested that the antiviral efficacy in vivo of Zhong Yan Ⅱ was not directly suppressing viral replication and infection. Its efficacy in HIV infection and AIDS was contributed to its ability to regulate the immune function and induce faster reconstitution of the immune system.
摘要:S: Rat diabetes model (DM) was duplicated through streptozotocin(STZ) intraperitoneal injection. Not only effect of Zhixiaotongmaining on DM at earlier stage, effects of the content change of NO and endotheliolysin (ET) on the formation of hypernephrotrophy and high filtration were also studied. Results suggested that the increase of NO be an important factor to the high filtration, which could be inhibited by Zhixiaotongmaining through inhibiting the synthesizing of NO.
摘要:On the basis of CFS (chronic fatigue syndrome) rat model, discuss the index and ultrastructure of adrenal gland and the modulating function of Chinese medicine. Method: After establishing rat model, excise the adrenal gland to calculate the index and observe its ultrastructure of cortex under electron microscope. Results: Compared with normal rats, the index of adrenal gland in the group with Chinese medicine increased, but the rats with ginseng saponin decreased. Observe the ultrastructure of cortex under electron microscope, the structure of normal rats and the groups with Chinese medicine and ginseng saponin were almost the same. However, a bigger change of ultrastructure occurred to rats model. Conclusion: On basis of the CFS rat model, we observed the changes of ultrastructure of cortex under electron microscope and the injuries of function. It indicated one of the causes of fatigue could be the decreasing of irritability.
摘要:The effects of Siwu decoction on mouse model with radiation injury were investigated. The result indicated that ionized radiation could obviously suppress RBC immunoadhesive function and stem cell multiplication. After treatment with Siwu decoction, the RBC immunoadhesive function and the ability of stem cell multiplication in the irradiated mice were improved. This study provided scientific basis of using Siwu decoction for the treatment of radiogenic immunodeficiency.
关键词:Siwu decoction;Ionized radiation;Immune function of RBC;Stem cell;mouse
摘要:The inhibitory action of garlicin on structural remodeling of intra acinar pulmonary arteries (IAPA) under pulmonary hypertension (PHT) was studied. 42 rats were fed in hypoxic environment under normal atmospheric pressure (10%O 2 10 hours/day) and divided into control group, hypoxia group and hypoxia with garlicin group. On the 15th and 30th day of hypoxia, right ventricular systolic pressure (RVSP) was measured and pulmonary vessel changes were studied under light and electronic microscopes rspectively. Garlicin could decrease the pulmonary arteries pressure and prevent IAPA endothelial cells damage from hypoxia. Garlicin could also inhibit hypertrophic changes in tunica media, the proliferation of advantitial cellsofthe IAPA and muscularization of nonmuscular arteries. Therefore, preserving the IAPA wall cells and dilating IAPA by garlicin may play an important role in inhibiting structural remodeling of IAPA and pulmonary hypertension.
摘要:Ingredients in MiNing granules including Cangzhu (Rhizoma Atractylodis), Chuanhuangbai (Cortex Phellodendri Chinese), Dahuang (Radix et Rhizoma Rhei) and Guanmutong (Caulis Aristolochiae Manshuriensis) and the contents of Geniposide in three batches of samples were analyzed respectively through TLC and HPLC. The results showed that, the method was easy, sensitive and repetitive. The linear range of Geniposide was 1.012μg~3.036μg ( r =0.9992) and the average recovery was 102.25% (RSD=0.98%).
摘要:Study the relationship to the thickness of tongue fur and symptoms/syndromes in the acute infection of respiratory tract (AIRT). Methods: Patients were divided into three groups, mild thick fur, middle thick fur and severe thick fur according to the total score of the thickness of tongue fur. Quantitatively record the symptoms in interrogation and study the relationship between the thickness of the tongue fur and symptoms/syndromes. Results: In AIRT, when the fur was thin, the patient’s major syndromes were invasion of the lung by wind heat and wind heat exterior syndromes which belong to exterior syndromes. When the fur was thick ,the patient’s major syndromes were accumulation of phlegm heat in the lung and retention of pathogenic heat in the lung which belong to interior syndromes. The thickness of the fur increased with the seriousness of interrogated symptoms and the appearance rate of symptoms, which suggested excessive pathogenic heat , exhaustion of body fluid , reduced function of the spleen and stomach . Conclusion: In AIRT, if the thin fur becomes thicker, it suggests a severe internal invasion of the pathogenic factor, deep location of the disease and patients’ severe condition. It also suggests the three TCM pathogenesis which are excessive pathogenic heat, exhaustion of body fluid and reduced function of the spleen and stomach .
关键词:Thickness of the tongue fur;TCM mechanism;Quantitative;Acute infection of respiratory tract;syndrome;symptom
摘要:A course of treatment was taken on 30 patients. Observe clinical symptoms and physical signs, serological indexes, results of biochemical analysis and B type ultrasonic diagnosis pre and after treatment. Comparative study was carried on and the treatment was evaluated according to the criterion of therapeutic efficiency. Results: Clinical symptoms and physical signs were improved markedly, total symptoms accumulation had significant difference pre and after treatment, the overall effective rate of TCM symptoms and physical signs was 89 03%. The results of serological examination, liver function test and iconographic examination were all improved markedly. It’s proved that Tiaoganlipifang has remarkable efficacy on improving symptoms and physical signs of alcoholic hepatic fibrosis, improving liver function and reversing hepatic fibrosis.
关键词:Tiaoganlipifang;hepatic fibrosis;Alcoholic;clinical study
摘要:patients were taken into treatment group and 30 in control group. TCM treatment based on differential diagnosis by stages was taken mainly in the complex treatment. The control group was treated with 654 2. Observe the clinical effects and changes of the blood lipid. Result: In treatment group CHOL and TG were lower while HDL C and APO A were significantly higher ( P <0 01). In control group TG was lower while HDL C and APO A were higher ( P <0 05). The action in treatment group of lowering TG and raising APO A, was better than that of the control group ( P <0.05). The total effective rate of treatment group was 90.00% while that of the other was 76 67% ( P <0 05). The results showed that the complex treatment based on TCM differential diagnosis by stages was more effective than the treatment mainly with 654 2.
摘要:patients with acute upper respiratory infection were divided into treatment group with Chuanhuning and control group with erythromycin. Observe efficacy of the two groups. Results showed that, the total effective rate of treatment group was 93 33%, obviously better than the control group with the rate of 80 00%. After statistical treatment, there was a significant difference between groups ( P <0 05). It indicated that Chuanhuning has a better efficacy on acute upper respiratory infection.
关键词:Chuanhuning;Acute upper respiratory infection;Clearing away pathogenic heat and toxic materials