最新刊期
卷 0 ， 期 5 ， 2000
- 摘要：The Doctrine of the Life Gate formed in the Ming Dynasty is a great attempt of Chinese ancient medical doctors to explore the origin of life and the laws inside the life, and represents the early discoveries and understanding of the traditional Chinese medicine （TCM） about the endocrinological functions. The descriptions of anatomical site and functions of the life gate given by medical doctors in the Ming Dynasty, basically conform to the adrenal glands in the modern medicine. The authors of this paper have put forward a viewpoint of the life gate’s dynamic and static state. According to this viewpoint, the life gate is a life reproduction regulating center related to the integration of the five zang organs. When in a static state, the life gate is half closed in order to accumulate substance and energy for life reproduction; but when in a dynamic state, the life gate is fully open for the integration of the five zang organs so as to make their functions synchronous. This viewpoint holds that the eight extra meridians are the channels of the life gate, through which the five zang organs are integrated. The life gate, the origin of life and the resources of the ministerial fire, is characterized by its functions of yin yang mutual supplement. Different from those of the five zang organs and the twelve meridians, the functions of life gate represents the regularity of life activity and life regulating mechanism at the Taiji level. The results of the authors’ research have cleared up the long standing confusion between the kidney and the life gate in TCM. The authors believe that deepgoing studies on the doctrine of the life gate will promise optimistic prospects of the integration of the traditional Chinese and modern medicines at a higher level of life science.关键词：life gate;ministerial fire;Eight Extra Meridians;Different Academic Schools of TCM;Endocrinology;adrenal gland
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发布时间：2021-09-15 -
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- 摘要：The rat arteriovenous shunt thrombosis test showed that both Congsheng Capsules and Hydergine could obviously decrease both wet weight and dry weight of thrombus. The results may be related to the two drugs’ effects of inhibiting platelet aggregation and of reducing erythrocyte deformability and aggregation in the rat model of blood stagnation.
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发布时间：2021-09-15 - 摘要：The imitative vascular dementia rat model was established by repeatedly clipping the common carotid artery of the rat in combination with reducing the rat’s blood pressure to about 50 mm Hg with an abdominal injection of sodium nitroprusside. On the 7th day after cerebral ischemic reperfusion, rats in the model group showed obvious disturbance in study and memory; and their hippocampal CA1 region manifested obvious cell deletion while there was no significant change in the CA3 region. The authors consider this kind of model reliable and reproducible, and suitable for studying the mechanism of the injury caused by cerebral ischemic reperfusion, and for observing the relevant drug effects. In the same experiment, it was found that TCM preparation 9602 could significantly relieve the injury of the hippocamp and the disturbance in study and memory caused by cerebral ischemia.关键词：Cerebral Ischemic Model;Study and Memory;TCM Preparation 9602
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发布时间：2021-09-15 - 摘要：The mouse viral pneumonia model was created by the infection due to 24 LD 50 FM1 strain virus, and the model was treated with different drugs. On the fourth day after the mice were infected by the virus and treated with Xuanfeijiedu Granules （Granules for promoting pulmonary functions and removing toxic substance）, the animals’ trachea and lung were isolated and examined pathologically with naked eye, optical microscope, transmission electron microscope and scanning electron microscope. The results showed that the Xuanfeijiedu Granules could relieve the inflammatory lesion of the lung, and had an effect of protecting epithelial cells of tracheal mucosa.关键词：Xuanfeijiedu Granules;mouse;Respiratory Organs;Pathologic Change;FM1 Strain Virus
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发布时间：2021-09-15 - 摘要：Objective - to compare the regulating effects of TCM qi invigorating and qi regulating drugs on the energy charge of the skeletal muscle cells in rat’s thigh （SMCRT） both in vivo and in vitro, and to observe the effects of the polysaccharides extracted from qi invigorating drugs on the energy charge of SMCRT in vitro. Method - HPLC was used to determine the contents of ATP, ADP and AMP in SMCRT, and the value of the energy charge was calculated according to a routine formula. In the experiment, the qi invigorating drugs included ginseng, astragalus root, pilose asiabell root, and white atractylodes rhizome; and the qi regulating drugs were immature bitter orange, magnolia bark, green tangerine, and lindera root. Results - Both in vivo and in vitro tests showed that the qi invigorating drugs could increase the value of the energy charge while qi regulating drugs acted on the contrary. The polysaccharides showed no effect of increasing the value of the energy charge, but a tendency to decrease the value in a dose effect manner. Conclusion - qi invigorating and qi regulating drugs acted differently on the energy charge of SMCRT, and it could not be proved that the polysaccharides are the material basis of the qi invigorating drugs in their energy charge increasing action.关键词：Qi invigorating Drugs;Qi regulating Drugs;Energy Charge;skeletal muscle;Polysaccharide
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发布时间：2021-09-15 - 摘要：A TCM preparation named Fortified Xiaoshifanshi Powder was given to the mouse model of immune hepatic injury, and the results showed that the preparation could obviously decrease the serum ALT and AST activity in the animals of the model group in a certain dose effect manner, and inhibit the increase of IL 6 and TNF α levels with a positive correlation between the effect and the size of the dose.
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发布时间：2021-09-15 -
- 摘要：In this experiment the human cord blood hematopoietic cell （HCBHC） was used to cultivate a kind of cell whose phenotype is contrary to that of the cell with acute leukemia by a TCM drug culture method. First, HCBHC was cultivated with TCM drugs for clearing away heat and nourishing yin （CHNY）, and then, its cytoplasm was used to convert the phenotype of the cell with acute leukemia. The results showed that TCM drugs for CHNY, could decrease HCBHC multiplication rate, increase HCBHC differentiation rate, and cause the readjustment and recombination of HCBHC hematopoietic modulators; and the phenotype of HL60 cells could be converted by HCBHC cytoplasm cultivated with TCM drugs for CHNY, manifesting mature mononuclear macrophage differentiation, declined division rate, inhibition of multiplication, and apoptosis.关键词：HL60 Cell;differentiation;Traditional Chinese Drugs;Human Cord Blood Cytoplasm
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发布时间：2021-09-15 - 摘要：Rats were divided into control group, excess heat syndrome （EHS） group, and deficiency heat syndrome （DHS） group, and ultra violet spectrophotometer was used to determine the activity of succinate dehydrogenase （SDH） in the hepatic cell mitochondria in the rats of these groups. The results showed that SDH increased in both EHS group and DHS group, but it decreased in the two groups after traditional Chinese drugs （for clearing away heat and dispelling toxic substances, and for nourishing yin and clearing away heat） were given. The results imply that there is a positive correlation between these two syndromes （EHS and DHS） and the energy metabolism in the body; and the treatment with traditional Chinese drugs benefits the restoration of mitochondrial hyperactive respiration of hepatic cells to the normal level.关键词：Excess Heat Syndrome;deficiency heat syndrome;Mitochondrion;Succinate Dehydrogenase;liver
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发布时间：2021-09-15 - 摘要：TLC was used in this experiment to determine phytolaccatoxin in the decoction slices of Phytolacca acinosa processed by different traditional Chinese drug processing methods. The results showed that compared with the unprocessed Phytolacca acinosa, the phytolaccatoxin was reduced to 16.73% in the steamed slices, 21.88% in the vinegar boiled slices and 45.95% in the vinegar baked slices. The qualitative test found no histamin in Phytolacca acinosa.关键词：Phytolacca Acinosa;Traditional Chinese Drug Processing;Phytolaccatoxin
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发布时间：2021-09-15 -
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- 摘要：The primary hepatocarcinoma patients, on the first day when they received the Seldinger’s chemoembolization treatment for the first time, were divided into the western drug plus traditional Chinese drug （WDTCD） group and the western drug （WD） group. The traditional Chinese drug used in this study was a decoction prepared according to a modified formula named Tuolixiaodu Powder consisting of many traditional Chinese herbs （Codonopsis pilosula, Astragalus membranaceus or Astragalus membranaceus mongholicus, Poria cocos, Atractylodes macrocephala, Liquorice, Paeonia lactiflora, Angelica sinensis, Ligusticum chuanxiong, Platycodon grandiflorum, Angelica dahurica, Honeysuckle flower, Gleditsia sinensis, Hedyotis diffusa, etc.）. The patients’ symptoms of the fever, nausea, vomit, abdominal pain, hepatalgia and the patients’ damage of hepatic functions all caused by the chemoembolization were treated with WDTCD and WD, respectively. The results showed that the lasting time of fever and other symptoms in WDTCD group was shorter than that in WD group （ P <0 01）, and the values of the 4 routine indexes of hepatic functions （total bilirubin, direct bilirubin, indirect bilirubin and alkaline phosphatase in serum） in WDTCD group were all lower than those in WD group （ P <0 01）, which implies that Tuolixiaodu Powder has antagonistic effects on the large area histological necrosis caused by the chemoembolization, and on the deficiency of vital qi caused by both the chemoembolization and some other drugs used in routine treatment of the hepatocarcinoma patients.关键词：hepatocarcinoma;Chemoembolization;Tuolixiaodu Powder;Maintenance of Vital qi;Expelling of Toxic Substance
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发布时间：2021-09-15 - 摘要：The double antibody sandwich ELISA was used in the determination of the levels of plasmatic IL 10, IL 6 and TNFα in 57 cases of chronic renal insufficiency （CRI） and 20 healthy human subjects. CRI patients were divided into different TCM syndrome pattern groups and the healthy human subjects were taken as normal control. The results showed that the levels of IL 6 and TNFα of all different TCM syndrome patterns of CRI were higher than those of the normal control, and there was a significant difference between the both yinandyang deficiency group and the normal control （ P <0.05）; and the results also showed that the level of IL 10 of all different TCM syndrome pattern groups were higher than that the normal control, and there was a significant difference between the splenonephric qi deficiency group and the normal control （ P <0.05）, and a markedly significant difference between the bothyinandyang deficiency group and the normal control （ P <0.01）. From the results, it can be concluded that all the different TCM syndrome patterns of CRI are related to different degrees of the disorder of cell immune functions, and IL 10, IL 6 and TNFα can be used as the criteria in diagnosing CRI patients by TCM differential diagnostic method.关键词：Chronic Renal Insufficiency;TCM Differential Diagnostic Syndrome Pattern;cytokine;Immunology
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发布时间：2021-09-15 - 摘要：This clinical experiment found that the Xiezhuonaqi Decoction, which consists of Acorus gramineus, Cornus officinalis and Lepidium apetalum or Descurainia Sophia, could increase the level of 2,3 diphosphoglyceric acid in RBC and accordingly, significantly improve the pathological state of the patients of chronic type Ⅱ respiratory failure, for example, the obvious relief of hypoxia and carbon dioxide retention.关键词：Chronic Type II Respiratory Failure;Xiezhuonaqi Decoction;2,3 Diphosphoglyceric Acid
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发布时间：2021-09-15 -
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