最新刊期
卷 0 ， 期 0 ， 2020
-
-
-
-
-
-
- 摘要：The effects of Jianpiyiqizhixue Formula （JF） on the levels of estradiol （E 2） and progesterone （P） in the serum and on the estradiol receptor （ER） and progesterone receptor （PR） in the hypothalamus and uterus were investigated in the rat model of deficiency of splenic qi. The model was established by inducement of swimming and gastric perfusion of senna water extract. The levels E 2 and P were detected by radioimmunoassay and the levels of ER and PR were measured by the immunohistochemical method and image analysis, in order to observe the effects of JF on the rat model of deficiency of splenic qi. The results showed that JF could restore the normal levels of E 2 and P, increase the level of ER in the hypothalamus and uterus, and decrease the level of PR in the hypothalamus in the rats of deficiency of splenic qi, which suggests that JF can improve the reproductive function of the rats of deficiency of splenic qi.关键词：Deficiency of Splenic Qi;Jianpiyiqizhixue Formula;estrogen receptor;Progestogen Receptor
- 12
- |
- 185
- |
- 2
发布时间：2021-09-15 - 摘要：The effects of Xianzhen Tablets （XT） on the expression of RAGE mRNA in the aorta were observed in the diabetic rats. The diabetic rat model was induced by a single injection of streptozotocin into the left lower part of the abdominal cavity of the animal. The diabetic model rats were randomly divided into the model group, XT treating group, and aminoguanidine treating group, and there were 10 rats in each group. A normal control group consisting of 10 rats was also set up. The in situ hybridization method was adopted for the experiment. The results showed that the gray scale value of the expression of RAGE mRNA was markedly increased in endothelial cells of the aorta, manifesting over expression, in the model group; the gray scale value of the expression of RAGE mRNA decreased in endothelial cells of the aorta in the XT treating group, which was similar to that in the aminoguanidine treating group （ P >0 05）, and very different from that in the model group （ P <0 05）. The results suggest that as same as aminoguanidine, XT can decrease the over expression of RAGE mRNA, exerting a marked regulative effects on the increased expression of RAGE mRNA in the aortic vessel, which implies that XT has protective effects against the damage to the aortic vessel by hyperglycemia.
- 8
- |
- 81
- |
- 4
发布时间：2021-09-15 - 摘要：In order to set up the technology for adsorbing and separating total flavone from Puhuang （Pollen of Typha angustifolia or Typha orientalis） with macroporous adsorption resin, 13 types of macroporous adsorption resin were investigated. The total flavone adsorption capacity, total flavone content and total flavone recovery rate were used as the evaluating criteria. The UV-VIS spectrophotometric method was used in the determination of total flavone content, and TLCS was used in the evaluation of the leaking curve. The results showed that among 13 types of macroporous adsorption resin, the AB-8 was the best for adsorbing and separating Puhuang total flavone in the following technological conditions: the concentration of the sample of Puhuang extract was 20 mg/ml; the maximum adsorbing capacity for Puhuang total flavone, 9.36 mg/ml; the current velocity of adsorption, 2 ml/minute; the eluting reagent, 50% ethanol （7 times the volume of the resin）; eluting velocity, 2 ml/minute; and the AB-8 resin could be used 3 times repeatedly. The results also showed that AB-8 macroporous adsorption resin could well adsorb and separate Puhuang total flavone under the set technological conditions, and the content of Puhuang total flavone in the ethanol eluant was over 45%, with a total flavone recovery rate of over 85%.关键词：Pollen of Typha angustifolia or Typha orientalis;Total Flavone;Macroporous Adsorption Resin
- 12
- |
- 893
- |
- 9
发布时间：2021-09-15 - 摘要：The ffects of Gualouxiebai Decoction （GD） on the Levels of laminin （LN） and procollagen Ⅲ （PC Ⅲ） in the bronchio alveolar lavage fluid （BALF） were observed in the rat with pulmonary fibrosis. The rat model of pulmonary fibrosis was induced by pingyangmycin （bleomycin）. The model rats were divided into the model group and drug treating group. The rats in the drug treating group were given GD by gastric perfusion for 28 days, and then executed for the histopathological observation. The results showed that the severity of alveolitis and pulmonary fibrosis was greater, and the levels of LN and PC Ⅲ in BALF were markedly higher in the model group than those in the rats in the drug treating group and normal control group （ P <0 05）, which suggests that GD can obviously relieve the severity of alveolitis and pulmonary fibrosis, and inhibit the increase in the levels of LN and PC Ⅲ in BALF.关键词：Gualouxiebai Decoction;pulmonary fibrosis;Bronchio alveolar Lavage Fluid;laminin;Procollagen Ⅲ
- 7
- |
- 198
- |
- 4
发布时间：2021-09-15 - 摘要：In order to investigate the mechanism of Yushu Buccal Tablets （YBT） in treating acute pharyngitis, effects of YBT on the serum interleukin-6 （IL-6） and tumor necrosis factor （TNF） were observed in the rats with acute pharyngitis. 50 Wistar rats were divided into 5 groups, namely the normal control group, large dose YBT group, small dose YBT group, model control group, Caoshanhu group, and each group consisted of 10 animals. The rat model of acute pharyngitis was induced by spraying the larynx with strong ammonia water. Distilled water, large dose of YBT solution （1.6 g/kg）, small dose of YBT solution （0.4 g/kg） and Caoshanhu Buccal Tablets solution （4.8 g/kg） were respectively given to the animals in each corresponding group. On the 7th day of the experiment, the levels of serum IL-6 and TNF were detected in the blood of the femoral vein of the animals in the 5 groups respectively, and at the same time, the pharyngeal mucosal and submucosal tissues of the animals were also examined pathomorphologically and ultrastructurally. The results showed that both large dose and small dose of YBT could effectively decrease the percentage of blood lymph cells and the levels of serum IL-6 and TNF, and improve the pathologic picture and ultrastructure of the pharyngeal tissues in the model animals.关键词：Yushu Buccal Tablets;Acute Pharyngitis;interleukin-6;tumor necrosis factor
- 7
- |
- 223
- |
- 8
发布时间：2021-09-15 -
- 摘要：The effects of Kangdai No.1 on the dynamic changes in bcl 2 and bax expressions in hippocampal astrocytes in the mice with the cerebral injury caused by transient forebrain ischemia and reperfusion, and the relationship between the effects of Kandai No.1 and ischemic neurons were investigated by the immunohistochemical method. The results showed that bcl 2 expression was positive in 3 to 7 days after ischemia and reperfusion and bax expression was positive in 7 to 10 days after ischemia and reperfusion in the animals in the model group; both bcl 2 and bax expressions were weakened in the animals in the Kangdai No.1 treated group compared to those in the model group; there were no bcl 2 and bax expressions in the normal control group and sham operation group; and the intensity of bcl 2 and bax expressions in the astrocytes was related with the survival state of neurons. The results indicated that there were dynamic changes in bcl 2 and bax expressions in hippocampal reactive astrocytes after forebrain ischemia and reperfusion, and Kangdai No.1 had good protective effects against the injury of astrocytes and neurons caused by forebrain ischemia and reperfusion.
- 8
- |
- 115
- |
- 4
发布时间：2021-09-15 - 摘要：The content of 2α, 3β, 19α, 23 tetrahydroxy ursolu 12 ene 28 carboxylic acid was quantitatively determined by HPLC in Jinyingzi （dried hip of Rosa laevigatae） of different places of production. The conditions for the experiment were as the following: Kromasil C 18 （4.6 mm×250 mm, 5 μm） column; detection wavelength, 203 nm; column temperature, 35℃; and the mobile phase, CH 3CN H 2O （35:65） with a flow rate of 1.0 ml/min. The results showed that 2α, 3β, 19α, 23 tetrahydroxy ursolu 12 ene 28 carboxylic acid was well separated from other components, the linear range of the calibration curve was between 0 4 μg～10 μg, the sample recovery was 102 5%, and the relative standard deviation was 2 66%. The results suggested that there were great differences in the content of 2α, 3β, 19α, 23 tetrahydroxy ursolu 12 ene 28 carboxylic acid among Jinyingzi from different places of production. It can be concluded that the method used in this experiment is simple and accurate and can be used to determine the content of the component in other crude drugs and preparations.关键词：Tetrahydroxy Ursolu 12 Ene 28 Carboxylic Acid;HPLC;Quantitative Determination;Hip of Rosa laevigatae
- 8
- |
- 364
- |
- 1
发布时间：2021-09-15 - 摘要：The wholel methanol extract of Guanzhong （the rhizome of Dryopteris crassirhizoma） and its 4 parts of different chemical polarity were tested by Peters 4-day inhibition method for screening their antimalarial activity. The results showed that part A and part B of the extract possessed relatively strong antimalarial activity.关键词：Guanzhong;Rhizome of Dryopteris crassirhizoma;Antimalarial Activity;screening
- 8
- |
- 298
- |
- 7
发布时间：2021-09-15 -
-
- 摘要：A randomized, controlled clinical trial of the treatment for cognitive impairment due to multi infarct dementia was carried out. 40 Mild and moderate cases of multi infarct dementia were randomly divided into the treating group and control group. The treating group was given Bonande Tablets, a TCM compound preparation, 1 tablet （about equal to 15 g of raw herbs） each time, 3 times daily. The control group was given duxil, 1 tablet （40 mg） each time, 2 times daily. The administration of both groups lasted for 6 weeks. The cognitive function was assessed by Bristol New Battery of Neuropsychological Tests （BNBNT, a Chinese version）, respectively at the baseline and the end point. The results showed that Bonande could significantly improve the total MMSE score, attention/calculation, delayed recall, language items and total WMS R score; markedly improve the MMSE subscale orientation, and the WAIS R subscale free recall, reading and classification of colors and shapes （included in language and central executive function）; and have remarkable improving effects on the total scores related with language items and central executive function. The results also showed that the total effective rate of Bonande was higher than that of duxil for improving total intelligence, language items and central function, speeding, and visual spatial ability. The results suggest that Bonande Tablets possess marked effects for relieving cognitive impairment due to mild and moderate multi infarct dementia and are worth further clinical studies.关键词：Cognitive Impairment;Multi infarct Dementia;TCM Therapy;Clinical Trial;Jiannaoan Tablets
- 8
- |
- 129
- |
- 17
发布时间：2021-09-15 - 摘要：With Kangbingdu Oral Solution （KOS） as a control, the therapeutic effects of Qingfei Decoction （QD） on virus infection of respiratory tract （VIRT） were investigated. 60 VIRT patients were randomly divided into QD-group （36 cases） and KOS-group （24 cases）. The changes in the severity of the symptoms and signs, the activity of serum natural killers （NK）, and the levels of serum interferon （IFN-γ） and interleukin-2 （IL-2） were observed before and after the treatment with the two preparations respectively in the patients in the two groups. The results showed that the effective rate of QD for treating the symptoms and signs of VIRT was much higher than that of KOS, and QD could markedly increase the activity of NK and the levels of IFN-γand IL-2, which suggests that QD is better than KOS for treating VIRT.
- 8
- |
- 148
- |
- 2
发布时间：2021-09-15 - 摘要：The clinical efficacy of Tangluoning for treating diabetic peripheral neuropathy （DPN） and the mechanism of the efficacy were investigated. 48 DPN patients conforming to the diagnostic criteria were randomly divided into the treating group and control group. On the basis of basic treatment, the former was given Tangluoning （for benefiting qi and nourishing yin, tonifying the liver and kidney, and activating blood circulation）, and the latter was given methycobal （mecobalamin）. The changes in the symptoms, nerve conduction velocity （NCV）, microcirculation in the limbs and the content of sorbitol in the red blood cells （RBC） were observed in the patients. The results showed that the total effective rate of the treating group was 91 67% and that of the control group, 62 50%, and there was a significant difference between the two rates （ P <0 01）. The results also showed that Tangluoning could markedly relieve the symptoms such as numbness of the limbs, pain, spasm, weakened ankle reflex, improve the nerve conductive velocity and microcirculation of the limbs and decrease the content of sorbitol in RBC, with no obvious side effects found during the treatment.关键词：Tangluoning;Diabetic Peripheral Neuropathy;Nerve Conductive Velocity;microcirculation;Sorbitol
- 7
- |
- 202
- |
- 10
发布时间：2021-09-15 - 摘要：The clinical efficacy of Kangaixiaoshui Cream （KC） for treating malignant hydrothorax was investigated. KC, a TCM preparation for external application was applied externally on the chest wall of the patients with malignant hydrothorax, and the patients in the control group were treated by the intrapleural immunotherapy （IIT）. 50 Neoplastic patients with malignant hydrothorax （PS >2） were divided into KC group and IIT group, and comparison was made between the 2 groups concerning the pleural effusion, chest pain, quality of life and the weak positive expression rates of PCNA. The results showed that the effective rate of KC for treating malignant hydrothorax was 56%, higher than that of IIT （48%）; and KC could markedly relieve chest pain and improve the quality of life, and inhibit the proliferation of tumor cells in hydrothorax.关键词：Kanaixiaoshui Cream;Malignant Hydrothorax;TCM Preparation;External Application
- 9
- |
- 352
- |
- 4
发布时间：2021-09-15 -
-
-
-
-
-
-
-
- Postal code：100029
- Tel：(010)53911857 Email：jbutcm@bucm.edu.cn
- Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19
京公网安备11010802024621 - It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
- Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.
0