最新刊期
卷 0 ， 期 2 ， 2003
- 摘要：Although the syndrome differentiation and the treatment according to the differentiated syndromes are the essence of the clinical traditional Chinese medicine （TCM）, both the terms for differentiated syndromes and the classification of the differentiated syndromes need to be standardized urgently. In China, the research of TCM syndrome differentiation started in 1950s and in 1980s, the research on the standardization of TCM syndromes was launched. But up to now, yet the classification, nomenclature and diagnostics of TCM syndromes have not been unified, the reason of which is that the diagnostic system of TCM syndromes is a complicated nonlinear macrosystem. According to the results of their literature research and the experience of the Research Group of the Diagnostic Standardization of TCM Syndromes of Apoplexy, the authors of this paper have raised the following hypothesis: by a decomposition and analysis method, 29 syndrome factors can be extracted from the six major categories of TCM syndromes, namely, the syndromes due to the six exopathogens, syndromes due to the five endogenous pathogens, syndromes related to qi, syndromes related to the blood, syndromes related to yin and yang, and the syndromes related to other pathogens. Then, these 29 syndrome factors can be handed to TCM practitioners after they are standardized, and the TCM practitioners can make flexible cross-combinations of these syndrome factors when they make syndrome differentiation in their clinical practice. The authors of this paper hope that they can provide a new approach for the research of TCM syndromes.关键词：Standardization of TCM Syndromes;Nomenclature;classification;Syndrome Factor
- 14
- |
- 1793
- |
- 77
发布时间：2021-09-15 -
-
-
- 摘要：Objective To establish the rat model of liver depression syndrome. Methods: A method of random combinations of various kinds of unpredictable chronic stress was adopted in the establishment of the model of liver depression syndrome in rats; during the experiment, the body weight of the rats and the consumption of 1% sugar water by the rats were observed, and the level of ACTH in the plasma of the rats was detected by radioimmunoassay. Results The consumption of 1% sugar water markedly lowered at the ends of the 2nd and the 3rd weeks of the experiment, respectively, in the rats in the model group, as compared with that before the experiment （ P<0 05, P<0 01 ）; the consumption did not show notable change during all the 3 weeks of experiment in the amitriptyline group; the consumption increased at the ends of the 2nd and the 3rd weeks in the Xiaoyao Powder group, as compared with that before the experiment （ P <0 05）; the consumption was significantly less at the ends of the 2nd and the 3rd weeks in the model group than that in the control group （ P<0 01, P<0 05 ）; the consumption was significantly bigger at the ends of the 2nd and the 3rd weeks in the Xiaoyao Powder group than that in the control group （ P<0 05, P<0 01 ）; and there was no significant difference between the consumption in the amitriptyline group and that in the control group. As compared with the body weight of the rats in the control group, that of the rats in the model group, amitriptyline group and Xiaoyao Powder group all markedly lowered at the ends of the 1st, 2nd, and 3rd weeks （P<0 05, P<0 001 ） while the body weight of the rats in the amitriptyline group and Xiaoyao Powder group was markedly higher at the ends of the 2nd and the 3rd weeks than that of the rats in the model group （ P<0 05, P<0 01 ）. The level of ACTH increased in the plasma of the rats in the model group （ P <0 01） while the increased level of ACTH decreased to a certain degree in the amitriptyline group and Xiaoyao Powder group （ P<0 01, P<0 05 ）. Conclusion The rat model of liver depression syndrome has been initially established by the method of random combinations of various kinds of unpredictable chronic stress and by the observation of the consumption of 1% sugar water, which may comparatively well simulate the core symptoms of TCM liver depression syndrome.关键词：Liver Depression Syndrome;chronic stress;Consumption of 1% Sugar Water;Xiaoyao Powder;rat
- 8
- |
- 851
- |
- 29
发布时间：2021-09-15 - 摘要：Objective To investigate the expression of a proapoptotic gene, cysteinyl aspartate specific proteinase 3 （caspase 3）, in the forebrain and the effects of the total saponin from sanqi （the dried root of Panax notoginseng） on the expression of caspase 3 in the rats with intracerebral hemorrhage. Methods In situ hybridization was used to observe the changes in the expression of caspase 3 mRNA in the forebrain in the rats with intracerebral hemorrhage induced by collagenase in the total saponin group and the control group; immunohistochemical staining was used to observe the changes in the expression of caspase 3 p20. Results The expressions of caspase 3 mRNA and caspase 3 p20 mainly appeared in the area of the focus and around the focus, the cortical Ⅱ～Ⅴ layers and the hippocampal CA 2 - CA 3 subregions; and the positive cells appeared to be denatured neurons and gliocytes. In the animals in the total saponin group, there was a marked decrease in the number of the positive cells, the staining of which was pale in color. Conclusion The total saponin from sanqi can reduce apoptosis, and support the survival of the neurons and promote their repairing of damage in the forebrain in the rats with intracerebral hemorrhage, through inhibiting the transcription of caspase 3 mRNA and the activation of caspase 3.关键词：Cysteinyl Aspartate Specific Proteinase 3;Total Saponin from Sanqi （Panax notoginseng）;intracerebral hemorrhage;apoptosis;In Situ Hybridization;immunohistochemistry;rat
- 9
- |
- 252
- |
- 4
发布时间：2021-09-15 - 摘要：Objective To observe the effects of Wenpi Decoction （WD） on the levels of serum creatinine, BUN, and 24 hour urine protein in the rats with 5/6 nephrectomy. Methods The rat model of renal fibrosis was established by 5/6 nephrectomy; PAM HE staining was used to observe histomorphological changes in the model rats; and imaging analysis techniques were used to analyze the pathologic staining results. Results WD could markedly decrease the levels of the serum creatinine （ P <0 05）, BUN （ P <0 01） and 24 hour urine protein （ P <0 01）. Conclusion WD can lower the ratio of kidney weight to body weight, inhibit compensatory hypertrophy of the residual kidney, and reduce the degree of glomerulosclerosis and renal interstitial fibrosis, by which the renal functions are protected.关键词：Wenpi Decoction;renal fibrosis;Serum Creatinine;BUN;rat
- 8
- |
- 153
- |
- 1
发布时间：2021-09-15 - 摘要：Objective To study the protective effects of Naoshuankang （NSK） against the cerebral functional decline induced with D galactose in mice. Methods The model of cerebral functional decline was induced by subcutaneously injecting D galactose in the nape of the mice. The protective effects of NSK against the cerebral functional decline were observed by detecting the changes in learning and memorizing abilities, SOD and GSH Px activities, and the levels of MDA and lipofuscin in the model mice. Results: All three NSK doses of 100 mg/kg, 50 mg/kg and 25mg/kg could improve learning and memorizing abilities to different degrees, markedly enhance cerebral SOD and GSH Px activities, and decrease the levels of MDA and lipofuscin （ P<0 05, P <0 01）. Conclusion Inhibiting cerebral lipid peroxidation and increasing the ability of cerebral antioxidation may be one of the mechanisms of the effects of NSK in improving abnormal behavior of the patients and reliving senior dementia.关键词：Naoshuankang;D galactose;lipid peroxidation;mouse
- 6
- |
- 76
- |
- 2
发布时间：2021-09-15 - 摘要：Objective To observe the curative effects of Compound Shenhua Capsules （CSC） on modified chronic nephritis due to serum sickness in rats. Methods The rat model of modified chronic nephritis due to serum sickness was established by the traditional method and other techniques such as one side nephrectomy, feeding bovine serum albumin acidated water every other day, intraperitoneal injection of lipopolysaccharides, etc.; the drug fosinopril was used as a control; and the effects of CSC on some biochemical, immunological and pathological criteria were observed in the model rats. Results CSC could significantly lower the weight of the kidney and the index of kidney weight, decrease the level of urinary protein, increase the level of serum protein, reduce the levels of cholesterol and triglyceride, improve renal function, correct the dysfunction of blood coagulation, relieve the renal pathologic and immunofluorescent changes, and decrease the level of the expression of the proliferating cell nuclear antigen. Conclusion CSC has rather good curative effects on chronic nephritis due to serum sickness in rats.关键词：Compound Shenhua Capsules;Chronic Nephritis Due to Serum Sickness;proteinuria;renal function;Pathologic Change;proliferating cell nuclear antigen;rat
- 9
- |
- 116
- |
- 2
发布时间：2021-09-15 - 摘要：Objective To study the effects of berberine, oleanolic acid and allitridi to see whether they can exert, either by directly acting on hepatocytes or by activating the secretion of insulin, the effect of lowering the level of glucose. Methods HepG2 cells, the phenotype of which is similar to that of the human hepatocytes, were used to detect the 24 hour consumption of glucose in the culture fluid; βTC3 cells, which can stably secrete insulin, were used to detect the release of insulin; and MTT assay was used to monitor the proliferation of the cells. Results Berberine could increase the glucose consumption of HepG2 cells by 69 1% （ P <0 0001）, and both oleanolic acid and allitridi could slightly elevate the glucose consumption; oleanolic acid could decrease the insulin release of βTC3 cells by 25%～29% （ P <0 01） while both berberine and allitridi did not show marked effects on the insulin release. Conclusion Berberine can exert a remarkable effect for lowering the level of glucose by acting on hepatocytes.关键词：berberine;oleanolic acid;Allitridi;HepG2 cell;βTC3 cell;Glucose Metabolism
- 8
- |
- 454
- |
- 3
发布时间：2021-09-15 - 摘要：Objective To screen the Chinese herbal drugs that possess marked effects in the preservation of the isolated heart from large amounts of Chinese herbal drugs that have certain myocardium protective effects. Methods The isolated heart model induced by Langendorff’s perfusion was adopted, and Chinese herbal drug injections were added into the modified Euro Collins heart preserving solution （mEC solution） with the pure mEC solution as a control. The cardiac functions of the isolated heart preserved for 3 hours and the revivification rate of the isolated heart preserved for 7 5 hours and 9 hours, respectively were observed. Results As compared with the results from the control group, Jisheng injection, Ciwujia injection and Honghua injection could improve the cardiac functions of mouse isolated heart preserved for 3 hours, and increase the revivification rate of the isolated heart preserved for 7 5 hours. The order of the Chinese herbal injections used in the experiment according to their potency of revivifying the preserved isolated heart was: Honghua injection > Jisheng injection > （Ciwujia injection, Huangqi injection and Ligustrazine injection） > Danggui injection; and Honghua injection and Jisheng injection showed the shortest heart beating restoring time. Conclusion The effects of Honghua injection on prolonging the preservation time of the isolated heart were more marked than those of Jisheng injection.关键词：Chinese Herbal Drug;Langendorff’s Perfusion;Heart preservation;Heart Preserving Solution
- 9
- |
- 104
- |
- 8
发布时间：2021-09-15 -
Effects of Bushentongluo Formula on the Gene expression of NOS in the Penis Tissue of Castrated Rats
摘要：Objective To find the relationship between the gene expression of NOS and the effects of Bushentongluo Formula （BF） on the erection of penis. Methods 40 Adult rats were randomly divided into the control, castrated, BF, and testosterone propionate （TP） groups, and the testes of the rats in the last three groups were removed. BF group was given BF and TP group was given TP. Three weeks after the orchiectomy, the penis tissues of the rats in BF group and TP group were taken for detecting the expression of NOS mRNA by using PCR. Results The expression of NOS mRNA in the rats in the castrated group was lower than that in the other three groups. The order of the groups in which the expression of NOS mRNA showed an increase was: the control group > TP group > BR group. The internally controlled amounts of NOS mRNA in the control group, TP group and BF group were larger than those in the castrated group （ P <0 05）, but there was no marked difference between the internally controlled amounts of NOS mRNA in TP group and BF group （ P >0 05）. Conclusion BF can exert an important role in the erection of penis through regulating the expression of NOS mRNA.关键词：NOS;erectile dysfunction;Bushentongluo Formula;rat- 8
- |
- 53
- |
- 1
发布时间：2021-09-15 - 摘要：Objective To analyze the fatty acids in tiannanxing （the Rhizome of Arisaema erubescens）. Method GC MS techniques were used to analyze the compounds of methyl ester type in the petroleum ether extract of tiannanxing. Result 100 chromatographic peaks were obtained by separation on the DB5MS glass capillary column, the length of which was 30 m and the diameter of which was 0 25 mm, with He as the carrier gas, at a program controlled temperature. Conclusion Among the 100 chromatographic peaks, 41 components were identified through searching the NIST database.关键词：Rhizome of Arisaema erubescens;GC MS;Fatty Acid
- 9
- |
- 376
- |
- 3
发布时间：2021-09-15 - 摘要：Objective To establish a method used for quantitatively determining paeoniflorin in the effective fraction of Shenshaoxinxin Formula. Method HPLC techniques were adopted: the YWGC 18 column （250 mm×4 6 mm, 10 μm） was used, the mobile phase was acetonitrile-0 2% phosphoric acid （14∶86） at a flow rate of 1 ml/minute, and the detecting wavelength was 230 nm. Results The average recovery was 96 9% and RSD was 2 39% （ n =5）. Conclusion This method is simple and accurate, and can be used as one of the methods for controlling the quality of the effective fraction of Shenshaoxinxin Formula.关键词：paeoniflorin;Shenshaoxinxin Formula;HPLC;quantitative determination
- 13
- |
- 71
- |
- 6
发布时间：2021-09-15 - 摘要：Objective To establish a method used for quantitatively determining chlorogenic acid in Jianpijiangzhi Granules. Method HPLC techniques were adopted: the YWGC 18 column （250 mm×4 6 mm, 10 μm） was used, the experiment was carried out at room temperature, the mobile phase was 10% acetonitrile glacial acetic acid （5∶0 1） at a flow rate of 1 ml/minute, and the detecting wavelength was 329 nm. Results The linear range of chlorogenic acid was between 0 0208 μg～0 104 μg （ r=0.9994, n=5 ）, the average sample recovery was 96 23%; and RSD was 0 798%. Conclusion This method is accurate and practical, and can be used for controlling the quality of Jianpijiangzhi Granules.关键词：Jianpijiangzhi Granules;chlorogenic acid;HPLC
- 9
- |
- 97
- |
- 1
发布时间：2021-09-15 - 摘要：Objective To investigate the mechanism of the effects of Tiaobufeishen Capsules （TC） in the treatment of chronic obstructive pulmonary disease （COPD） at stable stage. Method 60 Patients of COPD at stable stage manifesting TCM syndrome of deficiency of both the lung and kidney were randomly divided into the treating group （30 cases） and control group （30 cases）; the former was given TC and the latter, Gubenkechuan Tablets. Results TC overall effective rate in treating COPD at stable stage and TC effective rate in treating the TCM syndrome alone were 93 33% and 96 67%, respectively; and there was a significant difference between the effective rates in both groups. TC effects for relieving dyspnea and improving pulmonary functions and the blood gas analysis criteria were better in the treating group than those in the control group. Conclusion TC possesses rather good effects for treating COPD at stable stage manifesting TCM syndrome of deficiency of both the lung and kidney.关键词：Tiaobufeishen Capsules;Chronic Obstructive Pulmonary Disease at Stable Stage;Syndrome of Deficiency of Both the Lung and Kidney;clinical trial
- 11
- |
- 628
- |
- 4
发布时间：2021-09-15 - 摘要：Objective To investigate the correlation between TCM syndrome patterns of gastric carcinoma and the expressions of the genetic proteins p53, bcl 2 and bax, for revealing the inner relationship between a disease and a TCM syndrome and finding the material basis of a TCM syndrome. Methods 65 Cases of poorly differentiated gastric carcinoma at the progressive stage were chosen and divided into the group of splenic deficiency （SD） and the group of non splenic deficiency （NSD） on the basis of TCM syndrome differentiation, and their main symptoms were processed by a semi quantitative scoring method; the normal control group was made up by 20 subjects. The expressions of the genetic proteins p53, bcl 2 and bax in the pathologic tissues were detected by the S P method. Results The rates and the levels of the positive expressions of p53 and bcl 2 were significantly higher in the patients in SD group than those in NSD group （ P <0 05）; the level of the positive expression of bax was lower in SD group than that in NSD group but there was no significant difference between the two results; there was a positive correlation between the values of the symptomatic scoring and the levels of the expressions of p53 and bcl 2 in SD patients （ P <0 01）, but there was no such correlation between the values of the symptomatic scoring and the level of bax expression; and there was also no correlation between the values of the symptomatic scoring and the levels of the expressions of p53, bcl 2 and bax in NSD patients. Conclusion The discrepant expressions of p53 and bcl 2 found in this experiment are related to the pathogenesis of SD syndrome of gastric carcinoma, and p53 and bcl 2 genes are part of the material basis of SD syndrome.关键词：gastric carcinoma;TCM Syndrome Pattern;Syndrome of Splenic Deficiency;p53;bcl 2;bax
- 8
- |
- 381
- |
- 2
发布时间：2021-09-15 - 摘要：Objective To investigate the preventive effects of Chang’antai on postoperative metastasis of carcinoma of large intestine and the effects of the same medicine on the level of CEA in the serum and WBC count of the peripheral blood. Method 80 Cases of postoperative metastasis of carcinoma of large intestine were randomly divided into the Chang’antai group, chemotherapy group and Chang’antai plus chemotherapy group. Results There was no significant difference between the rates of postoperative metastasis in all the three groups; the postoperative level of CEA in the serum decreased earlier in the Chang’antai group than in other groups （ P <0 05）; WBC count markedly decreased in the groups receiving chemotherapy, particularly in the chemotherapy group （ P <0 05）; and also, the quality of life remarkably lowered in the chemotherapy group （ P <0 05）. Conclusion Chang’antai can markedly increase the patients’quality of life, decrease the toxic and side effects of chemotherapy, and enhance the ability of the liver to clear out CEA in the serum.关键词：Chang’antai;Carcinoma of Large Intestine;Metastasis;prevention
- 11
- |
- 241
- |
- 2
发布时间：2021-09-15 -
-
-
-
-
- 摘要：Objective To investigate the effects on uterine contraction of puncturing hegu and sanyinjiao with electric needles in rats in pregnancy at late stage. Method 36 healthy adult Wistar rats were divided into normal control group, model control group, hegu group, sanyinjiao group, and hegu plus sanyinjiao group （except for those in the normal control group, all rats were in pregnancy at late stage）; the intensity, frequency and strength of uterine contraction were used as the criteria in the observation. Results The effects of puncturing hegu with electric needles were persistent in a progressive manner, showing a rather strong aftereffect while the effects of puncturing sanyinjiao were only instant. At the same time, it was found that simultaneously puncturing hegu and sanyinjiao was not good for the two acupoints to exert their respective effects. Conclusion On the uterine contraction, the effects of puncturing hegu are not all as same as those of puncturing sanyinjiao, which suggests that when using hegu and sanyinjiao to induce or promote labor, hegu should be punctured first and then, sanyinjiao.关键词：Electric Acupuncture;Hegu;Sanyinjiao;uterine contraction;rat
- 10
- |
- 308
- |
- 19
发布时间：2021-09-15 - 摘要：Objective To compare the characteristics of different analgesic therapies. Method The pain related component P 250 -N 350 complex wave obtained by performing electroacupuncture to the posterior tibial nerve in normal human subjects was used as the criterion of pain; and the influences of different analgesic therapies on the changes in the amplitude and latent time of the P 250 -N 350 complex wave were observed. Results It was found that 30 minutes after intramuscular injection of tramadol the wave amplitude of P 250 -N 350 reached its lowest level. In the acupuncture drug group, the wave amplitude of P 250 -N 350 increased when the effect of tramadol became weak, but it declined again when acupuncture was given; in the acupuncture group, the wave amplitude of P 250 -N 350 markedly decreased （ P<0.001, P<0.05, P<0.001 ）; and in both groups regular changes in the latent time were not found. Conclusion The analgesic effects of acupuncture and those of drug therapy are basically identical, and a combined analgesic therapy of acupuncture and drug shows that acupuncture can prolong the acting time of an analgesic.关键词：Somatosensory Evoked Potential;Tramadol;acupuncture;Combined Analgesic Therapy of Acupuncture and Drug
- 8
- |
- 75
- |
- 1
发布时间：2021-09-15 - 摘要：Objective To investigate the specificity of the effects on auditory brainstem responses of different acupoints on the small intestine meridian of hand taiyang. Methods Guinea pig deafness model was induced by the injection of gentamicin; the acupoints of tinggong, jianzhen and houxi were chosen for a comparative study to observe their effects on the auditory brainstem responses. Results As far as the effects on the auditory brainstem responses were concerned, tinggong, as a periotic acupoint, was markedly stronger than both jianzhen and houxi while a comparison showed that houxi was a little bit stronger than jianzhen, although both of them did not show remarkably effects. Conclusion Not every acupoint on the small intestine meridian of hand taiyang has a correlation to the ear, and only the ones near the ear possess such a correlation.关键词：acupuncture;Small Intestine Meridian of Hand Taiyang;Auditory Brainstem Response;Specificity of Acupoint;guinea pig
- 9
- |
- 179
- |
- 3
发布时间：2021-09-15 - 摘要：Objective To investigate the mechanisms of the effects of acupuncture on mult infarct dementia （MID）. Method According to a TCM treating principle of supplementing the lower and clearing the upper to improve the mentality and enhance intelligence, a group of 46 MID cases was treated by acupuncture and a group of 30 MID cases treated by a drug therapy was used as a control. The curative efficacy was analyzed after one course of treatment. Results In the acupuncture group, 18 cases were fully cured and the cure rate was 39 13%, 24 cases responded to the treatment and the effective rate was 52 17%; the total effective rate was 91 3%; and as far as the effective rate was concerned, there was a significant difference between the acupuncture group and the control group. Analyses of HDS and FAQ scoring and neurographical malfunction scoring showed a mean effective rate of 84 25%, and the observation of the changes in dementia symptoms and the symptoms of the TCM syndromes differentiated showed a mean effective rate of 81 39%, which were better than those in the control group, indicating that acupuncture could improve mentality and the ability to take part in social activities, and relieve the clinical symptoms. And at the same time, the observation of the changes in the blood rheological criteria in 41 cases and the changes in the event related potential P 300 in 26 cases was carried out, and the results were statistically significant. Conclusion The acupuncture induced changes in hemodynamics and the restoration of the cerebral integration function through cerebral limbic system, may be important mechanisms of the effects of acupuncture in treating MID patients.关键词：Mult Infarct Dementia;vascular dementia;acupuncture;Acupuncture Clinical Practice
- 9
- |
- 250
- |
- 31
发布时间：2021-09-15 -
- Postal code：100029
- Tel：(010)53911857 Email：jbutcm@bucm.edu.cn
- Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19
京公网安备11010802024621 - It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
- Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.
0