最新刊期
卷 0 ， 期 1 ， 2004
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- 摘要：The authors hold that apoplexy is the fateful result of the accumulation of various endogenous and exogenous pathogenic factors, the decline of the resistance to disease, and the impairment due to pathogenic accumulation. As they accumulate in the body, the pathogenic factors activate and become toxic pathogens. Fatefully, apoplexy occurs, as the various toxic pathogens accumulate in the body by staying in blood vessels, and meridians and collaterals, which affects the brain and mentality. On the basis of understanding the accumulation of pathogens, therefore, the accumulation of toxic pathogens and the impairment due to the pathogenic accumulation can be considered as two basic pathogenic mechanisms of apoplexy in its development.关键词：Apoplexy;Toxic Pathogens;Toxic Pathogens Theory
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发布时间：2021-09-15 - 摘要：The key points of the differentiation and treatment of the invasion of collateral vessels by primary infection （ICVPI）, of which rheumatoid arthritis （RA） and severe acute respiratory syndrome （SARS） are two examples, are discussed in this paper. The authors hold that ICVPI starts in the level of ying and wei and develops in the level of qi and blood, and the cause of ICVPI is a combination of endogenous and exogenous pathogens. ICVPI can be chronic and acute, and the focus of ICVPI can be local and generalized. The authors put forward that the treating principle of ICVPI is to cut the route of the transmission of toxic pathogens at the early stage, and to unclog blood vessels consistently. In this paper, the authors investigate the mechanisms of ICVPI by studying the syndromes related with cold and heat and their treatment. The authors conclude that the differentiation and treatment of ICVPI is a worthy TCM approach to treating refractory diseases, such as RA and SARS.关键词：Invasion of Collateral Vessels by Primary Infection;rheumatoid arthritis;Severe Acute Respiratory Syndrome;Cold and Heat
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- 700
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发布时间：2021-09-15 - 摘要：In this paper, the difference and commonness between depression and TCM depression syndrome are discussed from on the basis of medical literature, clinical symptoms, etiology and pathogenesis. The authors hold that TCM depression syndrome include many diseases of various kinds of pathogenesis, including the disease caused by emotional factors. The description of depression in TCM is only the latter, and depression and the TCM depression syndrome should not be considered as the same. The authors put forward that in the TCM differentiation of depression, emphasis should be put on the aspect of deficiency, and the therapy of tonifying kidney and supplementing deficiency can achieve rather good clinical results in treating depression.关键词：depression;TCM Depression Syndrome;Correlational Study
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发布时间：2021-09-15 -
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- 摘要：Written at the beginning of the 11th century, the medical book Avicenna’s Canon of Medicine is one of important medical classics in world medical history. It was regarded as the medical guide in Europe, Arab countries and Northern African countries for a long time. This book was used as an authoritative textbook for more than 700 years in the mediaeval Europe. According to the statistics, the number of the reprinting times of Avicenna’s Canon of Medicine is only less than that of the Bible after the invention of typography. The author of Avicenna’s Canon of Medicine is Avicenna as the book’s title implies, who enjoyed a good reputation and was titled as Arab’s medical prince. Although American-European scholars have been paying great attention to the research of Avicenna’s Canon of Medicine, they have not known that there is much TCM content in it up to now. By studying Avicenna’s Canon of Medicine, we can know that the time of the introduction of TCM to Europe, which influenced the history of Western medicine, can be traced back to the 11th century, namely during the Song Dynasty of China. The study of Avicenna’s Canon of Medicine has found another important clue to the history of the medical exchange between the East and West.
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发布时间：2021-09-15 - 摘要：Written at the beginning of the 11th century, the medical book Avicenna’s Canon of Medicine is one of important medical classics in world medical history. It was regarded as the medical guide in Europe, Arab countries and Northern African countries for a long time. This book was used as an authoritative textbook for more than 700 years in the mediaeval Europe. According to the statistics, the number of the reprinting times of Avicenna’s Canon of Medicine is only less than that of the Bible after the invention of typography. The author of Avicenna’s Canon of Medicine is Avicenna as the book’s title implies, who enjoyed a good reputation and was titled as Arab’s medical prince. Although American-European scholars have been paying great attention to the research of Avicenna’s Canon of Medicine, they have not known that there is much TCM content in it up to now. By studying Avicenna’s Canon of Medicine, we can know that the time of the introduction of TCM to Europe, which influenced the history of Western medicine, can be traced back to the 11th century, namely during the Song Dynasty of China. The study of Avicenna’s Canon of Medicine has found another important clue to the history of the medical exchange between the East and West.关键词：Avicenna;Avicenna’s Canon of Medicine;Introduction of TCM to the West;World Medical History
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发布时间：2021-09-15 - 摘要：Objective To observe the effects of Banxiaxiexin Decoction （BD） and the effects of its different of ingredient groups on the rats with electrogastric dysrhythmia, in order to investigate the mechanism of removing mass and dispersing the accumulation of the formula of BD and the rule of composition of the formula. Methods The rat model of electrogastric dysrhythmia was established for detecting the effects of BD and its different groups of ingredients on the level of c kit positive ICC in stomach myenteric nerve plexus. Results There were significant differences between the effects of BD and its different ingredient groups and those of the control （ P <0 05）, especially between the effects of the pungent better ingredient group and the those of the control. Conclusion Both BD and its different ingredient groups can regulate the level of c kit positive ICC in stomach myenteric nerve plexus in varing degrees, and the pungent bitter ingredient group exerts the strongest effects. The results of the experiment can provide experimental evidence for further understanding the BD’s mechanism of regulating the function of qi through bitter descending and pungent dispersing actions.关键词：Banxiaxiexin Decoction;Level of c kit Positive ICC in Stomach Myenteric Nerve Plexus;Immunohistochemistry;TCM Formula Decomposition Study
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- 333
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发布时间：2021-09-15 - 摘要：Objective To observe the effects of Fullbone Capsules （FC） on the proliferation of cultured human osteobalstic sarcoma cell TE85 （HOS TE85） and on type I collagen synthesis （T I CS） in HOS TE85. Methods FC （1 10000 ug/L） was added into the HOS TE85 culture fluid and was cultured 24 hours, 48 hours, 72 hours and 96 hours, respectively. 3H thymidine was added into the HOS TE85 culture fluid 6 hours before finishing the culture to detect the proliferation of HOS TE85; 3H proline was added into the HOS TE85 culture fluid at the beginning of the culture to detect T I CS. Results FC could remarkably restrain the proliferation of HOS TE85 at the 48th hour and the 72nd hour, and markedly promote T I CS at the 48th hour, the 72nd hour and the 96th hour, with an obvious dose effect relationship.Conclusion FC exert effects of restraining the proliferation of HOS TE85 and promoting the T I CS, which may be FC’s mechanism of treating postmenopausal osteoporosis.关键词：Fullbone Capsules;Obsteoblast;proliferation;Type I Collagen
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发布时间：2021-09-15 - 摘要：Objective By observing the effects of Shenshuai Instant Granules （SIG） on the proliferation of renal fibroblasts （PRF） and on their TNF α secretion （TNF αS） in vitro, to explain SIG’s mechanism of relieving renal fibrosis. Methods Toxic serum and SIG medicated serum were prepared with the rats of renal failure. And the two kinds of serum were into the renal fibroblast culture fluid, and he changes in PRF and TNF αS were observed.Results The level of ET 1 in the rats of renal failure were decreased from 3055.74±166.65 to 1184.90±191.64 （ P <0.01） after SIG administration in vivo. PRF were decreased from 0.534±0.037 to 0.499±0.050 （ P <0.05）, and TNF αS were decreased from 8.33±1.48 to 5.70±0.69 （ P <0.01） after SIG administration in vitro.Conclusion SIG can restrain PRF, one mechanism of which may be related with decreasing TNF αS of the fibroblast through lowering the level of ET I .关键词：Shenshuai Instant Granules;fibroblast;TNF α
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发布时间：2021-09-15 - 摘要：Objective To investigate the effects of Anti Osteoporosis Acupoint Plaster （AOAP） on experimental osteoporosis （EO）, and its mechanism of antagonizing the development of osteoporosis. Methods The rat model was established by intramuscular dexamethasone injection. The model rats were treated with AOAP by plastering the plaster on the selected acupoints and on the selected non acupoints, with drugs for tonifying the kidney as a control. The serum T/E2, bone density, CT/PTH, and the bone morphometrical indexes, such as TBV, TBS, TFS, LBGR, AFS, MAR, BFR, TRS were used as the criteria in observing the effects of AOAP.Results AOAP could increase the bone density and the levels of serum T/E2 and CT/PTH, raise the levels of TBV, TBS, TFS, LBGR, AFS, MAR and BFR, and reduce the level of TRS.Conclusion AOAP can regulate and control the incretion related with bone metabolism by multiposition correlational aggregative effect, raise the levels of T/E2 and CT/PTH, avoid the calcium loss in osteoporosis and increase bone density.
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发布时间：2021-09-15 - 摘要：Objective To study the pH dependence of Changankang Capsules （CC） through their drug release investigation in vitro.Methods HPLC method was used in the experiment, and the levels of berberine hydrochloride （BH） in the simulated gastric fluid （SGF） and the simulated intestinal fluid （SIF） were taken as the criteria to evaluate CC’s pH dependent drug release in vitro.Results After being treated with the acrylic resin enteric coating, CC showed certain slow released action, with about a release of 17% in SGF after 1 hour, and with about a complete release in SIF after 5 hours. Conclusion The results of this experiment show that the technology of treating CC with acrylic resin enteric coating is feasible. It can be predicted that BH may be rich in the colon.关键词：Changankang Capsules;berberine hydrochloride;HPLC
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发布时间：2021-09-15 - 摘要：Objective To observe the effects of Tongmaiyizhi Capsules （TCs） on the middle cerebral artery in the rabbits with atherosclerosis. Methods 21 Healthy Japanese male rabbits were randomly divided into three groups according to their body weights. After 12 weeks of the experiment, the pathologic changes in the middle cerebral artery were observed with the light microscope, and the pathologic changes in the endothelial cells of the middle cerebral artery were observed with the scanning electron microscope. Results TCs showed obvious effects of protecting the endothelial cells of the middle cerebral artery and the effects of inhibiting the proliferation of vascular smooth muscle cells. Conclusion TCs possess rather good effects of protecting the middle cerebral artery, which may be related to their actions of protecting vascular endothelial cells and inhibiting the proliferation of vascular smooth muscle cells.关键词：atherosclerosis;Tongmaiyizhi Capsules;Middle Cerebral Artery;rabbit
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发布时间：2021-09-15 - 摘要：Objective To investigate the effects of Compound Gingko Guttate Pills （CGGPs） against thrombosis and platelet aggregation. Methods Rats were used to establish the model of artery vein bypass thrombosis and the thrombus weight （either wet or dry） was measured. Collagen, platelet active factor and adenosine diphosphate were used to induce platelet aggregation in the guinea pigs and the ratio of platelet aggregation in different times and the maximum ratio of platelet aggregation were detected. Results All CGGPs doses （40 mg/kg, 20 mg/kg, 10 mg/kg） could inhibit artery vein bypass thrombosis in different degrees, reduce thrombus weight （either wet or dry, P<0 05, P <0 01） in rats; and inhibit platelet aggregation with different revulsant in different times, and reduce the maximum ratio of platelet aggregation in guinea pigs. Conclusion CGGPs exert remarkable effects against thrombosis and possess strong effects against platelet aggregation in a large scope.关键词：Compound Gingko Guttate Pills;Thrombosis;Platelet Aggregation
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发布时间：2021-09-15 - 摘要：Objective To study the effects of Zhouluotong, a TCM compound preparation, on the function of sciatic nerve, the activity of aldose reductase and the ability of aldose reductase against free radicals in the rats with diabetes. Methods The rat model of STZ induced diabetes was orally given Zhouluotong for 8 weeks, in order to observe its effects on the conduction velocity of the sciatic never, on the activities of Na +,K + ATPase, aldose reductase, SOD, GSH PX and CAT in the sciatic nerve tissue, and on the levels of MDA and GSH in the sciatic never tissue.Results It was found that Zhouluotong had no marked effects on the body weight and the level of blood sugar in the rats with STZ induced diabetes while this TCM preparation could markedly improve the conduction velocity of rat sciatic nerve and enhance the activity of Na +,K + ATPase. In addition, Zhouluotong could remarkably inhibit the increase in the activities of aldose reductase, SOD and CAT, enhance the activity of GSH PX and reduce the level of MDA. Conclusion Inhibiting the enhancement of the polyol pathway and reducing the injuries due to free radicals may be important mechanisms of Zhouluotong in the prevention and treatment of diabetic peripheral neuropathy.
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发布时间：2021-09-15 - 摘要：Objective To initially investigate the possible antianxietic mechanism of Suanzaoren Decoction （SD）.Methods The elevated plus maze test （EPM）, an internationally universal anxiety model, was used to observe the effects of SD on serum NO and the cytokines, such as IL 1β, IL 6 and TNFαin the rats with EPM.Results It was found that SD could increase the level of serum NO, and restrain the decrease of the levels of IL 1β and TNF α.Conclusion The mechanism of the antianxietic effects of SD may be related to the regulation of the levels of serum NO and cytokines, such as IL 1β and TNF α.关键词：Suanzaoren Decoction;EPM;NO;cytokine;rats
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发布时间：2021-09-15 - 摘要：Objective To study the chemical components of Dryopteris crassirhizoma （DC）. Methods GC MS chromatograph was used to analyze and identify the components of the oil like mixture extracted by the silica gel column chromatography from DC.Results A oil like mixture was obtained from part A of the anti malarial fraction by the silica gel column chromatography, and 17 chromatographic peaks were obtained from the oil like mixture by using the GC MS chromatograph and 12 components were identified. Conclusion The 12 components are butyl-cyclohexane; cis-decahydro-naphthalene; 1-methylethy1-cyclohexane; 9-（1-methylidene）-bicyclo[6.1.0]nonane; cyclohexy1-cyclohexane; （-）-3,7,7-trimethy1-11-methylene-spiro[5.5]undec-2-ene; [1S-（1α, 3aβ, 4α, 8aβ）]-decahydro-4,8,8-trimethy1-9-methylene-1,4-methanoazulene; 3,7,11-trimethy1-2,6,10-dodecatrien-1-ol; caryophyllene; 2,3,4,4a,5,6-hexahydro-1, 4a-dimethy1-7-（1-methylethy1）-naphthalene; [1aR-（1aα,7α,7aα,7bα）]-1a,2,3,5,6,7,7a,7b-octathydro-1,1,7,7a-tetramethy1-1H-cyclopropa[a]-naphthalene; and α-curcumene, respectively. All these components are extracted and identified from the plant for the first time.关键词：Dryopteris Crassirhizoma;chemical component;Anti Malarial Activity
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发布时间：2021-09-15 -
Quantitative Determination of Neohesperidin in the Antidepressive Fraction of Sini Powder by RP-HPLC
摘要：Objective To establish a method for quantitative determination of neohesperidin in the antidepressive fraction of Sini Powder by RP HPLC.Methods YWG C18 chromatographic column （250 mm×4.6 mm, 10 μm） was chosen, the mobile phase was acetonitrile : 0.1% aqueous solution of phosphoric acid （20:80）, the detection wavelength was 283 nm, and the column was at a room temperature. Results There was a good linear relationship between the quantities of the neohesperidin sample （from 0.0816 μg to 0.4896 μg.） and their peak areas （r=0.9995）, and the average recovery was 97.10% （RSD=0.86%, n=5）. Conclusion This method is simple, accurate and reliable, and can be used to control the quality of the antidepressive fraction of Sini Powder.关键词：Sini Powder- 12
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发布时间：2021-09-15 -
Quantitative Determination of Neohesperidin in the Antidepressive Fraction of Sini Powder by RP-HPLC
摘要：Objective To establish a method for quantitative determination of neohesperidin in the antidepressive fraction of Sini Powder by RP HPLC.Methods YWG C18 chromatographic column （250 mm×4.6 mm, 10 μm） was chosen, the mobile phase was acetonitrile : 0.1% aqueous solution of phosphoric acid （20:80）, the detection wavelength was 283 nm, and the column was at a room temperature. Results There was a good linear relationship between the quantities of the neohesperidin sample （from 0.0816 μg to 0.4896 μg.） and their peak areas （r=0.9995）, and the average recovery was 97.10% （RSD=0.86%, n=5）. Conclusion This method is simple, accurate and reliable, and can be used to control the quality of the antidepressive fraction of Sini Powder.关键词：Sini Powder;Neohesperidin;RP HPLC- 12
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发布时间：2021-09-15 -
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- 摘要：Objective To investigate the relationship between the TCM syndromes in acute cerebral infarction and the two biochemical criteria, tissue plasminogenemia activator （t PA） and plasminogenemia activator inhibitor （PAI） in the plasma. Methods Clinical observation was carried out according to the TCM diagnostic criteria for selecting the cases, and observation forms were filled accordingly. The data were statistically analyzed. Results There was a significant difference between the level of tPA in the qi deficiency group and that in other groups （ P <0.01）; however, there was no significant difference between the level of tPA in the qi deficiency group and that in both the qi deficiency and blood stagnation group and the qi yin deficiency group （ P >0.05）; again, there was a significant difference between the level of PAI in the qi yin dificiency group and that in other groups （ P <0.01）. The results of the observation showed that tPA and PAI were closely correlated, with r=0.827. Conclusion Both tPA and PAI are markers of endothelial injuries, and they are the relatively specific criteria for diagnosing TCM blood stagnation syndrome.关键词：cerebral infarction;TCM syndrome;clinical research;Tissue Plasminogenemia Activator;Plasminogenemia Activator Inhibitor
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发布时间：2021-09-15 - 摘要：Objective To initially investigate the effects of the combination of Fritillaria Thunbergii Bulb Powder （FTBP） and chemotherapeutics for reversing the higher expression of P 170 and its clinical prospect of application. Methods The expression of P 170 in the patients with acute leukemia was detected by flow cytometry, and the P 170 positive cases were treated with the combination of FTBP and chemotherapeutics in order to carry out the clinical study of reversing multidrug resistance.Results It was found that the higher expression of P 170 could be reversed by the combination of FTBP and routine chemotherapeutics in which the FTBP was used in a clinically safe dose. The combination use of FTBP with routine chemotherapeutics could decrease the percentage of the marrow primordial cells and might increase the clinical complete remission ratio.Conclusion FTBP may become a safe and effective drug for reversing multidrug resistance, and has a rather big value to be promoted into clinical application for treating the patients with acute leukemia characterized by higher expression of P 170 .关键词：Acute Leukemia;P Glycoprotein;Fritillaria Thunbergii Bulb Powder;multidrug resistance;Reversion
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发布时间：2021-09-15 - 摘要：Objective To investigate the protective effect of Xinmaitong Capsules （XC） on stunned myocardium and the mechanism of the effect in the patients with acute myocardiac infarction （AMI）. Methods 46 cases of AMI were randomly divided into the XC group （23 cases, treated with regular western-style medicine and XC） and control group （23 cases, treated with regular western-style medicine only）. The systolic function and the dyskinetic index of the ventricular wall were observed in the AMI patients before and after the treatment.Results There was a significant difference between the improvement of the motor function of the left ventricle and the decrease of the dyskinetic index of the ventricular wall in the XC group and those in the control group （ P <0 05）.Conclusion XC possess marked effect on the restoration of the motor function of stunned myocardium in the AMI patients.关键词：Xinmaitong Capsules;Acute Myocardiac Infarction;Stunned Myocardium
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发布时间：2021-09-15 - 摘要：Objective To investigate the mechanism of effects of the TCM therapy of clearing lung and harmonizing stomach in the treatment of gastric internal impairment complicated by the cough caused by exogenous pathogens.Methods 90 Cases of gastric internal impairment complicated by the cough caused by exogenous pathogens were randomly divided into 3 groups: the treating group treated by the therapy of clearing lung and harmonizing stomach （with a self-designed decoction ）, the control group-1 treated by the therapy of treating both the lung and stomach （with Jizhi Syrup and the Modified Baohe Pills）, and the control group-2 treated by therapy of treating the lung only （with Jizhi Syrup only）; the treatment course was equally 7 days for all the three groups. Results The TCM therapy of clearing lung and harmonizing stomach showed much better effects than other therapies used in the clinical trial, as far as the relief of the clinical symptoms and the shortening of the treatment course were concerned （ P <0.01）, which suggested that the therapy and the relevant formula were feasible and possessed a relatively high clinical value. Conclusion In the treatment of the cough caused by exogenous pathogens, the key points are careful differentiation of gastric internal impairment, clearly understanding of the pathogenesis, and a perfect unison of the prescribed drugs and the diagnosed syndromes.关键词：Gastric Internal Impairment;Cough Caused by Exogenous Pathogens;Therapy of Clearing Lung and Harmonizing Stomach
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发布时间：2021-09-15 - 摘要：Objective To observe the effects of the combined therapy of Yiqijiedu Formula （YF） and acyclovir eyedrops （AE） in the treatment of recurrent herpes simplex keratitis （RHSK）. Methods The treating group （60 cases, 67 eyes） was given YF and AE, the control group 1 （38 cases, 43 eyes） was given Yinqiao Powder and AE, and the control group 2 （34 cases, 38 eyes） vitamins and AE. The cured patients were paid a one year follow up survey.Results The treating group manifested better effects than the control groups, as far as the morbid duration and the curative efficacy were concerned （ P <0.01）. The results of the follow up survey paid to the cured patients showed that the recurrent rate was much lower in the treating group than that in the control groups （ P <0.01）, and however, there was no significant difference between the recurrent rates in the two control groups （ P >0 05）.Conclusion YF shows good effects in the treatment of RHSK, and it shortens the morbid duration and reduces the recurrent rate.关键词：Recurrent Herpes Simplex Keratitis;TCM Drugs for Nourishing Qi and Neutralizing Toxins;Acyclovir Eyedrops
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发布时间：2021-09-15 - 摘要：Objective To observe the effects of the combined therapy of Yiqijiedu Formula （YF） and acyclovir eyedrops （AE） in the treatment of recurrent herpes simplex keratitis （RHSK）. Methods The treating group （60 cases, 67 eyes） was given YF and AE, the control group 1 （38 cases, 43 eyes） was given Yinqiao Powder and AE, and the control group 2 （34 cases, 38 eyes） vitamins and AE. The cured patients were paid a one year follow up survey.Results The treating group manifested better effects than the control groups, as far as the morbid duration and the curative efficacy were concerned （ P <0.01）. The results of the follow up survey paid to the cured patients showed that the recurrent rate was much lower in the treating group than that in the control groups （ P <0.01）, and however, there was no significant difference between the recurrent rates in the two control groups （ P >0 05）.Conclusion YF shows good effects in the treatment of RHSK, and it shortens the morbid duration and reduces the recurrent rate.
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发布时间：2021-09-15 - 摘要：Objective To study the correlation between pathogenic cold and meteorologic factors and find out the quantitative relationship between them. Methods SPSS was used to statistically analyze the patients with chronic bronchitis treated in the affiliated hospital of Shandong University of Traditional Chinese Medicine and the meteorologic material from 1997 to 2000, to calculate the correlative coefficient of pathogenic cold and meteorologic factors in Jinan area and to establish the relevant regression equation.Results It was shown that there were remarkable correlations between pathogenic cold and the monthly average temperature, monthly lowest temperature and monthly average atmospheric pressure; the first two indexes showed negative correlation with pathogenic cold and the last index showed positive correlation with pathogenic cold.Conclusion Mainly, pathogenic cold is close correlated with the meteorologic factors related to environmental temperatures.关键词：chronic bronchitis;pathogenic cold;Meteorologic Factors;Correlative Analysis
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发布时间：2021-09-15 - 摘要：Objective To study the correlation between pathogenic cold and meteorologic factors and find out the quantitative relationship between them. Methods SPSS was used to statistically analyze the patients with chronic bronchitis treated in the affiliated hospital of Shandong University of Traditional Chinese Medicine and the meteorologic material from 1997 to 2000, to calculate the correlative coefficient of pathogenic cold and meteorologic factors in Jinan area and to establish the relevant regression equation.Results It was shown that there were remarkable correlations between pathogenic cold and the monthly average temperature, monthly lowest temperature and monthly average atmospheric pressure; the first two indexes showed negative correlation with pathogenic cold and the last index showed positive correlation with pathogenic cold.Conclusion Mainly, pathogenic cold is close correlated with the meteorologic factors related to environmental temperatures.关键词：chronic bronchitis;pathogenic cold;Meteorologic Factors;Correlative Analysis
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发布时间：2021-09-15 - 摘要：Objective To study the effects of soybean isoflavones on the menopausal symptoms and the secretion of sex hormones. Methods The levels of follicle stimulating hormone （FSH）, luteotropic hormone （LH）, progesterone, testosterone, prolactin （PRL） and estradiol-17 （E 2） were measured in the serum in the menopausal, perimenopausal and postmenopausal women after they were administered soybean isoflavones for 6 weeks, and at the same time, the relief of the symptoms were observed, such as menopausal flushing, simultaneous sweat and night sweat, vexation and anxiety, insomnia and dream disturbed sleep, dizziness and tinnitus.Results The levels of FSH and LH were decreased and the levels of PRL and E 2 were increased in the group of women aged 35～45, 46～55 and 56～65, after being administered soybean isoflavones; and the symptoms in the group of women aged 46～55 and 56～65 were all relieved in a certain degree.Conclusion Soybean isoflavones can decrease the levels of FSH and LH and increase the levels of PRL and E 2 in the serum in the menopausal, perimenopausal and postmenopausal women, and the changes in the levels of hormones due to soybean isoflavones are more obvious in the group of younger women; furthermore, soybean isoflavones show an effect of relieving menopausal symptoms.
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发布时间：2021-09-15 - 摘要：Objective To study the effects of soybean isoflavones on the menopausal symptoms and the secretion of sex hormones. Methods The levels of follicle stimulating hormone （FSH）, luteotropic hormone （LH）, progesterone, testosterone, prolactin （PRL） and estradiol-17 （E 2） were measured in the serum in the menopausal, perimenopausal and postmenopausal women after they were administered soybean isoflavones for 6 weeks, and at the same time, the relief of the symptoms were observed, such as menopausal flushing, simultaneous sweat and night sweat, vexation and anxiety, insomnia and dream disturbed sleep, dizziness and tinnitus.Results The levels of FSH and LH were decreased and the levels of PRL and E 2 were increased in the group of women aged 35～45, 46～55 and 56～65, after being administered soybean isoflavones; and the symptoms in the group of women aged 46～55 and 56～65 were all relieved in a certain degree.Conclusion Soybean isoflavones can decrease the levels of FSH and LH and increase the levels of PRL and E 2 in the serum in the menopausal, perimenopausal and postmenopausal women, and the changes in the levels of hormones due to soybean isoflavones are more obvious in the group of younger women; furthermore, soybean isoflavones show an effect of relieving menopausal symptoms.
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发布时间：2021-09-15 -
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