最新刊期
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- 摘要：The nomenclative principles were founded according to the nomenclative stipulation of scientific and technological terms. The diagnostic method chapters in Diagnosis of Chinese Medicine, to be a standard teaching material, were taken as the research objects, and there were 7 problems found out and some suggestions were put forward as follows: Complementing faulty symptom names; ② Simplifying a complex clinical description （with a single attribute） to define symptom names; ③ Separating clinical descriptions （with multiple attributes） to define symptom names; ④ Combining the symptom names with the same or similar connotation; ⑤ Separating the symptom name with different clinical manifestations and diagnostic meanings; ⑥ To reveal a special diagnostic meaning by assembling multiple symptoms not belong to the diagnostic method; ⑦ Deleting the symptom names of Western medicine.
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发布时间：2021-09-15 -
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- 摘要：The current situation of micro-viewed study on the syndrome of spleen-qi deficiency were outlined here and a few key questions in the essence of TCM syndromes were analyzed emphatically, such as the multiple morphs of zang-organ manifestations, the same and different characteristics in zang-organ manifestation research and syndrome research, macro-viewed standard of syndrome differentiation, and orientation of micro-viewed study. In research practice the possible solution strategies were introduced, including the reification of TCM concept units, idea of hierarchy based on systematic science, mutual-complementary research orientation, and more attention to the relationship among various indexes.
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发布时间：2021-09-15 - 摘要：Objective To study the relationship between different pulse forces and radial cyclic kinetic energy （CKE） of transverse section of radial artery.Method A new-type sphymograph was applied to collect synchronously the pressure phygmograms of guan pulse, signals of ECG and dynamic ultrasound images of transverse section of radial artery in 39 patients and 20 healthy persons.On the basis of images analysis with the software of MATLAB 7.0.1 the changes of axis traces of transverse section of radial artery in different pulse forces were observed and the radial CKE was calculated.Result There was a significant difference in radial CKE among different pulse forces and manifestations.The relation between CKE and different pulse forces and manifestations showed as pulse tracings with powerful force>pulse tracings with normal force>pulse tracings with weak force.Conclusion The radial CKE of transverse section of radial artery may be the base for distinguishing different pulse forces.关键词：pulse force;type-B ultrasonic examination;Radial Artery;axis;cyclic kinetic energy
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发布时间：2021-09-15 - 摘要：Objective To compare 3 tongue manifestations of rat model of cerebral ischemia in order to select the right model of cerebral ischemia for reducing biological exosymptom of blood-stasis syndrome. Methods These models of cerebral ischemia were selected, including the model of middle cerebral artery occlusion （MCAO, group 1）, model of bilateral common carotid artery （BCCA, group 2） and model of unilateral common carotid artery ligation （UCCA, group 3）, and then the chroma value of tongue texture and scores of hypoglossis vein length were compared at different time points after cerebral ischemia （on 1st, 3rd, 5th and 7th day）.Results There was a statistical difference （P<0.05） in the chroma value of tongue texture among group 1, group 2 and normal group 3 or 5 days after cerebral ischemia.The chroma value of tongue texture of group 1 （147.41±13.32） and group 2 （147.57±14.53） reached the highest point at different time points within the group 3 days after cerebral ischemia, but there was no statistical difference （P>0.05）. The mean value of scores of hypoglossis vein length in group 1 （1.44±0.08） was higher then that of the normal group （0.56±0.53） 3 days after cerebral ischemia with a statistical difference （P<0.05）.Conclusion Among 3 models of cerebral ischemia MCAO model may be the most appropriate model of cerebral ischemia for inducing biological exosymptom of blood-stasis syndrome.关键词：model of cerebral ischemia;blood-stasis syndrome;chroma value of tongue texture;rats
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发布时间：2021-09-15 - 摘要：Objective To establish a method for determination the contents of amino acid-like neurotransmitter in cerebrospinal fluid （CSF） of amyotrophic lateral sclerosis （ALS） patients.The changes of amino acid-like neurotransmitter in CSF were observed in the patients before and after the treatment with Jiweiling Injection.Method The CSF were collected from 42 patients, in which the contents of aspartic acid, glutamic acid, glycine and γ-Aminobuyric acid were detected with HPLC of OPA pre-column derivation.Result Above four kinds of amino acid were separated well with a good linear relationship within 20 minutes.After the treatment in 42 patients the contents of aspartic acid and glutamic acid were decreased significantly, while those of glycine and γ-Aminobuyric acid did not change.Conclusion The method can be performed rapidly and accurately with a higher sensitivity. It can be used in the quantitative determination of amino acid-like neurotransmitter in CSF.关键词：HPLC;pre-column derivation;cerebrospinal fluid;Amino Acid;amyotrophic lateral sclerosis
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发布时间：2021-09-15 - 摘要：Objective To discuss the relationship between Evans blue and the changing rules of exosymptoms of animal model with blood-stasis syndrome induced by macromolecular dextran in different concentrations.Method The rat model was established by using different concentrations of macromolecular dextran （5%, 10% and 15% compounded with 0.5% Evans blue）.The exosymptom changes presented by Evans blue in ear and tongue body of rat model with blood-stasis syndrome induced by macromolecular dextran were observed and the contents of Evans blue in the ear and plasma were detected.Result After one hour there were blue ecchymosis in different degrees in model ear and tongue body in different groups injected different concentrations of macromolecular dextran.The ecchymosis was correlated with the concentration of macromolecular dextran.Comparing to the rats in the control group the rats in different macromolecular dextran groups had a higher content of Evans blue in ear with a higher concentration of macromolecular dextran, while the content of plasma Evans blue decreased when the concentration of macromolecular dextran increased.Conclusion The model rats injected in caudal vein with different concentrations of macromolecular dextran （compounded with 0.5% Evans blue） can present the exosymptoms in the ear and tongue body directly.The content changes of plasma Evans blue in the ear and tongue body are correlated with the degree of blood stasis at the same time, which indicates that Evans blue can reflect objectively the exosymptom changes in rat model of blood-stasis syndrome induced by macromolecular dextran.关键词：blood-stasis syndrome;Evans blue;macromolecular dextran;exosymptom;rats
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发布时间：2021-09-15 - 摘要：Objective Along with the development of sciences and technology it is the most important task for TCM standardization that the appropriate calculative method is chosen to differentiate TCM syndromes in today with the cross of multiple disciplines.It is the most important task in TCM that symptom group containing the most information is chosen to be differentiated.Method The feature selection based on mutual information was combined with multi-class support vector machines （SVM）, which then was treated by multiple source data of feature selection for getting the symptom groups with most information.These groups were used as the inputs of multi-class SVM for classification and then the appropriate syndromes were gained according to the outputs of SVM. The efficiency of the method was approved through analyzing a TCM example.Result The optimum symptom group was get by the feature selection based on mutual information through the comparison of correct rate in the syndrome differentiation of symptom groups selected by different methods.Conclusion The result shows that the symptom group selected by feature selection is better than that selected by simple selection based on mutual information. The outcomes from the study also showed that SVM is suitable to the small sample study of TCM syndromes, which indicates that the combination of mutual information, feature selection and SVM is the same with TCM syndrome differentiation and classification.关键词：TCM syndrome differentiation;feature selection;support vector machines;mutual information
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发布时间：2021-09-15 - 摘要：Objective To study the chemical constituents of supercritical CO2 extract from Valeriana jatamansi and their relative contents.Methods The distilled oil from Valeriana jatamansi were extracted by supercritical CO2 extraction, and the chemical constituents and relative contents were determined by GC-MS, and identified by searching MS database and referring to related documents.Results The yield of extractive rate was 8.85%.There were 80 components separated, among which 74 were identified and analyzed.Conclusion Supercritical CO2 extraction increases the extractive rate of distilled oil from Valeriana jatamansi and reserves the original constituents. The method can be spread to the research, development and extraction of Valeriana jatamansi.关键词：Valeriana jatamansi;distilled oil;GC-MS;chemical constituents
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发布时间：2021-09-15 - 摘要：Objective To find out the best condition for the self-emulsifying formula of thyme aetherolea.Methods The oil, non-ionic surfactant and co-surfactant were screened for the best formula through solubility experiment, orthogonal screen and drawing phase diagram, taking the emulsifying degree and effective diameter as indexes.Results The oil in the self-emulsifying formula of thyme aetherolea was ethyl oleate and surfactant was cremophor EL.The best proportion range was from 4∶6 to 6∶4.ConclusionThe best formula for self-emulsification of thyme aetherolea is consisted of thyme aetherolea, ethyl oleate and cremophor EL, and the best proportion of them is 2∶5∶5.关键词：thyme aetherolea;SEDDS;improvement of medical preparation
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发布时间：2021-09-15 - 摘要：Objective To investigate the influence of Danggui Injection and Huangqi Injection on the angiogenesis of chick chorioallantois.Methods The chick chorioallantois model was established by incubating fertilized eggs at 37.8℃ for 7 days.Danggui Injection and Huangqi Injection with various ratios were dropped on the carrier of chorioallantois and then the eggs were continuously incubated for 3 days. The survival status of chick was observed and the chick chorioallantois sample was prepared, and then the number of new capillaries was counted by using anatomic microscope.Results Danggui Injection and Huangqi Injection with various ratios all promoted the angiogenesis of chick chorioallantois with a significant difference（P<0.05） compared with normal saline solution.Except of ratio of 1 to 5 between Danggui Injection and Huangqi Injection, other ratios had lower efficacies than epidermal growth factors （EGF,P<0.05）. Conclusion Danggui Injection and Huangqi Injection with various ratios have a significant promoting effect on the angiogenesis of chick chorioallantois. The mechanism may be related to the proliferation and migration of vascular endothelial cells.关键词：angiogenesis;chick chorioallantois;Danggui Injection;Huangqi Injection
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发布时间：2021-09-15 - 摘要：Objective To study the correlation between TCM syndromes of coronary heart disease （CHD） and the pathologic degree of the coronary artery.Method The coronary arteriongraphy （CAG） was given to 168 in-patients, and their disease history, symptoms, signs, tongue-pulse manifestations and results of laboratory examination were recorded.After TCM syndrome differentiation and classification, there were 7 syndromes taken as independent variables, and the total grades of Gensini or the pathologic number of coronary artery as dependent variable analyzed by multiple linear-regression.Results The cold-accumulation syndrome, sputum-turbid syndrome and yin-deficiency syndrome were all correlated to the total grades of Gensini and the pathologic number of the coronary artery.The blood-stasis syndrome was correlated to the pathologic number of the coronary artery.Conclusion The cold-accumulation syndrome, sputum-turbid syndrome, yin-deficiency syndrome and blood-stasis syndrome are all correlated to the pathologic degree of the coronary artery, which play an important role in the indication of CHD development.关键词：coronary heart disease;syndromes;pathologic degree of the coronary artery;total grades of Gensini
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发布时间：2021-09-15 - 摘要：Objective To evaluate the influence of Tangzhiping Capsules on the conversion from impaired glucose tolerance （IGT） to type 2 diabetes mellitus.Method The prospective study was conducted by the random two-blind control experience in 210 IGT cases diagnosed according to WHO standard. The cases were randomly divided into 3 groups and were treated with placebo （group 1）, Tangzhiping Capsules （group 2） and Acarbose （group 3） respectively and observed for 2 years based on the interference of life style.The observation indexes included the indexes of OGTT, BMI, blood pressure, blood fat and insulin resistance （IR）.Result In group 1 the indexes of FPG, 2hPG of OGTT, HbA1c and IR were all increased significantly and the average annual morbidity of diabetes was 11.72 %.In group 3 the indexes of FPG, 2hPG of OGTT and HbA1c were all decreased significantly and the average annual morbidity of diabetes was 3.18 %.The relative risk rate of group 3 was decreased by 72.87 % compared with that of group 1.In group 2 the indexes of FPG, 2hPG of OGTT, HbA1c and IR were all decreased significantly and the average annual morbidity of diabetes was 5.39 %.The relative risk rate of group 2 was decreased by 54.01 % compared with that of group 1.Conclusion Tangzhiping Capsules can decrease the indexes of FPG and 2hPG, improve IR and induce significantly the relative risk rate of conversion from IGT to diabetes.关键词：Tangzhiping Capsules;impaired glucose tolerance;type 2 diabetes;chinical observation
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发布时间：2021-09-15 - 摘要：Objective To evaluate the efficacy and safety of Qianlie Decoction in treating chronic pelvic pain syndrome （CPPS, TCM syndrome of damp-heat and blood-stasis obstruction）.Methods The patients （n=142） were randomly divided into the treatment group treated with Qianlie Decoction （1 dose daily taken by 2 times）, and the control group was treated with Celecoxib Capsules （200 mg once daily）.The treatment course was for 4 weeks in two groups.The count of WBC and SPL in EPS were detected before and after the treatment.The scores of NIH-CPSI and TCM syndromes, and the difference between tow groups were compared and evaluated before and after the treatment.Results After the treatment In the treatment group the scores of NIH-CPSI was induced by 11, scores of TCM syndromes, by 14.14 and WBC, by 5.86.In the control group the scores of NIH-CPSI was induced by 9.85, scores of TCM syndromes,by9.80 and WBC, by 7.76.The difference in all indexes in two groups was statistically significant before and after the treatment （P<0.01）.The difference between 2 groups was not significant statistically （P>0.05）.SPL counts were all increased significantly in two groups （P<0.01）, and the result of the treatment group was better than that of the control group （P<0.01）.The difference between two groups in the curative effect on CPPS （TCM syndrome of damp-heat and blood-stasis obstruction） was not statistically significant（P>0.05）.Conclusion Qianlie Decoction is efficacious and safe for treating CPPS （TCM syndrome of damp-heat and blood-stasis obstruction）.关键词：chronic pelvic pain syndrome;Qianlie Decoction;syndrome of damp-heat and blood-stasis obstruction;clinical experiment
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发布时间：2021-09-15 - 摘要：Objective To study the symptom distribution and characteristics of the syndrome of liver-depression and spleen-deficiency.Method The method of clinical epidemiology-DME were used to survey the experts in 15 TCM hospitals.Results The most common symptoms of the syndrome of liver-depression and spleen-deficiency were wiry pulse, distension and fullness in chest and hypochondrium, reduced appetite, whitish tongue coating and fatigue.Conclusion The results of the questionnaire are in accord with the basic theory of TCM,which has laid a foundation for the further investigation in patients.关键词：syndrome of liver-depression and spleen-deficiency;symptoms;expert-questionnaire
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发布时间：2021-09-15 - 摘要：Objective To evaluate the curative effect and safety of Bushenqiangdu Formula on ankylosing spondylitis （AS, TCM syndrome of kidney-deficiency, Du-cold and blood-stasis）.Methods The patients with ankylosing spondylitis （TCM syndrome of kidney-deficiency, Du-cold and blood-stasis） were divided into the treatment group treated with Bushenqiangdu Formula and the control group treated with Wangbi Granules combined with total glucosides of white peony. The changes of symptoms, TCM syndrome scores, signs and indexes of laboratory examination in two groups were observed. The effectual rate, effective rate and total effective rate were calculated in two groups. The side effects were observed and the mechanism of Bushenqiangdu Formula was discussed.Results After the treatment the symptoms of the patients in two groups were relieved and the integral of blood-stasis syndrome were obviously induced.The outcomes of laboratory examination in two groups were improved remarkably. The indexes of ESR, CRP, monocytes count of peripheral blood, platelet count, IgA and IgG were all improved.The effectual rate of Bushenqiangdu Formula on AS was 30 %, effective rate, 56.67 % and total effective rate, 86.67 %.Conclusion Bushenqiangdu Formula has the effects of anti-inflammation, activating blood circulation to remove stasis,and immunoregulation with a higher total effective rate, safety and without side effects.关键词：ankylosing spondylitis;syndrome of kidney-deficiency, Du-cold and blood-stasis;Bushenqiangdu Formula;clinical study
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发布时间：2021-09-15 - 摘要：Objective To discuss in the first part four acupuncture plans, including "resuscitation inducing technique" "needling Baihui （DU20） through Qubin （GB7）","Jiao’s three-needle technique" and "temporal three-needle technique" brought into the clinical research literature about ischemic cerebrovascular disease. The number of articles, authors and impact factors of the journals in which the articles were published were analyzed.Methods The number of clinical research literature about the four acupuncture plans, the number of articles and authors brought into the literature, the impact factors of the journals related to the literature were described and analyzed statistically by using employing rate and constituent ratio. Results The ratio of appropriate articles was lower in collected literature.The percentage showed that Jiao’s three-needle technique was 0.15 %,resuscitation inducing technique, 0.27 %, needling Baihui （DU20） through Qubin （GB7）, 1.79 %, temporal three-needle technique, 1.3 %.The ratio of 3 authors or more of an article was higher.The percentage showed that resuscitation inducing technique was 50 %, needling Baihui （DU20） through Qubin （GB7）, 50 %, temporal three-needle technique, 62.5 % and Jiao’s three-needle technique,30 %.The ratio of resuscitation inducing technique and needling Baihui （DU20） through Qubin（GB7） in the impant factors of the journals （over 0.5） was higher respectively.The percentage showed that resuscitation inducing technique was 40 %, needling Baihui （DU20） through Qubin （GB7）, 50 %, temporal three-needle technique, 12.5 % and Jiao’s three-needle technique, 10 %.Conclusion It is suggested that multiple cooperation should be carried out in the clinical study of the four acupuncture techniques in the treatment of ischemic cerebrovascular disease.The internationally recognized evaluation criteria should be adopted,and the stress should be put on the contribution of the research results and academic level.关键词：ischemic cerebrovascular diseases;cinical literature;resuscitation inducing technique;needling Baihui （DU20） through Qubin （GB7）;Jiao’s three-needle technique;temporal three-needle technique
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发布时间：2021-09-15 -
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