最新刊期
      卷 32 ， 期 12 ， 2009
      • WANG Zhong~1,JI Zheng-han~1,JIANG Miao~1,DING Xiao-rong~1,LV Ai-ping~1,SHEN Chun-ti~2
        Vol. 32, Issue 12, Pages: 797-799(2009)
        摘要：The report and publication outlines of TCM clinical single case were screened out through cording historical literature.Some suggestions on the publication and process norms of clinical single case were offered after multiple revision,and the written requirement and traceability were determined from the aspects of brief abstract,background,general information,chief complaint,disease history,diagnosis, treatment,discussion,expert estimate and reference.The TCM clinical cases with representative,actual effect and ductility were presented in order to improve the quality of case report and show the individual curative effect of Chinese medicine.  
        关键词：case report;publication;norms;construction   
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      • WU Hong-dong,WANG Qi
        Vol. 32, Issue 12, Pages: 800-802(2009)
        摘要：The most important cause of male immune infertility is the autoimmune response of the body.It is not all men,however,will suffer from infertility when they have autoimmune response.Male immune infertility is a pathological change induced by internal and external factors and the foundation is the disorders of homeostasis and adaptive regulating function（congenital constitution being abnormal）.The constitutional differentiation and treatment of male immune infertility should stress the amelioration of allergic constitution and regulation of body’s immunity.The level of allergen（sperm） and harmful immune response should be reduced to the lowest level.  
        关键词：male immune infertility;allergic Constitution;constitutional differentiation and treatment   
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      • Vol. 32, Issue 12, Pages: 802(2009)
        摘要：<正>中国高等学校自然科学学报研究会第6次会员代表大会暨第13次年会于2009年11月20～25日在广东省东莞市召开。年会期间公布了2009年全国高校科技期刊"三优"评比结果,《北京中医药大学学报》荣  
          
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      • Vol. 32, Issue 12, Pages: 803-805(2009)
        摘要：<正>张仲景在《金匮要略》中构建了杂病防治诊疗体系,其中"治未病"思想是很重要的一部分,在首篇即提出"上工治未病",说明"治未病"是评判医者高明与否的标准。继而又指出"若五脏元真通畅,人即安和",为"治未病"提供了指导原则。《金匮要略》一书比较全面科学地阐述了何谓治未病,怎样治未病,同时也论述了疾病发生、发展和传变规律。  
        关键词：金匮要略;五脏元真通畅;治未病   
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      • Vol. 32, Issue 12, Pages: 806-809(2009)
        摘要：<正>传统养生文化与《神农本草经》（以下简称《本经》）不无关系,从其独特功能药物的统计和构成分析,可以发现《本经》养生药物以辛、甘、苦味和性平之药为主,注重上品药物和非动物药、矿物药,尽管这些药物功能具有异见性和争议性,但对于养生药物的研究开发具有十分重要的意义。为此,本文从养生文化视角对《本经》养生方药构成进行了统计并加以分析。  
        关键词：神农本草经;养生方药;构成思考   
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      • Vol. 32, Issue 12, Pages: 809(2009)
        摘要：<正>《中医教育》创办于1982年,是教育部主管、北京中医药大学主办的中医药教育科学研究刊物。本刊物面向海内外公开发行,集导向性、学术性、研究性、应用性于一体,全方位服务于中医药教育事业。其读者对  
          
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      • YUE Li-feng,CHEN Jia-xu~#,WANG Da-wei,HUO Su-kun,YUE Guang-xin,LIANG Yuan,LI Jing-jing
        Vol. 32, Issue 12, Pages: 810-814(2009)
        摘要：Objective To investigate the mechanism of gene regulation of Xiaoyao Powder in the treatment of liver-stagnation and spleen-deficiency syndrome.Methods All SD rats（n=75） were randomly divided into 5 groups,including the normal group,model group,sham-operation group,CNQX group and Xiaoyao Powder group.The model was established by chronic restraint for 21 days and then CNQX group was given CNQX microinjection by cerebral stereotaxis instrument.The sham-operation group was set up for review the influence of operative injury on the model.The modeling method of Xiaoyao Powder group was as the same as possible with that of CNQX group for the comparison between these two groups.The expression changes of GluR1-mRNA and GluR2-mRNA were detected,which were two important subunits in CA1 and CA3 regions of hippocampus and AMPA receptor of amygdala,by one-step RT-PCR method.The trends of indexes in all regions were compared between CNQX group and Xiaoyao Powder group.Results The expressions of GluR1-mRNA and GluR2-mRNA had no statistical significance among the normal group,CNQX group and Xiaoyao Powder group in CA1 and CA3 regions of hippocampus（all P>0.05）.In BLA region of amygdala the expressions of GluR1-mRNA and GluR2- mRNA reached the lowest in CNQX group because the antagonism of CNQX to AMPA receptor,but had no statistical significance between the normal group and Xiaoyao Powder group（all P>0.05）.The trends of the expressions of GluR1-mRNA and GluR2-mRNA in hippocampus and amygdala were similar showed by RT-PCR in CNQX group and Xiaoyao Powder group after dismissing confounding factors like operative injury.Conclusion The regulating mechanism of Xiaoyao Powder to the expressions of subunits of hippocampus and amygdala AMPA receptor may be coincidence with that of CNQX in rat model of liver-stagnation and spleen-deficiency syndrome.It is deduced that Xiaoyao Powder cures liver-stagnation and spleen-deficiency syndrome through correcting the disorder of"excitation-inhibition"of hippocampus and amygdala and reconstructing the homeostasis.  
        关键词：Xiaoyao Powder;liver-stagnation and spleen-deficiency syndrome;gene;regulating mechanism;AMPA receptor;rats   
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      • Vol. 32, Issue 12, Pages: 814(2009)
        摘要：<正>本刊是由国家教育部主管、北京中医药大学主办的中医药学术期刊。主编为中国中医界学术权威王永炎院士。主要面向国内外中医药医学院校的师生,各级各类医院的临床医生等。本刊现已被中文生物医学  
          
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      • GONG Yan-bing~1,NI Qing~1,GAO Si-hua~
        Vol. 32, Issue 12, Pages: 815-818(2009)
        摘要：Objective To investigate the correlation between the relevant indexes of plasma glucose and TCM symptoms and syndrome types in the patients with different complications of type 2 diabetes. Methods On the base of clinical data from 2 501 cases of type 2 diabetes Bayesian network technique was applied to analyse the network relation among 82 variables including fasting plasma glucose,2-hour postprandial plasma glucose,glycated hemoglobin,syndrome,tongue and pulse in the patients with type 2 diabetes accompanied by encephalopathy,nephrosis and hypertension.Results In the patients with type 2 diabetes accompanied by encephalopathy when the indexes of fasting plasma glucose and 2-hour postprandial plasma glucose were abnormal the syndrome type was qi deficiency mainly,and when the index of glycated hemoglobin was abnormal the syndrome types were qi deficiency and yin deficiency commonly.In the patients with type 2 diabetes accompanied by nephrosis when the indexes of fasting plasma glucose were abnormal the syndrome type was yang deficiency mainly,and when the indexes of 2- hour postprandial plasma glucose and glycated hemoglobin were abnormal the syndrome types were mainly qi deficiency,or qi deficiency combined with excessive heat and yin deficiency.In the patients with type 2 diabetes accompanied by hypertension when the indexes of fasting plasma glucose,2-hour postprandial plasma glucose and glycated hemoglobin were abnormal the syndrome types were mainly yin deficiency or yin deficiency combined with excessive heat.The predictability of complications by common syndromes was observed.Conclusion Bayesian network technique is apposite to the objective research of TCM syndromes.This study is a reference to the early prediction of chronic complications of type 2 diabetes, and also explores initially the objective research of TCM syndromes.  
        关键词：type 2 diabetes;complications;TCM syndromes;indexes related to plasma glucose;Bayesian network   
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      • GUO Zhou~1,YANG Xue-zhi~1,Si Yin-chu~1,ZHU Qing-wen~1,NIU Xin~
        Vol. 32, Issue 12, Pages: 819-821(2009)
        摘要：Objective To observe which pathways（or components） of common color spaces are good for discriminating and segmenting tongue body and fur.Methods The typical tongue image（pink tongue with thin-white fur,greasy fur and yellow fur） and lower color temperature tongue image were taken as study objects,and special color component of every pixel of tongue imagines（value of a*,L*,H and R） in the color spaces of red,green and blue（RGB ）,L * a*b* criterion of International Commission on Illumination in 1976（CIELAB）,and hue,saturation and intensity（HSI） were selected as clustering objects.K-means clustering was applied to generate two clusters and complete the segmentation according to the characteristics of them.Results The component of a* value of CIELAB color space was the best in the segment effect and anti-interference capability,which was not influenced by illumination angle,bias of color temperature and types of tongue body and fur.The clustering results of L* value and R value were influenced by uneven illumination significantly.The clustering result of H value showed a state of incomplete segmentation. Conclusion The segmentation of tongue body and fur had a stable result taking a* value in CIELAB color space based K-means clustering as index and showed practical values in tongue diagnosis.  
        关键词：tongue diagnosis;color space;segmentation of tongue body and fur;K-means clustering   
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      • NIU Xu-yan,GU Li-gang~#,ZHANG Chun-jing,WANG Fu
        Vol. 32, Issue 12, Pages: 822-825(2009)
        摘要：Objective To observe the influences of Dureping Injection and Tanreqing Injection in different doses on the relative transcriptional activity of reporter gene NF-κB and expression of TNF-α-mRNA in human embryo renal epithelial cell（HEK-293T） infected by influenza virus-FM1,and to investigate the mechanism of anti-FM1 with Chinese herbal remedies（CHR） with the actions of clearing heat and removing toxin.Methods The influences of Dureping Injection,Tanreqing Injection and Ribavirin Injection on the proliferation of HEK-293T were examined by applying MTT test.After HEK- 293T infected by FM1,the relative activity of lueiferase of NF-κB in different groups interfered by different doses of Dureping Injection and Tanreqing Injection by using dual-lueiferase cis-reporting system with Ribavirin Injection as the control.The expression level of TNF-α-mRNA was detected by RT-PCR in different groups.Results The result of MTT test showed that Dureping Injection,Tanreqing Injection and Ribavirin Injection in different doses had no influences on the normal proliferation of HEK-293T （P>0.05）.The result of reporter gene detection showed that the transcriptional activity of NF-κB increased significantly（P<0.05） in the FM1 group compared with the control group.Dureping Injection （1 mg/L,10 mg/L and 100 mg/L）,Tanreqing Injection（1/300,1/200 and 1/100 dilution） and Ribavirin Injection（0.05 g/L） regulated respectively downward the transcriptional activity of NF-κB in varying degrees（P<0.01 ） compared with the FM1 group.The result of RT-PCR showed that the expression of TNF-α-mRNA increased significantly in the FM1 group（P<0.05） compared with the control group,while decreased significantly in injection group（P<0.01） compared with the FM1 group （P<0.01 ）.Conclusion One of the mechanisms of Dureping Injection and Tanreqing Injection for treating influenza may be that they can influence the expression of TNF-αand relieve the lung lesion and inflammatory reaction through down-regulating the transcriptional activity of NF-κB.  
        关键词：influenza virus-FM1;Chinese herbal remedies with the actions of clearing heat and removing toxin;transcription factor-NF-κB;tumor necrosis factor;dual-lueiferase cis-reporting system   
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      • LI Ning~1,TANG Qi-sheng~2,ZHAO Rui-zhen~2,GOU Sheng-le~1
        Vol. 32, Issue 12, Pages: 826-829(2009)
        摘要：Objective To investigate the interventional effect of Danzhixiaoyao Powder from the aspect of ethology in rats with chronic stress-induced anxiety.Methods The rat model of chronic stress-induced anxiety was established by using the stimulation of uncertainty empty bottle.The changes of exploratory, grooming and attack behaviors were observed when rats were stimulated by empty bottle.After the stress the ethology of rats were reviewed by applying international elevated plus-maze（EPM） test.The interventional effect of Danzhxiaoyao Powder was observed.Results The rats were irritable after the stress and had frequency grooming and attack behaviors.The result of EPM test showed that the rats were not willing to enter or stay in the open arm,but tended to explore the block arm and stay in there for a longer time.The motor activity of the rats decreased.After the intervene of Danzhixiaoyao Powder the grooming and attack behaviors of rats were reduced significantly,the total motor activity increased,and exploring times and stay time in the open arm were improved.Conclusion The model of chronic psychological stress by the stimulation of uncertainty empty bottle simulates well the anxiety in rats etiologically.Danzhxiaoyao Powder has a significant anti-anxiety effect.  
        关键词：anxiety model;ethology;chronic emotion tress;Danzhxiaoyao Powder;rats   
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      • ZHAO Ning-ning~1,LI Jun-xiang~
        Vol. 32, Issue 12, Pages: 830-833(2009)
        摘要：Objective To observe the influence of TCM therapy of regulating qi and activating blood circulation on the gene expression profile of gastric mucosa in rats with precancerosis of atrophic gastritis. Methods The rat model of precancerosis of atrophic gastritis was established by the synthetic method of metal spring insertion and feeding of NaCI solution and heat paste.The changes of differential gene expressions in the rats were detected by using gene chip technology after the intervention of the TCM therapy.The differential expression genes were screened and then identified by applying RT-PCR. Results There were totally 14 differential expression genes screened,and among them 8 were up-regulated genes and 6 were down-regulated genes.All of them consisted of the differential expression gene profile after the intervention of the TCM therapy in rat with precancerosis of atrophic gastritis,among which ptk2 was regulated significantly downward in the spontaneous recovery group and regulated significantly upward after the intervention of the TCM therapy.Conclusion The TCM therapy of regulating qi and activating blood circulation can regulate upward the gene expression of ptk2 in order to regulate the remodeling of actin cytoskeleton,and improve the repairing and healing of gastric mucosa.It is may be one of the mechanisms of the TCM therapy for treating precancerosis of atrophic gastritis.  
        关键词：therapy of regulating qi and activating blood circulation;atrophic gastritis;precancerosis;gene chip;gene identification;rats   
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      • XIA Zhong-yuan~1,PAN Lin~1,LI Hong~1,LI Yue-qing~
        Vol. 32, Issue 12, Pages: 834-838(2009)
        摘要：Objective To observe the effect of Shugantongluo Formula on cyclomastopathy in rats and the mechanism.Methods All unpregnancy female Wistar rats（n = 84） were randomly divided into the blank control group（group 1）,model group（group 2）,tamoxifen group（group 3）,Rupixiao group（group 4）, and high-dose,mid-dose and low-dose Shugantongluo Formula group（group 5,6 and 7,each n = 12）. The rat model of cyclomastopathy was established by injecting benzoate estradiol and progestogen intramuscularly for 30 days.The histomorphological changes of mammary glands,uterus and ovary,and the quantity and diameter of mammary lobule and alveolus were observed.The serum levels of estradiol（E2）, progesterone（P ）,prolactin（PRL ）,luteal hormone（LH ）,follicle-stimulating hormone（FSH ）, testosterone（T）,and estrogen receptor（ER） and progesterone receptor（PR） in mammary glands were detected.Results In group 5,6 and 7 the quantity of mammary lobule,and quantity and diameter of alveolus were reduced（P<0.01 ） and the serum E2 level was decreased with a significant difference compared with group 2（P<0.01）.In group 5 and 6 the level of P was increased with a significant difference compared with group 2（P<0.05）.In group 5 the level of PRL was decreased with a significant difference compared with group 2（P<0.05 ）.The levels of FSH,LH and T had no significant changes without difference compared with group 2（P>0.05）.In group 5 and 6 the expressions of ER and PR were regulated downward,which values was different significantly compared with those in group 2（P<0.05, P<0.01） and had no difference compared with those in group 3（P>0.05）.Shugantongluo Formula inhibited the paraplasm of uterus and ovary tissue.Conclusion Shugantongluo Formula has a therapeutic effect on cyclomastopathy in rats,and the mechanism may be related to that it can correct the disorder of endocrine hormones,and inhibit the higher expressions of ER and PR in mammary glands.  
        关键词：cyclomastopathy;Shugantongluo Formula;pharmacological effect;serum hormones;rats   
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        发布时间：2021-05-20
      • LI Li,ZHANG Cun,XIAO Yong-qing~#,LIN Na,LIU Chun-fang,LI Gui-liu,PANG Zhen,CHEN Dong-dong,TIAN Guo-fang
        Vol. 32, Issue 12, Pages: 839-841(2009)
        摘要：Objective To compare the changes of HPLC peaks of different kinds of Dahuang（Radix et Rhizoma Rhei） decoction pieces,and discuss the change laws of chemical constituents of these decoction pieces in the processing course.Method The procedure of HPLC fingerprint chromatogram was performed on the column of Zorbax Eclipse XDB-C18（4.6 mm×250 mm,5μm）,using methanol-glacial acetic acid（1.0%） as gradient elution at the temperature of 30℃,and the mobile phase was at flow rate of 1.0 mL/min.The detection wavelength was at 280 nm.The changes of peak areas of the same constituent in different decoction pieces were compared in 10 batches of 5 kinds of Dahuang decoction pieces.Result Among 24 identified peaks the content of gallic acid（1） was the highest,and the content of 5 kinds of free anthraquinone including aloe-emodin（20）,rhein（21 ）,emodin（22）, chrysophanol（23） and physcion（24） reached the highest in prepared Dahuang.The content of 4’- hydroxy-phenyl-2-butanone-4′-O-β-D-（6″-galloyl）-glucopyranoside（6）,emodin 8-O-glucoside（17） and aloe-emodin-3-CH2-O-β-D-glucosidase（18） were the highest in rude Dahuang and the content of other constituents were the highest in wine-treated Dahuang.Conclusion The main factors influencing the chemical constituents of Dahuang decoction pieces before and after processing include the kinds of excipients,temperature and heating time.The higher temperature or longer heating time will reduce the content of anthraquinone glycosides and increase the content of free anthraquinones in varying degrees.  
        关键词：Dahuang（Radix et Rhizoma Rhei）;decoction pieces;chemical constituents;change laws   
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      • ZHANG Cui-ying~1,CHANG Duan-ling~2,ZHOU Ying-qun~
        Vol. 32, Issue 12, Pages: 842-845(2009)
        摘要：Objective To set up an analysis method of fingerprint chromatogram of the water-soluble constituents of Wula’er Gancao（Glycyrrhiza uralensis Fisch） by HPLC,and lay a foundation for the quality control of medical material of Wula’er Gancao and Gancao Extractum.Methods The procedure of RP-HPLC was performed on a chromatographic column of Waters SunfireTMC18（4.6 mm×150 mm,5μm）,using methanol-phosphoric acid water solution（0.1%） as the gradient elution,and the mobile phase was at flow rate of 1.0 mL/min.The detection wavelength was at 260 nm and the analysis time was 95 minutes at the temperature of 25℃.HPLC fingerprint chromatograms of 12 batches of Wula’er Gancao samples from main production area were analyzed.Results Under the above chromatographic conditions, 18 chromatographic peaks consisted of the characteristic peak of fingerprint chromatogram of the water-soluble constituents of Wula’er Gancao through similarity analysis,among which 4 were identified. Conclusion The fingerprint chromatogram of water-soluble constituents of Wula’er Gancao set up by RP-HPLC is simple,stable and repeatable,which can be used to lay a foundation for the quality control of medical material of Wula’er Gancao and Gancao Extractum.  
        关键词：Wula’er Gancao（Glycyrrhiza uralensis Fisch）;water-soluble constituents;fingerprint chromatogram;HPLC   
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      • DONG Ling~1,ZHU Jing~2,WANG Yan-feng~2,LIU Jun~2
        Vol. 32, Issue 12, Pages: 846-848(2009)
        摘要：Objective To study the chemical constituents of Xueteng（Mucuna,dry rattan of Mucuna macrocarpa Wall.,Genus Mucuna,Family Papilionaceae）.Method There were 9 chemical compounds isolated from the ethanol（95%） extract and ethanol（60%） extract of dry rattan of Xueteng by applying the method of extraction,separation and purification.Result These 9 chemical compounds,after the identification of chemistry and spectrum,included friedelin（1）,epifriedelanol（2）,daucosterol（3）, vittadinoside（4）,β-sitosterol（5）,stigmasterol（6）,formononetin（7）,genistin（8） and daidzin （9）.Conclusion The above 9 chemical compounds were extracted from Xueteng for the first time.  
        关键词：Xueteng（Mucuna）;chemical constituents;structure identification   
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        发布时间：2021-05-20
      • FANG Qing-ying~
        Vol. 32, Issue 12, Pages: 849-851(2009)
        摘要：Objective To modify the differentiation method of TCL for Heshouwu（Radix Polygoni multiflori） and its decoction pieces in Pharmacopoeia of the People’s Republic of China（Edition 2005） and enlarge the examination items.Method The original TCL developing agent was changed and the TLC developing system of benzene-alcohol was replaced by the TLC developing system of chloroform-methanol.The examinations of moisture,ash and extract were revised and enlarged according to the method in the Appendix of Pharmacopoeia of the People’s Republic of China（Edition 2005）.Result The differentiation method of TCL for Heshouwu was revised to the TLC developing system of chloroform-methanol and a satisfactory result was obtained after two times of development.The limit for the moisture,total ash,acid-insoluble ash and extract made in this study was approved by the unit of validation and verification.Conclusion The TLC developing system of chloroform-methanol has the characteristic of lower toxicity and can be used in the differentiation method of TCL for Heshouwu.The relevant limit and examination of the moisture,total ash,acid-insoluble ash and extract are added for control the quality of Heshouwu totally.  
        关键词：Pharmacopoeia of the People’s Republic of China;Heshouwu（Radix Polygoni multiflori）;processed products;revision;TLC differentiation   
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      • GENG Li-dong,SHI Ren-bing~#,WANG Wei,SA Chu-la,Liang Ji-chun
        Vol. 32, Issue 12, Pages: 852-855(2009)
        摘要：Objective To establish a method for quantitative determination of 4 chemical constituentsgeniposide, genipin-1-β-D-gentiobioside,arctiin and baicalin in the effective fraction of Zhibangreduping Formula.Methods The procedure of HPLC was performed on the chromatographic column of Diamonsil C18（4.6 mm×150 mm,5μm）,and the mobile phase in the gradient elution was acetonitrile-phosphoric acid solution（0.2%）.The flow rate was 1.0 mL/min and the detection wavelength was 238 nm and 278 nm.Results The average recovery of geniposide was 99.02%（RSD = 1.99%,n = 6）,genipin-1-β-D-gentiobioside, 99.03%（RSD =2.83%,n=6）,arctiin,101.12%（RSD =2.86%,n=6）,and baicalin,100.05%（RSD =2.02%,n =6）.Conclusion The results of determination in 3 batches of samples show that the method is easy and accurate,which can be used in the quantitative determination of 4 chemical constituents in the effective fraction of Zhibangreduping Formula.  
        关键词：HPLC;arctiin;baicalin;genipin-1-β-D-gentiobioside;geniposide;quantitative determination   
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      • ZHANG Wen-xin,XUAN Lv,NI Jian~#
        Vol. 32, Issue 12, Pages: 856-858(2009)
        摘要：Objective To study the influence of temperature on the stability of salvianolic acid B in water solution.Methods The content changes of salvianolic acid B in control solution and water extract solution of Danshen（Radix Salviae Miltiorrhizae） were observed by applying the classic isothermal accelerated test.The results were compared in two experimental conditions.The order of reaction of salvianolic acid B along with temperature degradation was determined through mapping natural logarithm and time（lnC-t）,and t1/2 and t0.9 were predicted at different temperature.Results In two experimental conditions the content of salvianolic acid B accorded with the first-order kinetics equation with the changes of temperature.When temperature increased the content of salvianolic acid B decreased.The degradation speed of salvianolic acid B was higher in the control solution than that in the water extract solution of Danshen.Conclusion The stability of salvianolic acid B is very different at different temperature, which needs more attention in preparing course of the preparation containing salvianolic acid B.  
        关键词：Danshen（Radix Salviae Miltiorrhizae）;salvianolic acid B;temperature;stability   
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      • GE Jian-jun,SUN Li-hong~#,LI Xin-hua,SHE Yan-fen,YANG Ji-jun,LI Wen-li
        Vol. 32, Issue 12, Pages: 859-862(2009)
        摘要：Objective To observe the curative effect of indirect moxibustion in the treatment of primary dysmenorrhea of cold-damp coagulation type and study the mechanism.Methods All 209 patients with primary dysmenorrhea of cold-damp coagulation type were randomly divided into the treatment group（n= 105） treated with indirect moxibustion on the acupoints of Shenque（CV8） and Guanyuan（CV4）,and the control group（n = 104） treated with Yueyueshu Granules orally.After the treatment the curative effects were reviewed.The levels of menstrual serum prostaglandin F2α(PGF2α) and plasma arginine vasopressin（AVP） were detected before and after the treatment in parts of patients randomly and normal women.Results The curative effect of the treatment group was much better than that of the control group （P<0.01）.Before the treatment the levels of serum PGF2αand plasma AVP in two groups increased significantly than those in the normal women（all P<0.01）,while after the treatment those decreased significantly（P<0.01,P<0.05）.The comparison of PGF2α level between two groups showed a statistical difference（P<0.05）,but the level of serum PGF2α was higher in the control group than that in normal women（P<0.05）.Conclusion Indirect moxibustion had significant therapeutic effect on primary dysmenorrhea of cold-damp coagulation type,and the mechanism may be related to that it can reduce the levels of serum PGF2α and plasma AVP.  
        关键词：primary dysmenorrheal;cold-damp coagulation type;indirect moxibustion;serum prostaglandin F2α;plasma arginine vasopressin;clinical observation   
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      • Vol. 32, Issue 12, Pages: 862(2009)
        摘要：<正>《北京中医药大学学报》系中央级的高级中医药学术刊物,1959年创刊,由教育部主管、北京中医药大学主办。现分别属于中国自然科学核心期刊、中国中文核心期刊、全国中医药优秀期刊、全国优秀科技期刊、中  
          
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      • Vol. 32, Issue 12, Pages: 863-864(2009)
        摘要：<正>研究与运用乌梅丸,只有从方药组成中深入地分析与探索,才能发现乌梅丸不仅是主治蛔厥证的重要基础方,而且也是主治诸多内伤杂病的重要常用方,只有懂得乌梅丸主治并不局限于蛔厥证,才能更好的用活乌梅丸主治诸多疑难杂病,现将笔者临床运用乌梅丸的思路与方法介绍如下。  
        关键词：乌梅丸;经方;思路与方法;临床运用   
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      • Vol. 32, Issue 12, Pages: 873-874(2009)
        摘要：<正>北京中医药大学是教育部批准开展现代远程教育试点高校中的中医药高等院校。远程教育学院（原网络教育学院）是北京中医药大学开展远程教育的具体实施机构。根据教育部有关文件,北京中医药大学可"利用网络等现代化手段开展本、专科学历教育、学士学位教育","自行组织考试录取学生",对于"达到毕业要求的本、专科学生颁发成人高等教育毕业证书",并按规定办理毕业生的高等教育学历证书电子注册。  
          
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