最新刊期
卷 0 ， 期 0 ， 2020
- 摘要：<正>北京中医药大学是教育部批准开展现代远程教育试点高校中惟一的一所中医药高等院校。远程教育学院（原网络教育学院）是北京中医药大学开展远程教育的具体实施机构。根据教育部有关文件,北京中医药大学可"利用网络等现代化手段开展本、专科学历教育、学士学位教育","自行组织考试录取学生",对于"达到毕业要求的本、专科学生颁发成人高等教育毕业证书",并按规定办理毕业生的高等教育学历证书电子注册。
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发布时间：2021-05-20 - 摘要：TCM syndrome differentiation theory,syndrome acquisition process and latent variables, concealed structure thought were compared and analyzed briefly in this paper.The practical value of concealed structure method to syndrome study was discussed.The syndromes,as Latent Class Analysis （LCA）,search internal invisible"syndrome latent variables"through visible"symptom significant variables",and to set up syndrome latent variables,symptom significant variables and a concealed structure among syndrome latent variables.But the syndrome structure of TCM is acquired from the experience of human brain,and concealed structure model is established by computer based on relevant statistical principle through the analysis of symptom data collected from clinical epidemiological survey.The model is accorded with TCM syndrome differentiation theory with quantitative advantage,and can be thought as one of research methods of TCM syndrome objectification and quantification.关键词：TCM syndrome differentiation;syndromes;latent variables;concealed structure
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发布时间：2021-05-20 - 摘要：The time-sequence conception of five movements and six climatic factors in Plain Questions is a special TCM logos of temporal regularity,by which the chromatographic observation and set analysis were given from different temporal layers and angles of view based on the expression of spatial-temporal integration,harmonization of time circulation and movement in cycles,and the particular thought foundation of laminar analysis and convergent thinking goal motivity.The method of adjacent layer-by-layer superposition of five movements and six climatic factors was used to harmonize different laws.The migration and fluctuation of practical changes were corrected,steady substitution of time-sequence laws of five movements and six climatic factors was achieved,clinical practices were guided,and the goal of timesequence maintain was realized through the methods of alternate preponderance,stagnation-removing and deficiency and excess position-setting.关键词：Plain Questions;five movements and six climatic factors;time-sequence conception;separation and reunion;lingering and relapsing
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发布时间：2021-05-20 - 摘要：<正>作为仲景著作《伤寒杂病论》的重要组成部分,我国现存最早的较完整的治疗杂病的专著《金匮要略》一书,系北宋年间林亿等据翰林学士王洙在翰林院残存书籍中发现的《伤寒杂病论》的节略本《金匮玉函要略方》整理而成。在此之前,《金匮要略》的内容多散见于《脉经》《备急千金要方》《外台秘要》等医籍中,而关于此书校注发挥的研究专著,元末以前尚不多见。但此关键词：金匮要略;注家;沿革;学派
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发布时间：2021-05-20 - 摘要：<正>《黄帝内经》是现代人们谈养生的主要理论来源,其中的养生理论指导人们生活的各个方面,包括饮食养生、运动养生以及服饰养生等等。《黄帝内经》中有关服饰养生的论述包含据四季穿衣,据不同疾病状态穿衣以及淡泊的着装观念等几个方面。关键词：黄帝内经;服饰;养生
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发布时间：2021-05-20 - 摘要：<正>近日,《北京中医药大学学报》编辑部接到美国《国际药学文摘》（IPA）的通知,《北京中医药大学学报》自2007年开始正式成为IPA的来源期刊。国际药学文摘（International Pharmaceutical Abstracts,简称"IPA"）创办于1964年,由美国医院药师协会出版,1970年后实现了计算机化服务,其光盘数据库由美国银盘公司发行。IPA数据库主要用于检索和显示药学文献,范围包括药物临床和技术信息、药学研究、药学实践、药学教育、药学和药物的相关法律。数据库
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发布时间：2021-05-20 - 摘要：Objective To compare and study the characteristics of brain neuron apoptosis in rats with acute cerebral infarction of syndrome of qi deficiency and blood stasis.Methods The rat model of acute cerebral infarction of syndrome of qi deficiency and blood stasis was established by using continual exhaustive swimming combined with suture method,and then the brain paraffin sections was stained with Tdt-mediated dUTP nick end labeling（TUNEL）.The neuron apoptosis of cerebral caudate nucleus was observed and compared between the combined model group and normal group,single swimming control group or single suture control group.The quantity of apoptotic cells was calculated and cell lesion was analyzed with imaging analysis technique.Results There were a few apoptotic cells in the cerebral caudate nucleus in the normal group and single swimming control group,but a lot in the combined model group and single suture control group.In the combined model group there were much more apoptotic cells and cells were injured more seriously.Conclusion The brain neuron apoptosis,as microscopic characteristics,can be included into the review system of the model in rats with acute cerebral infarction of syndrome of qi deficiency and blood stasis.关键词：cell apoptosis;cerebral infarction;qi deficiency and blood stasis;imaging analysis;rats
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发布时间：2021-05-20 - 摘要：Objective To discuss the correlation between the common syndrome factors and symptoms of postmenopausal menopause syndrome.Method The clinical survey was carried out in 780 outpatients with postmenopausal menopause syndrome from 7 gradeⅢ-A hospitals in the whole country.On the basis of syndrome differentiation with expert experiences common syndrome factors of types according to the locations and natures of diseases were summed up.The correlation between common syndrome factors and symptoms were analyzed and studied by applying dichotomy Logistic regression analysis.Result The common syndrome factors of location type,including kidney,liver,spleen and heart,and syndrome factors of disease nature type,including qi stagnation,heat or fire,blood stasis,dampness,yin deficiency,qi deficiency,yang deficiency and deficiency were obtained.The correlation between the common syndrome factors and symptoms was found through the analysis on the regression model of common syndrome factors. For example,stringy pulse,anxious,distention,red tongue,irascibility,weakness pulse and lack of concentration were diagnostically significant in the judgment of liver,one of syndrome factors of location type,while fear of cold,cold limbs,frequent urination at night,slow pulse,loose stool,teeth-printed tongue and muscle tremor were diagnostically significant in the judgment of yang deficiency,one of syndrome factors of disease nature type.These tallied with the knowledge of TCM after the analysis on the regression model.There were some contentious symptoms to the judgment significance of syndrome factors, and mental symptoms were significant to the judgment of common syndrome factors.Conclusion The correlation between the common syndrome factors and symptoms of postmenopausal menopause syndrome was analyzed initially through clinical study,which provides a foundation for the diagnostic standard of syndrome factors.关键词：menopause syndrome;postmenopausal stage;syndrome factors;Logistic regression analysis
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发布时间：2021-05-20 - 摘要：<正>2008年11月3日教育部科学技术司发布《关于公布"第二届中国高校精品·优秀·特色科技期刊评比结果的通知"（教技司[2008]305号）》。经专家评审,共评出精品科技期刊76种,优秀科技期刊118种,特色科技期刊53种。《北京中医药大学学报》被评为中国高校精品科技期刊。
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发布时间：2021-05-20 - 摘要：Objective To study the renal protective effect of Tangshen Formula（TF）in rats with diabetic nephropathy.Methods All Wistar rats（n=50）were randomly divided into the blank group,model group,monopril group（0.83 mg/kg）,high-dose TF group（2.67 g/kg）and low-dose TF group（1.33 g/kg,each n=10）.The rat model of diabetic nephropathy was established by right-kidney nephrectomy and intraperitoneal injection of streptozotocin and then given the relevant drugs respectively for 20 weeks. The body weight,levels of blood glucose and ratio of urinary protein to creatinine were determined dynamically.When the trial was finished blood samples were taken from the abdominal aorta and plasma viscosity,the levels of total serum protein（TSP）,albumin,total cholesterol（TC）,triglyceride（TG）, blood urea nitrogen and creatinine were detected.The kidney tissue was taken for histopathological observation and lesion grade.Results Comparing with the model group,in the low-dose TF group the body weight increased significantly from 4th week（P<0.05）,and much significantly from 12th week （P<0.01）.In the high-dose TF group the ratio of urinary protein to creatinine decreased significantly （P<0.05）,the levels of plasma viscosity（P<0.05）,TC（P<0.05）and TG（P<0.01）decreased significantly,and glomerulosclerossi index（P<0.01）and tubular fibrosis index（P<0.01）reduced. The results of the high-dose TF group were better than those of the monopril group.Conclusion Tangshen Formula has a good renal protective effect in rats with diabetic nephropathy.The mechanism may be related to that it can relieve the disorders of hemorrheology and blood lipid metabolism.关键词：Tangshen Formula;diabetic nephropathy;renal function;histopathology;rats
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发布时间：2021-05-20 - 摘要：Objective To investigate the target organ lesion and its mechanism in rat model of qideficiency and blood-stasis syndrome from the aspect of glucose and lipid metabolism and oxidative stress reaction of heart and brain tissue.Method The rat model of qi-deficiency and blood-stasis syndrome was established by using exhaustive swimming.After 1,2 or 4 weeks the levels of blood glucose,blood lipid, serum lipoprotein,and the contents of malondialdehyde（MDA）and superoxide dismutase（SOD）of heart and brain tissue were detected respectively.Result In the model group the level of blood glucose increased after 1,2 or 4 weeks.The levels of plasma total cholesterol（TC）and triglyceride（TG） decreased,and high-density lipoprotein-C（HDL-C）and low-density lipoprotein-C（LDL-C）had no changes after 4 weeks.The content of heart MDA increased,and the contents of heart SOD,brain MDA and SOD had no significant changes in rats of model group.Conclusion The disorder of glucose and lipid metabolism is an important biological basis of qi-deficiency and blood-stasis syndrome.The target organ lesion may be related closely to oxidative stress reaction.关键词：exhaustive swimming;qi-deficiency and blood-stasis;energy metabolism;oxidative stress;rats
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发布时间：2021-05-20 - 摘要：Objective To review the quality of the security reports of randomized controlled trials about the treatment of diabetic nephropathy with TCM to improve the security reports of clinical trails of Chinese herbal remedies.Method The relevant documents about the randomized controlled trials were retrieved in the Chinese Periodicals Full-Text Database of CNKI and VIP Database from Jan.2006 to Sept.2008 taking"diabetic nephropathy"as the key word.The relevant data were collected respectively from the part of method,result and discussion in every paper.Result Among 286 papers 115（40.21%）reported the security indexes.There were 4 items reflecting security indexes summed up.The reports had the problems of disunity and non-standard.There were no causal inferences of epidemiology in the occurrence of adverse events and work-out of security conclusions.The methodology of the reports was not rigorous and normative.Conclusion The security reports of randomized controlled trials about the treatment of diabetic nephropathy with TCM do not pay more attention to the observation and record of relevant indexes.The occurrence of adverse events and work-out of security conclusions need causal inferences of epidemiology and statistical analysis based on epidemiological related principles.Some suggestions were given for future studies here.关键词：Chinese herbal remedies;diabetic nephropathy;security;methodology;quality review
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发布时间：2021-05-20 - 摘要：Objective To investigate the influence of common preparation methods of Radix Salviae Miltiorrhizae on the changes of its chemical compositions by applying the fingerprint chromatogram,and its dissolution characteristics for different times of extraction in the decoction of Radix Salviae Miltiorrhizae.Method The changes of chemical compositions and difference between extractable compositions and original compositions of CHR were compared before and after the preparation by applying HPLC fingerprint chromatogram and the control and analytic method of chemical standard samples.Result There were only protocatechualdehyde in the material and the slices of Radix Salviae Miltiorrhizae.There was no protocatechuic acid observed,but which was found out in the stirfrying slices with wine and then the relative content of protocatechualdehyde decreased at the same time.The liposoluble compositions of the slices was dissolved out uneasily in the decoction,while the most of watersoluble compositions were extracted out after extracting for two times.Conclusion It is difficult for the liposoluble compositions of slices of Radix Salviae Miltiorrhizae to dissolve into the decoction,which indicates that the effective material base（chemical compositions）of Radix Salviae Miltiorrhizae in the decoction should be its water-soluble compositions.关键词：Radix Salviae Miltiorrhizae;processing;decoction;chemical compositions;HPLC
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发布时间：2021-05-20 - 摘要：Objective To establish the method of quantitative determination in total phloroglucinol,and determine the contents of total phloroglucinol in commercial Rhizoma Dryopteris Crassirhizomae produced form different areas.Methods The visible spectrophotometry was used and dryocrassine ABBA was taken as the control sample and 0.5%saline solution of luxol fast blue BB as developing agent placed for 20 minutes for development at room temperature.The absorbance was detected with the wavelength of 476 nm,and the contents of total phloroglucinol in the samples were calculated with standard curve method. Results Dryocrassine ABBA showed a good linear relationship at range of 6.42-38.52μg（regression equation A=20.957C+0.013 3,r=0.999 6）with a high precision and RSD=1.44%.The sample solution was stable within 90 minutes after colour development and RSD=1.58%.The method had a high repeatability and RSD=2.11%with a high precision.The average recovery was 98.33%and RSD =1.08%（n=5）.Conclusion The method can be used for quantitative determination of total phloroglucinol in commercial Rhizoma Dryopteris Crassirhizomae.关键词：commercial Rhizoma Dryopteris Crassirhizomae;phloroglucinol;dryocrassine ABBA;quantitative determination;visible spectrophotometry
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发布时间：2021-05-20 - 摘要：Objective To set up HPLC method for quantitative determination of three compositions in total flavone fraction of Radix Scutellariae,including baicalin,wogonoside and baicalein.Method The HPLC method was performed on a column of WATERS-C18（250 mm×4.6 mm,5μm）,using methanol-water-phosphoric acid（47:53:0.2）as the mobile phase in gradient elution.The flow rate was 0.6 mL/min and detection wavelength was 280 nm.The temperature was at room temperature（24℃）.Result The average recovery of baicalin,wogonoside and baicalein was respectively 99.70%,100.06%and 100.85%.RSD was 2.47%,3.27%and 2.66%respectively.Conclusion The determination outcomes of three batches of samples showed that the method was simple and accurate,which can be used in the quantitative determination of three compositions in total flavone fraction of Radix Scutellariae.关键词：HPLC;Radix Scutellariae;total flavone fraction;baicalin;wogonoside;baicalein;quantitative determination
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发布时间：2021-05-20 - 摘要：Objective To investigate the risk stratification of essential hypertension（EH）and the correlation between TCM syndromes of EH and high-sensitivity C-reactive protein（Hs-CRP）.Methods The general conditions,disease history,TCM syndromes and multiple risk factors were collected from 86 patients with EH.The serum level of Hs-CRP was detected.The software of SPSS12.0 was used to analyzed different risk factors,risk stratification,and the relationship between relevant TCM syndromes and Hs-CRP.Results①After correcting the variables,such as sex,age,smoking history,blood lipid, blood glucose and family history of early cardiovascular disease through partial correlative analysis,the risk stratification was correlated to Hs-CRP（r=0.316,P<0.01）.②The level of Hs-CRP in the medial risk group,high risk group,very high risk group or acute coronary syndrome（ACS）group was higher significantly than that in the normal group（P<0.05）.③There were more cases of excess syndrome combined with deficiency syndrome in high risk group and very high risk group,accounting for 81%or more.④The level of Hs-CRP increased significantly in the cases of excess syndrome combined with deficiency syndrome than those of symptomless or of deficiency syndrome（P<0.05）.Conclusion The risk stratification of EH is correlated significantly to the level of Hs-CRP,which reflects the injury of EH to blood vessel and vulnerability to blood constituents,rather than the single hemodynamic significance of EH.The Hs-CRP monitoring,and prevention and treatment of EH should be begun from the medial risk patients of EH instead of high risk group.Some TCM syndromes of EH may be correlated to Hs-CRP level,and one of biological bases of many excess syndromes and syndrome combined excess with deficiency is abnormal increase of Hs-CRP level.关键词：essential hypertension;high-sensitivity C-reactive protein;risk stratification;TCM syndromes;relevant analysis
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发布时间：2021-05-20 - 摘要：Objective To discuss the personality characteristics of woman patients with malignant tumor of female genital organs of blood-stasis syndrome.Method The personality characteristics and psychosomatic health status of woman patients with female genital organ tumor（n=120）were determined with the Clinical Psychological Rating Scale（EPQ and SCL-90）and compared with patients with benign tumor and health control group.Result The proportion of blood-stasis syndrome in the malignant tumor group was higher than that in the benign tumor group.The neurological scores of emotion and factors of SCL-90 indexes（except paranoid factor）in the malignant tumor group were all higher than those in the normal group and benign tumor group with significant difference（P<0.05）.The result of Logistic regression analysis showed that the onset of malignant tumor of blood-stasis syndrome correlated significantly to anxiety factors and correlated negatively to character factors.Conclusion The blood-stasis syndrome is a common pathological syndrome of malignant tumor of female genital organs.The woman patients with malignant tumor of female genital organs of blood-stasis type have special personality characteristics and obvious psychosomatic problems,which indicates that the women with this constitutional trend are easy to suffer from malignant tumor.关键词：gynecological malignant tumor;blood-stasis syndrome;psychological factors;psychosomatic diseases;TCM constitutional theory
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发布时间：2021-05-20 - 摘要：<正>《北京中医药大学学报》已入编《中国学术期刊（光盘版）》。为此郑重声明如下:一、凡在《北京中医药大学学报》发表的文章,如作者事先未表示异议,则相应地被编入《中国学术期刊（光盘版）》。《中国学术期刊（光盘版）》免收作者版面费。
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发布时间：2021-05-20 - 摘要：Objective To observe the clinical effects of the therapy of replenishing qi,nourishing yin and activating blood circulation on urinary albumin excretion rate（UAER）and life quality in the patients with diabetic nephropathy（DN）.Method The patients（n=60）were randomly divided into the control group（n=30）and treatment group（n=30）.The control group was treated with integrated therapeutic method for DN and the treatment group was given the Chinese herbal remedies with the effects of replenishing qi,nourishing yin and activating blood circulation on the base of the integrated treatment of DN.Result In the treatment group UAER was decreased significantly（P<0.01）after 8 weeks,and the curative effect and life quality were improved significantly too.There was a significant difference between two groups（P<0.01）.Conclusion The therapy of replenishing qi,nourishing yin and activatingblood circulation can reduce UAER,improve life quality,and prevent and treat DN.关键词：diabetic nephropathy;therapy of replenishing qi,nourishing yin and activating blood circulation;life quality;urinary albumin excretion rate
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发布时间：2021-05-20 - 摘要：<正>为了实现科技期刊编辑、出版发行工作的电子化,推进科技信息交流的网络化进程,我刊现已入网"万方数据——数字化期刊群"。所以,向本刊投稿并录用的稿件文章,将一律由编辑部统一纳入"万方数据——数字化期刊群",提供网络信息服务。凡有不同意者,请另投它刊。本刊所付稿酬包含刊物内容上网服务报酬,不再另付。
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发布时间：2021-05-20 - 摘要：<正>原发生纤维肌痛综合征是以慢性弥漫性疼痛、乏力、睡眠障碍、腰背疼痛、情绪障碍为主要症状的疾病。临床发病率高,对患者的生活和工作影响较大。5年来我们在德国魁茨汀中医院应用中医药综合治疗该病共396例,取得了较好的疗效,现报道如下。关键词：纤维肌痛综合征;中医药;综合治疗
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发布时间：2021-05-20 - 摘要：Objective To compare the influence of kneading on acupoints of Yanglingquan（GB34）or Ashi on acute soft tissue injury in rabbits.Method The model of acute soft tissue injury was established by using soft tissue striking device in rabbits.All rabbits were then randomly divided into the normal group,model group,GB34 group and Ashi group.The finger kneading manipulation were applied to rub on the acupoints of Ashi and GB34 respectively.The changes of the contents ofβ-endorphin（β-EP）and 5-hydroxytryptamine（5-HT）in the peripheral blood and pathological changes of injured soft tissue were observed before and after the treatment.Results The finger kneading manipulation on the acupoints of Ashi or GB34 regulated the contents ofβ-EP and 5-HT in the peripheral blood and bring abirritation after the soft tissue was injured.The effect was better than that in the model group of self-healing.The finger kneading manipulation on the acupoints of Ashi or GB34 improved the repair of injured soft tissue and on GB34 was more effective.Conclusion The finger kneading manipulation on the acupoints of Ashi or GB34 has significant abirritation and ability of improving the repair of injured soft tissue,which indicates that GB34 can be kneaded in the early stage of acute soft tissue injury.关键词：finger kneading manipulation;Yanglingquan（GB34）;Ashi;soft tissue injury;tissue repair;rabbits
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发布时间：2021-05-20 - 摘要：<正>近日,《北京中医药大学学报》编辑部接到中国科学技术期刊编辑学会国际交流工作委员会、中国高等学校自然科学学报研究会对外联络委员会的通知:经过严格评估,《北京中医药大学学报》被美国《剑桥科学文摘》（CSA）、美国《乌利希期刊指南》（Ulrich PD）、《日本科学技术振兴机构中国文献数据库》（JST）列为其来源期刊,其中CSA、Ulrich PD首次收录时间为2007年。
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发布时间：2021-05-20 - 摘要：<正>北京中医药大学与北京针灸骨伤学院两校合并后,将《北京针灸骨伤学院学报》（1994年创刊）更名为《北京中医药大学学报（中医临床版）》（以下简称为本刊）,2003年3月正式出版发行。办刊几年来,本刊有了长足的发展,一切已经步入正常的运行轨道,但和其他同类优秀期刊相比,差距还很大,而且由于它诞生于一个出版行业飞速变革与发展的时关键词：问卷调查;期刊建设;期刊质量
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发布时间：2021-05-20 - 摘要：<正>《中医教育》创办于1982年,是教育部主管、北京中医药大学主办的国家级中医药教育科学研究刊物。本刊面向海内外公开发行,集导向性、学术性、研究性、应用性于一体,全方位服务于中医药教育事业。目前,《中医教育》属于中国核心期刊（遴选）数据库收录期刊,中文生物医学期刊文献数据库统计源期刊,万方数据资源系统数字期刊,中国期刊网、中国学术期刊（光盘版）全文收录期刊。关键词：中医教育;引证报告;指标分析
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发布时间：2021-05-20 - 摘要：<正>"中文生物医学期刊文献数据库——Chinese Medical Current Contents"（简称CMCC数据库）。《北京中医药大学学报》已被该数据库正式收录,凡有不同意将自己稿件纳入该数据库的作者,请另投它刊。本刊所付稿酬包含刊物内容被收录所付报酬,不再另付。
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发布时间：2021-05-20
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