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The mechanism of tonifying the kidney and essence in treating retinal degeneration based on the relation between kidney essence and stem cells

  • role： First author第一作者
  • Affiliation：

    Department of Eye Function Laboratory, Eye Hospital, China Academy of Chinese Medical Sciences, Beijing 100040, China

  • Introduction：李佳贤，男，在读博士生
LI Jiaxian1,  
  • role： Corresponding author通信作者
  • Affiliation：

    Department of Eye Function Laboratory, Eye Hospital, China Academy of Chinese Medical Sciences, Beijing 100040, China

  • Email：lianglina163@163.com
  • Introduction：LIANG Lina, Ph.D., Researcher, Chief Physician, Doctoral Supervisor. Department of Eye Function Laboratory, Eye Hospital, China Academy of Chinese Medical Sciences, No.33, Lugu Road, Shijingshan District, Beijing 100040. E-mail: lianglina163@163.com
LIANG Lina1*,  
  • Affiliation：

    Department of Eye Function Laboratory, Eye Hospital, China Academy of Chinese Medical Sciences, Beijing 100040, China

XU Kai1,  
  • Affiliation：

    Department of Eye Function Laboratory, Eye Hospital, China Academy of Chinese Medical Sciences, Beijing 100040, China

JIN Yu1

résumé

Stem cells, which have a high self-renewal capacity, high proliferation, and multi-directional differentiation potential, have shown broad prospects in the treatment of retinal degeneration. There are many similarities between the kidney essence and stem cells in the aspects of reproduction, growth and development, marrow and blood generation, nourishing zang-fu organs, and origin. In particular, there may be a relationship of theoretical identity between the congenital essence and stem cells. The traditional Chinese medicine pathogenesis of retinal degeneration is attributed to deficiency of the kidney essence and the loss of nourishment of the eyes. The treatment method is tonifying the kidney and essence. Mesenchymal stem cells belong to a class of stem cells. The method of tonifying the kidney and essence can significantly promote the migration, homing, differentiation, and paracrine of bone marrow mesenchymal stem cells. This article takes this as a starting point to explore the potential mechanism of the method of tonifying the kidney and essence in the treatment of retinal degeneration and provides new ideas and a theoretical basis for future research.

mots-clés

kidney essence;stem cells;method of tonifying the kidney and essence;retinal degeneration

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