Objective To study the correlation between chronic heart failure（CHF） and level creatine（Cr） based on heart energy metabolism.Methods The rat model of CHF after myocardial infarction was established.The heart-qi deficiency syndrome and cerebral function were reviewed through some indexes like general condition

physiology and hemodynamics of rat model.The level of Cr（myocardial energy substance） was detected by applying nuclear magnetic resonance spectrum（1HNMR）.The changes of Cr level were compared in all groups

and the correlation between heart-qi deficiency syndrome of CHF and Cr metabolism was studied.Results The rats of CHF model had significant symptoms of CHF and heart-qi deficiency syndrome.In the model group the rats had yellowish and dry hair

and were listless and inert.The respiratory rate（RR

P<0.01） and heart rate（HR

P<0.05

P<0.01） increased

exhausted swimming time（P<0.05

P<0.01） was shorter in the model group compared with those in the sham-operation group.The results of hemodynamics test showed that LVSP（P<0.05

P<0.01） and ±dP/dtmax（P<0.05

P<0.01） decreased significantly and LVEDP（P<0.05

P<0.01） increased significantly in the model group.The results of 1HNMR showed that Cr level decreased significantly in the model group（P<0.05

P<0.01）.The outcomes of correlation analysis showed that the systolic function of left ventricle was correlated to Cr level.±dP/dtmax was correlated significantly to Cr level on the 6th

9th and 12th week

which meant that Cr level was correlated to the systolic and diastolic function of left ventricle.Conclusion The results of this study indicated that heart-qi deficiency syndrome of CHF was correlated to Cr level.