Objective To observe the changes of enzyme which reflected the energy and lipid peroxidation of cardiac cells induced by Angiotensin II（AngII）

and different effects of some different Chinese herbs with the effects of replenishing qi and activating blood on these indexes.Method AngII was used in the cultured cardiac cells of SD mouse.The changes of contents of L-lactate dehydrogenase（LDH）

succinate dehydrogenase（SDH）

malondialdehyde（MDA） and activity of superoxide dismutase（SOD） in cell supernate were observed after 24

48

72 and 96 hours.The effects of above Chinese herbs were also observed.Result After 48 hours of AngII was used the contents of LDH

SDH and MDA decreased obviously（P<0.01） in cell supernate.The activity of SOD decreased obviously（P<0.01）

while in different groups with different Chinese herbs the contents of LDH

SDH and MDA increased obviously and the activity of SLD increased（P<0.05 or P<0.01）.Conclusion The function of cardiac cells was influenced by the changes of energy and lipid peroxidation induced by AngII.The Chinese herbs with the effects of replenishing qi and activating blood can protect the cardiac cells.