Objective To discuss the distribution law and internal characteristics of syndrome manifestations of chronic hepatitis B

and to provide a base for standardized study of syndrome manifestations.Method According to the principles of evidence-based medicine

the syndrome manifestations and syndrome factors in documents over the past ten years qualified to the selection standard were analyzed.Results The result showed that the most common syndrome manifestations successively were stagnancy in the liver leading to spleen-deficiency

insufficiency of liver-yin and kidney-yin

accumulation of damp-heat

deficiency of spleen-yang and kidney-yang

obstruction of blood stasis in collaterals

damp-heat in liver and gallbladder

qi stagnation and blood stasis

stagnation of liver-qi

liver depression and blood stasis

stasis of blood

deficiency of both spleen and kidney.The syndrome factors consisted of disease location and disease characters.The location included liver

gallbladder

spleen

kidney

stomach

Zhongjiao and collaterals.The characters included yin insufficiency

yang deficiency

qi deficiency

blood insufficiency

dampness

heat

qi stagnation

blood stasis

toxin

cold

water and phlegm.Conclusion This paper summed up the distribution law of common syndrome manifestations and syndrome factors and provided a base for standardized study on symptoms and signs of chronic hepatitis B.