Objective To observe the influence of Yuejubaohe Pills on gastroenteric movement and gastric secretion in experimental animals.Methods To establish the mouse model of the disorder of gastric（depletion） and small intestine advancement by using morphine and atropine

and the model of acceleration of gastric depletion and small intestine advancement by using neostigmine.The influence of Yuejubaohe Pills were observed on the gastroenteric movement in the normal model or the model with gastroenteric disorder

and on the gastric secretion

gastric acid secretion

peptic activity and gastric mucous weight in normal or water-immersion stress rats.Results ① Yuejubaohe Pills administrated orally had no（significant） influence on the gastric depletion and small intestine advancement in normal mice

but（improved） the gastroenteric movement in animal model of gastroenteric movement disorder

which（manifested） as relieving significantly the disorder of small intestine advancement induced by morphine and atropine

inhibiting gastric depletion

antagonizing significantly the acceleration of small intestine（advancement） induced by neostigmine

and had no significant influence on gastric depletion.② Yuejubaohe Pills administrated through duodenum decreased significantly gastric juice

total gastric acid secretion and mucous weight in normal rats and water-immersion stress rats.Conclusion Yuejubaohe Pills has the effects of regulating gastric secretion and gastroenteric movement.