基于“主客交”理论探讨慢性胃炎“炎癌转化”
Analysis on "inflammation-cancer transformation" of chronic gastritis based on the theory of "host-guest interaction"
- 北京中医药大学学报 2021年44卷第10期 页码：935-939
- 作者机构：
1.北京中医药大学东直门医院 北京 100700
2.北京中医药大学北京中医药研究院
3.北京中医药大学中医学院
- 作者简介：
施月，女，在读硕士生
#丁霞，女，博士，教授，博士生导师，主要研究方向：中西医结合防治消化系统疾病基础与临床研究，中医药抗肿瘤研究，E-mail: dingx@bucm.edu.cn
- 基金信息：国家自然科学基金重点项目(81630080);国家重点研发计划项目(2018YFC1704106);国家自然科学基金面上项目(82074243);国家自然科学基金青年项目(81903792);北京中医药大学东直门医院2020科技创新专项(DZMKJCX-2020-021)
DOI：10.3969/j.issn.1006-2157.2021.10.011
中图分类号： R256.3纸质出版日期：2021-10-30，
收稿日期：2021-03-16，
- 稿件说明：
移动端阅览
施月, 李萍, 李园, 等. 基于“主客交”理论探讨慢性胃炎“炎癌转化”[J]. 北京中医药大学学报, 2021,44(10):935-939.
Yue Shi, Ping Li, Yuan Li, et al. Analysis on "inflammation-cancer transformation" of chronic gastritis based on the theory of "host-guest interaction"[J]. Journal of Beijing University of Traditional Chinese Medicine, 2021,44(10):935-939.
施月, 李萍, 李园, 等. 基于“主客交”理论探讨慢性胃炎“炎癌转化”[J]. 北京中医药大学学报, 2021,44(10):935-939. DOI： 10.3969/j.issn.1006-2157.2021.10.011.
Yue Shi, Ping Li, Yuan Li, et al. Analysis on "inflammation-cancer transformation" of chronic gastritis based on the theory of "host-guest interaction"[J]. Journal of Beijing University of Traditional Chinese Medicine, 2021,44(10):935-939. DOI： 10.3969/j.issn.1006-2157.2021.10.011.
摘要
“主客交”理论出自吴又可所著《温疫论》，长期以来指导着临床痼疾的治疗。慢性胃炎“炎癌转化”是幽门螺杆菌感染、宿主、环境等多种因素共同参与的病理进展过程，其发生、发展与“主客交”正虚邪客，客邪胶固于血脉的病机特点极为相似。文章从“主客交”理论视角探讨慢性胃炎“炎癌转化”的病机演变，认为脾胃亏虚，致使湿热痰瘀毒胶固于胃络血脉，从而导致其恶性转化，并提出“扶正祛邪，解离主客”的基本治疗原则，强调重视主客两端，时刻顾护脾胃，扶正祛邪贯穿始终；厘清主客强弱，精准辨证，分阶段论治。
Abstract
The theory of "host-guest interaction" comes from
Wenyi Lun
(
Treatise on Pestilence
) written by Wu Youke and has been applied to the treatment of protracted diseases for a long time. "Inflammation-cancer transformation" of chronic gastritis is a pathological process of
Helicobacter pylori
infection
host
environment and other factors. And its occurrence and development are extremely similar to the pathogenesis characteristics of "host-guest interaction" the vital qi deficiency and pathogens invasion
pathogens adhere to the blood. The article discusses the pathogenesis of "Inflammation-cancer transformation" in chronic gastritis from the perspective of the theory of "host-guest interaction" . The deficiency of spleen and stomach causes the dampness
heat
phlegm
blood stasis and poison adhere to the blood of stomach collaterality
leading to the malignant transformation. This paper puts forward the basic treatment principle of "reinforcing the vital qi and eliminating the pathogenic factors
separating the host and guest"
and it emphasizes the importance of host-guest interaction. It suggests that treatment priority should be given to spleen and stomach
while reinforcing the vital qi and eliminating evil. Relative strengths and weaknesses of the host and guest should be identified to arrive at precise diagnosis and proper treatment by stages.
关键词
主客交慢性胃炎炎癌转化扶正祛邪
Keywords
host-guest interactionchronic gastritisinflammation-cancer transformationreinforcing the vital qi and eliminating evil
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